Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Lorenz Trümper"'
Autor:
Nicolaus Kröger, Gerald Wulf, Ute Hegenbart, Andreas Burchert, Matthias Stelljes, Nico Gagelmann, Arne Brecht, Martin Kaufmann, Lutz Müller, Arnold Ganser, Dominik Wolf, Wolfgang Bethge, Martin Bornhäuser, Michael Kiehl, Eva-Maria Wagner, Christoph Schmid, Hans Christian Reinhardt, Guido Kobbe, Hans Salwender, Thomas Heinicke, Martin Kropff, Marion Heinzelmann, Francis Ayuk, Lorenz Trümper, Andreas Neubauer, Andreas Völp, Evgeny Kluychnikov, Stefan Schönland, Christine Wolschke
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
The role of autologous-allogeneic tandem stem cell transplantation (alloTSCT) followed by maintenance as upfront treatment for multiple myeloma is controversial. Between 2008 and 2014 a total of 217 multiple myeloma patients with a median age of 51 y
Externí odkaz:
https://doaj.org/article/d16b172f3b0d40de80f3b187f9e3c4b7
Autor:
Hannes Treiber, Verena Nilius-Eliliwi, Nicole Seifert, Deepak Vangala, Meng Wang, Sabine Seidel, Thomas Mika, Dominik Marschner, Vanja Zeremski, Rebecca Wurm-Kuczera, Leandra Caillé, Claudia I. Chapuy, Lorenz Trümper, Thomas Fischer, Michael Altenbuchinger, Gerald G. Wulf, Gerald Illerhaus, Sascha Dietrich, Roland Schroers, Björn Chapuy
Publikováno v:
HemaSphere, Vol 7, Iss 8, p e926 (2023)
Secondary central nervous system lymphoma (SCNSL) is a rare and difficult to treat type of Non-Hodgkin lymphoma characterized by systemic and central nervous system (CNS) disease manifestations. In this study, 124 patients with SCNSL intensively trea
Externí odkaz:
https://doaj.org/article/e74a68f6168d4ee3a17dc8e62bf03165
Autor:
Theresa Bock, Moritz Bewarder, Onur Cetin, Natalie Fadle, Evi Regitz, Eva C. Schwarz, Jana Held, Sophie Roth, Stefan Lohse, Thorsten Pfuhl, Rabea Wagener, Sigrun Smola, Sören L. Becker, Rainer Maria Bohle, Lorenz Trümper, Reiner Siebert, Martin‐Leo Hansmann, Michael Pfreundschuh, Hans G. Drexler, Markus Hoth, Boris Kubuschok, Klaus Roemer, Klaus‐Dieter Preuss, Sylvia Hartmann, Lorenz Thurner
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 739-747 (2022)
Abstract Burkitt lymphoma (BL) represents the most aggressive B‐cell‐lymphoma. Beside the hallmark of IG‐MYC‐translocation, surface B‐cell receptor (BCR) is expressed, and mutations in the BCR pathway are frequent. Coincidental infections i
Externí odkaz:
https://doaj.org/article/dd8c74630d094db89e2da563ef835603
Autor:
Josefine Radke, Naveed Ishaque, Randi Koll, Zuguang Gu, Elisa Schumann, Lina Sieverling, Sebastian Uhrig, Daniel Hübschmann, Umut H. Toprak, Cristina López, Xavier Pastor Hostench, Simone Borgoni, Dilafruz Juraeva, Fabienne Pritsch, Nagarajan Paramasivam, Gnana Prakash Balasubramanian, Matthias Schlesner, Shashwat Sahay, Marc Weniger, Debora Pehl, Helena Radbruch, Anja Osterloh, Agnieszka Korfel, Martin Misch, Julia Onken, Katharina Faust, Peter Vajkoczy, Dag Moskopp, Yawen Wang, Andreas Jödicke, Lorenz Trümper, Ioannis Anagnostopoulos, Dido Lenze, Ralf Küppers, Michael Hummel, Clemens A. Schmitt, Otmar D. Wiestler, Stephan Wolf, Andreas Unterberg, Roland Eils, Christel Herold-Mende, Benedikt Brors, ICGC MMML-Seq Consortium, Reiner Siebert, Stefan Wiemann, Frank L. Heppner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Primary lymphomas of the central nervous system (PCNSL) are defined as diffuse large B-cell lymphomas (DLBCL) confined to the CNS. Here, the authors complete whole genome sequencing and RNA-seq to characterize 51 PCNSLs, and find common mutations in
Externí odkaz:
https://doaj.org/article/cd868cc84a9442afabebbc3638875fab
Autor:
Friederike Braulke, Florian Zettl, Marita Ziepert, Andreas Viardot, Christoph Kahl, Gabriele Prange-Krex, Agnieszka Korfel, Martin Dreyling, Alexander Bott, Ulrich Wedding, Dietmar Reichert, Maike de Wit, Frank Hartmann, Viola Poeschel, Norbert Schmitz, Mathias Witzens-Harig, Wolfram Klapper, Andreas Rosenwald, Gerald Wulf, Bettina Altmann, Lorenz Trümper
Publikováno v:
HemaSphere, Vol 6, Iss 12, p e808 (2022)
The incidence of aggressive B-cell lymphomas increases with age, but for elderly or frail patients not eligible for doxorubicin-containing treatment standard therapy remains to be defined. In this prospective, multicenter, phase-2 B-R-ENDA trial, we
Externí odkaz:
https://doaj.org/article/454022e1c0504a2caa116000c0379a95
Autor:
Henry Loeffler-Wirth, Markus Kreuz, Lydia Hopp, Arsen Arakelyan, Andrea Haake, Sergio B. Cogliatti, Alfred C. Feller, Martin-Leo Hansmann, Dido Lenze, Peter Möller, Hans Konrad Müller-Hermelink, Erik Fortenbacher, Edith Willscher, German Ott, Andreas Rosenwald, Christiane Pott, Carsten Schwaenen, Heiko Trautmann, Swen Wessendorf, Harald Stein, Monika Szczepanowski, Lorenz Trümper, Michael Hummel, Wolfram Klapper, Reiner Siebert, Markus Loeffler, Hans Binder, for the German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-20 (2019)
Abstract Background Germinal center-derived B cell lymphomas are tumors of the lymphoid tissues representing one of the most heterogeneous malignancies. Here we characterize the variety of transcriptomic phenotypes of this disease based on 873 biopsy
Externí odkaz:
https://doaj.org/article/eb092f16cead48828dfcb25f4bc14f5e
Autor:
Cristina López, Kortine Kleinheinz, Sietse M. Aukema, Marius Rohde, Stephan H. Bernhart, Daniel Hübschmann, Rabea Wagener, Umut H. Toprak, Francesco Raimondi, Markus Kreuz, Sebastian M. Waszak, Zhiqin Huang, Lina Sieverling, Nagarajan Paramasivam, Julian Seufert, Stephanie Sungalee, Robert B. Russell, Julia Bausinger, Helene Kretzmer, Ole Ammerpohl, Anke K. Bergmann, Hans Binder, Arndt Borkhardt, Benedikt Brors, Alexander Claviez, Gero Doose, Lars Feuerbach, Andrea Haake, Martin-Leo Hansmann, Jessica Hoell, Michael Hummel, Jan O. Korbel, Chris Lawerenz, Dido Lenze, Bernhard Radlwimmer, Julia Richter, Philip Rosenstiel, Andreas Rosenwald, Markus B. Schilhabel, Harald Stein, Stephan Stilgenbauer, Peter F. Stadler, Monika Szczepanowski, Marc A. Weniger, Marc Zapatka, Roland Eils, Peter Lichter, Markus Loeffler, Peter Möller, Lorenz Trümper, Wolfram Klapper, ICGC MMML-Seq Consortium, Steve Hoffmann, Ralf Küppers, Birgit Burkhardt, Matthias Schlesner, Reiner Siebert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Burkitt lymphoma (BL) is the most common pediatric B-cell lymphoma. Here, within the International Cancer Genome Consortium, the authors performed whole genome and transcriptome sequencing of 39 sporadic BL, describing the landscape of mutations, str
Externí odkaz:
https://doaj.org/article/0f2708368b2a4696b47220ee30732ce8
Autor:
Emmanuel Bachy, Alessandro Broccoli, Claire Dearden, Laurence de Leval, Philippe Gaulard, Raphael Koch, Franck Morschhauser, Lorenz Trümper, Pier Luigi Zinzani
Publikováno v:
HemaSphere, Vol 4, Iss 5, p e461 (2020)
Abstract. Peripheral T-cell lymphomas are a heterogeneous group of rare diseases with an aggressive behavior and dismal prognosis. Their classification is complex and still evolving, and several biomolecular markers now help refine the prognosis of s
Externí odkaz:
https://doaj.org/article/42b7fa58305f4a08be1313583cb496ee
Autor:
Lorenz Thurner, Sylvia Hartmann, Moritz Bewarder, Natalie Fadle, Evi Regitz, Claudia Schormann, Natalia Quiroga, Maria Kemele, Wolfram Klapper, Andreas Rosenwald, Lorenz Trümper, Rainer Maria Bohle, Anna Nimmesgern, Christina Körbel, Matthias W. Lascke, Michael D. Menger, Stefan Barth, Boris Kubuschok, Anja Mottok, Dominic Kaddu-Mulindwa, Martin-Leo Hansmann, Viola Pöschel, Gerhard Held, Niels Murawski, Stephan Stilgenbauer, Frank Neumann, Klaus-Dieter Preuss, Michael Pfreundschuh
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
It has been suggested that B-cell receptor (BCRs) stimulation by specific antigens plays a pathogenic role in diffuse large B-cell lymphoma (DLBCL). Here, it was the aim to screen for specific reactivities of DLBCL-BCRs in the spectrum of autoantigen
Externí odkaz:
https://doaj.org/article/931663a810f741b99241bc4117b18d0c
Autor:
Gerhard Schmalz, Lulzim Tulani, Rilana Busjan, Rainer Haak, Tanja Kottmann, Lorenz Trümper, Justin Hasenkamp, Dirk Ziebolz
Publikováno v:
Advances in Hematology, Vol 2020 (2020)
This retrospective pilot study aimed to detect whether remaining dental/periodontal treatment need and periodontal inflammation after dental clearance would be associated with the initial therapy outcome of adult patients with acute leukemia undergoi
Externí odkaz:
https://doaj.org/article/92dbb080f7ae43d58d2780821c3fc87d