Hypoxia-Inducible Factors as Key Players in the Pathogenesis of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis

Autor: Lorenz M. W. Holzner, Andrew J. Murray

Publikováno v: Frontiers in Medicine, Vol 8 (2021)

Non-alcoholic fatty liver disease (NAFLD) and its more severe form non-alcoholic steatohepatitis (NASH) are a major public health concern with high and increasing global prevalence, and a significant disease burden owing to its progression to more se

Externí odkaz: https://doaj.org/article/bb0f521c907c4a5db29fbd316a2ee347

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Hyperpolarized magnetic resonance shows that the anti‐ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post‐ischemic function in the diabetic heart

Autor: Lisa C. Heather, Dragana Savic, Vicky Ball, David Hauton, Lorenz M. W. Holzner, M. Kate Curtis, Kerstin N. Timm, Damian J. Tyler

Publikováno v: Nmr in Biomedicine

The diabetic heart has a decreased ability to metabolize glucose. The anti‐ischemic drug meldonium may provide a route to counteract this by reducing l‐carnitine levels, resulting in improved cardiac glucose utilization. Therefore, the aim of thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06174f6109423aae7352d8129c6a3da1
https://doi.org/10.1002/nbm.4471

Correction: Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration (PLoS One (2018) 13:4 (e0191172) DOI: 10.1371/journal.pone.0191172)

Autor: Lorenz M. W., Gao L., Ziegelbauer K., Norata G. D., Empana J. P., Schmidtmann I., Lin H. -J., McLachlan S., Bokemark L., Ronkainen K., Amato M., Schminke U., Srinivasan S. R., Lind L., Okazaki S., Stehouwer C. D. A., Willeit P., Polak J. F., Steinmetz H., Sander D., Poppert H., Desvarieux M., Arfan Ikram M., Johnsen S. H., Staub D., Sirtori C. R., Iglseder B., Beloqui O., Engstrom G., Friera A., Rozza F., Xie W., Parraga G., Grigore L., Plichart M., Blankenberg S., Su T. -C., Schmidt C., Tuomainen T. -P., Veglia F., Volzke H., Nijpels G., Willeit J., Sacco R. L., Franco O. H., Uthoff H., Hedblad B., Suarez C., Izzo R., Zhao D., Wannarong T., Catapano A., Ducimetiere P., Espinola-Klein C., Chien K. -L., Price J. F., Bergstrom G., Kauhanen J., Tremoli E., Dorr M., Berenson G., Kitagawa K., Dekker J. M., Kiechl S., Sitzer M., Bickel H., Rundek T., Hofman A., Mathiesen E. B., Castelnuovo S., Landecho M. F., Rosvall M., Gabriel R., De Luca N., Liu J., Baldassarre D., Kavousi M., De Groot E., Bots M. L., Yanez D. N., Thompson S. G.

An affiliation for Moise Desvarieux is missing. In addition to affiliation #22, Moise Desvarieux is affiliated with: METHODS Core, Centre de Recherche Epidémiologie et Statistique Paris Sorbonne Cité (CRESS), Institut National de la Santé et de la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::aa2c2f261a337f06e550ec1ab354d3c2
http://hdl.handle.net/11588/894097

Risk of symptomatic intracerebral hemorrhage in patients treated with intra-arterial thrombolysis

Autor: Singer, O. C., Berkefeld, J., Lorenz, M. W., Fiehler, J., Albers, G. W., Lansberg, M. G., Kastrup, A., Rovira, A., Liebeskind, D. S., Gass, A., Rosso, Charlotte, Derex, L., Kim, J. S., Neumann-Haefelin, T., Renseigné, Non

Publikováno v: Cerebrovascular Diseases
Cerebrovascular Diseases, 2009, 27 (4), pp.368-74. ⟨10.1159/000202427⟩
Cerebrovascular Diseases, Karger, 2009, 27 (4), pp.368-74. ⟨10.1159/000202427⟩

Background: In intra-arterial (IA) thrombolysis trials, higher rates of symptomatic intracerebral haemorrhage (sICH) were found than in trials with intravenous (IV) recombinant tissue plasminogen activator (tPA); this observation could have been due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ea3114abfc940a6ec987c62d17eeb9
https://inria.hal.science/hal-00796951