Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lorenz M. Hofmann"'
Autor:
Lorenz M. Hofmann, Thorwald Herbert
Publikováno v:
Journal of Computational Physics. 142:264-268
Autor:
Thorwald Herbert, Lorenz M. Hofmann
Publikováno v:
Physics of Fluids. 9:3727-3732
Laminar flow control methods employ some device to act on the flow. These devices, termed actuators, vary from blowing-suction holes, to heating strips, to wall-deflected membranes. We use computer simulations to optimize membrane actuators to genera
Publikováno v:
3rd Shear Flow Conference.
Autor:
Lorenz M. Hofmann, Richard M. Weier
Publikováno v:
Journal of Medicinal Chemistry. 18:817-821
A variety of esters of 17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid-gamma-lactone (7a) was synthetized in a sequence using the corresponding 3-oxo-4,6-diene (2) as starting material. The methyl (5), ethyl (7c), and isopropyl (7e)
Publikováno v:
Clinical Pharmacology & Therapeutics. 18:748-756
Potassium canrenoate was administered intravenously, twice at a 9-hr interval, to 3 apparently healthy male volunteers. No consistent changes in endogenous creatinine or PAH clearances were observed for 6 hr after the initial 200-mg dose of this aldo
Autor:
Lorenz M. Hofmann, Richard M. Weier
Publikováno v:
Journal of Medicinal Chemistry. 20:1304-1308
Several analogues of the previously reported steroidal spirolactone 1a were synthesized. These analogues bear C-6 substituents and include the 6beta-deuterio (1c), the 6beta-bromo (1d), the 6beta-methyl (1e), and the 6alpha-methyl (7) compounds. The
Autor:
Lorenz M. Hofmann, Theodore R. Sherrod
Publikováno v:
Experimental Biology and Medicine. 113:940-943
SummaryOuabain significantly increased the isometric twitch tension of the indirectly stimulated rat diaphragm. The diaphragm was analyzed for sodium, potassium and calcium content following exposure to ouabain, exposure to ouabain plus indirect stim
Autor:
William F. Johns, Lorenz M. Hofmann
Publikováno v:
Journal of Medicinal Chemistry. 16:568-570
Autor:
Lorenz M. Hofmann, Richard M. Weier
Publikováno v:
Journal of medicinal chemistry. 19(7)
The synthesis and antimineralocorticoid potencies of several steroidal spirolactones bearing novel nitrogenous substituents in the 7alpha position are reported. These substituents include the cyano, the isocyanato, and the alkoxycarbonylamino groupin
Autor:
Lorenz M. Hofmann, Richard M. Weier
Publikováno v:
Chemischer Informationsdienst. 6
A variety of esters of 17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid-gamma-lactone (7a) was synthetized in a sequence using the corresponding 3-oxo-4,6-diene (2) as starting material. The methyl (5), ethyl (7c), and isopropyl (7e)