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pro vyhledávání: '"Lorenz Hexemer"'
Autor:
Niklas Kolbe, Lorenz Hexemer, Lukas-Malte Bammert, Alexander Loewer, Mária Lukáčová-Medvid'ová, Stefan Legewie
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 6, p e1010266 (2022)
Cells sense their surrounding by employing intracellular signaling pathways that transmit hormonal signals from the cell membrane to the nucleus. TGF-β/SMAD signaling encodes various cell fates, controls tissue homeostasis and is deregulated in dise
Externí odkaz:
https://doaj.org/article/3bb50be3c3134aec800dc9093ba0e88b
State- and stimulus-specific dynamics of SMAD signaling determine fate decisions in individual cells
Autor:
Stefan Bohn, Lorenz Hexemer, Zixin Huang, Laura Strohmaier, Sonja Lenhardt, Stefan Legewie, Alexander Loewer
Publikováno v:
Proceedings of the National Academy of Sciences. 120
SMAD-mediated signaling regulates apoptosis, cell cycle arrest, and epithelial-to-mesenchymal transition to safeguard tissue homeostasis. However, it remains elusive how the relatively simple pathway can determine such a broad range of cell fate deci
Autor:
Niklas, Kolbe, Lorenz, Hexemer, Lukas-Malte, Bammert, Alexander, Loewer, Mária, Lukáčová-Medvid'ová, Stefan, Legewie
Publikováno v:
PLoS computational biology. 18(6)
Cells sense their surrounding by employing intracellular signaling pathways that transmit hormonal signals from the cell membrane to the nucleus. TGF-β/SMAD signaling encodes various cell fates, controls tissue homeostasis and is deregulated in dise