Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Lorenz, von Seidlein"'
Autor:
Sourav Nayak, Thomas J. Peto, Michal Kucharski, Rupam Tripura, James J. Callery, Duong Tien Quang Huy, Mathieu Gendrot, Dysoley Lek, Ho Dang Trung Nghia, Rob W. van der Pluijm, Nguyen Dong, Le Thanh Long, Ranitha Vongpromek, Huy Rekol, Nguyen Hoang Chau, Olivo Miotto, Mavuto Mukaka, Mehul Dhorda, Lorenz von Seidlein, Mallika Imwong, Xavier Roca, Nicholas P. J. Day, Nicholas J. White, Arjen M. Dondorp, Zbynek Bozdech
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The emergence of Plasmodium falciparum parasites resistant to artemisinins compromises the efficacy of Artemisinin Combination Therapies (ACTs), the global first-line malaria treatment. Artemisinin resistance is a complex genetic trait in wh
Externí odkaz:
https://doaj.org/article/29b3bb4812894fb0b0a2f1767eeb054b
Autor:
Kevin C. Kobylinski, Tri B. T. Satoto, Wisnu Nurcahyo, Yudi Ratna Nugraheni, Vincentius A. Testamenti, I Putu B. A. Winata, Yosua L. Pono, Diana Timoria, Piyanan Assawasuwannakit, Mary Chambers, J. Kevin Baird, Joel Tarning, Lorenz von Seidlein, Claus Bøgh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The mosquito-lethal effect of commercially available standard and long-lasting ivermectin formulations were evaluated in cattle and buffalo against wild-caught Anopheles on Sumba Island, Indonesia. Cattle have substantially higher blood-leve
Externí odkaz:
https://doaj.org/article/621e59cb959e417d8c4a4c33f9387017
Autor:
Borimas Hanboonkunupakarn, Mavuto Mukaka, Podjanee Jittamala, Kittiyod Poovorawan, Pongphaya Pongsuwan, Lisa Stockdale, Samuel Provstgaard-Morys, Kesinee Chotivanich, Joel Tarning, Richard M. Hoglund, Natenapa Chimjinda, Katie Ewer, Fernando Ramos-Lopez, Nicholas P. J. Day, Arjen M. Dondorp, Adrian V. Hill, Nicholas J. White, Lorenz von Seidlein, Sasithon Pukrittayakamee
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-8 (2024)
Abstract In preparation for mass vaccinations with R21/Matrix-M™ combined with mass administrations of dihydroartemisinin, piperaquine, and a single low dose primaquine we assessed the tolerability, safety, and potential interactions of this combin
Externí odkaz:
https://doaj.org/article/4be06bd127144f78b5cc122df3526075
Autor:
Lek Dysoley, James J. Callery, Voeurng Bunreth, Moul Vanna, Chan Davoeung, Yok Sovann, Sles You, Sam Ol, Rupam Tripura, Rusheng Chew, Arjun Chandna, Céline Christiansen-Jucht, Jayme Hughes, Nguon Sokomar, Top Sophornarann, Jeanne Rideout, Tat Veyvath, Oum Sarith, Thaung Puthy, Hay Sothearoth, Sen Sam An, Sazid Ibna Zaman, Lorenz von Seidlein, Lim Vanthy, Preap Sodavuth, Chrun Vannak, Arjen M. Dondorp, Yoel Lubell, Richard J. Maude, Thomas J. Peto, Bipin Adhikari
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract In Southeast Asia malaria elimination is targeted by 2030. Cambodia aims to achieve this by 2025, driven in large part by the urgent need to control the spread of artemisinin-resistant falciparum malaria infections. Rapid elimination depends
Externí odkaz:
https://doaj.org/article/41ade5fce8b5462da2c38af623dfedd8
Autor:
Kamala Thriemer, Robert James Commons, Megha Rajasekhar, Tamiru Shibiru Degaga, Krisin Chand, Nguyen Hoang Chau, Ashenafi Assefa, Mohammad Nader Naddim, Ayodhia Pitaloka Pasaribu, Awab Ghulam Rahim, Inge Sutanto, Tran Tinh Hien, Asrat Hailu, Mohammad Anwar Hasanzai, Lenny L. Ekawati, Adugna Woyessa, Tedla Teferi, Naomi Waithira, Walter R. J. Taylor, Benedikt Ley, Arjen Dondorp, J. Kevin Baird, Nicholas J. White, Nicholas P. Day, Ric N. Price, Julie A. Simpson, Lorenz von Seidlein
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Introduction Symptoms reported following the administration of investigational drugs play an important role in decisions for registration and treatment guidelines. However, symptoms are subjective, and interview methods to quantify them are
Externí odkaz:
https://doaj.org/article/0196663c2b3344ae812c8d3d8b46f20c
Autor:
Mipharny Betrian, Dafne Umans, Moul Vanna, Sam Ol, Bipin Adhikari, Chan Davoeung, James J Callery, Yok Sovann, Thomas J Peto, Richard J Maude, Rob W van der Pluijm, Voeurng Bunreth, Martin P Grobusch, Michèle van Vugt, Yoel Lubell, Lorenz von Seidlein, Arjen M Dondorp, Siv Sovannaroth, Dysoley Lek, Rupam Tripura
Publikováno v:
PLoS ONE, Vol 19, Iss 12, p e0315636 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0283405.].
Externí odkaz:
https://doaj.org/article/b9b84bac9cab435986d9f79afa653670
Autor:
Sarah A Cassidy-Seyoum, Keoratha Chheng, Phal Chanpheakdey, Agnes Meershoek, Michelle S Hsiang, Lorenz von Seidlein, Rupam Tripura, Bipin Adhikari, Benedikt Ley, Ric N Price, Dysoley Lek, Nora Engel, Kamala Thriemer
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 7, p e0003476 (2024)
Plasmodium vivax remains a challenge for malaria elimination since it forms dormant liver stages (hypnozoites) that can reactivate after initial infection. 8-aminoquinolone drugs kill hypnozoites but can cause severe hemolysis in individuals with Glu
Externí odkaz:
https://doaj.org/article/b899c555495b4fda90cbd9ac7dfc78e2
Autor:
Robert Harper, Benedikt Ley, Md Alamgir Kabir, Graham Matulis, Lorenz von Seidlein, Mohammad Shafiul Alam, Bipin Adhikari, Bernard A Okech, Alan L Williams, Ric N Price, Michael E von Fricken
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0297918 (2024)
Quantitative diagnosis of glucose-6-phosphate dehydrogenase (G6PD) deficiency is essential for the safe administration of 8-aminoquinoline based radical cure for the treatment of Plasmodium vivax infections. Here, we present the PreQuine Platform (IV
Externí odkaz:
https://doaj.org/article/5c7e6e12c84941cc846da31da411bc09
Autor:
Franca Conradis-Jansen, Rupam Tripura, Thomas J. Peto, James J. Callery, Bipin Adhikari, Mom Ean, Monnaphat Jongdeepaisal, Christopher Pell, Panarasri Khonputsa, Riccardo Murgia, Siv Sovannaroth, Olaf Müller, Phaik Yeong Cheah, Arjen M. Dondorp, Lorenz von Seidlein, Richard J. Maude
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-19 (2023)
Abstract Background Malaria transmission in Southeast Asia is increasingly confined to forests, where marginalized groups are exposed primarily through their work. Anti-malarial chemoprophylaxis may help to protect these people. This article examines
Externí odkaz:
https://doaj.org/article/fea6dfa83b8a4088913dfe5384fa6ded
Autor:
Li-Na Chen, Si-Jie Wang, Song-Mei Wang, Xiao-Li Fu, Wen-Jing Zheng, Zhi-Yong Hao, Hai-Song Zhou, Xin-Jiang Zhang, Yu-Liang Zhao, Chao Qiu, Lorenz von Seidlein, Tian-Yi Qiu, Xuan-Yi Wang
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background Norovirus is a leading cause of acute gastroenteritis among children. Previous studies based on symptomatic infections indicated that mutations, rather than recombination drove the evolution of the norovirus ORF2. These characteri
Externí odkaz:
https://doaj.org/article/31b6b84bef5c4de28ca1383fb7f548d9