Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lorenz, Rognoni"'
Autor:
Keith E. Steele, Tze Heng Tan, René Korn, Karma Dacosta, Charles Brown, Michael Kuziora, Johannes Zimmermann, Brian Laffin, Moritz Widmaier, Lorenz Rognoni, Ruben Cardenes, Katrin Schneider, Anmarie Boutrin, Philip Martin, Jiping Zha, Tobias Wiestler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background Immuno-oncology and cancer immunotherapies are areas of intense research. The numbers and locations of CD8+ tumor-infiltrating lymphocytes (TILs) are important measures of the immune response to cancer with prognostic, pharmacodyn
Externí odkaz:
https://doaj.org/article/7a113cf31f8c43b6a687bb8add920dde
Autor:
Peter Friedl, Dirk Lefeber, Stephan Kissler, Lorenz Rognoni, Bettina Weigelin, Marina Krause-Vortmeyer, Luisa Bracci, Mietske Wijers-Rouw, Veronika te te Boekhorst, Mariska te Lindert, Joost te Riet, Samuel Schmidt, Jack A.M. Fransen, Anthea J. Messent, Kay-Eberhard Gottschalk, Barbara Lelli, Martin J. Humphries
SummaryCell migration is a force-dependent adaptive process mediated by integrin-dependent adhesion as well as other yet poorly defined interactions to the extracellular matrix. Using enzymatic multi-targeted digestion of sugar moieties on the surfac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::184c55122f084abbd3a57ea925ae5ab7
https://doi.org/10.1101/2020.06.12.149096
https://doi.org/10.1101/2020.06.12.149096
Publikováno v:
Methods in enzymology. 635
Multiplex immunofluorescence (MIF) staining of tumor sections combined with computational pathology quantifies phenotypic variants of tumor and immune cells and assesses their spatial relationships. Here, we discuss a MIF panel composed of cytokerati
Multiplex immunofluorescence (MIF) staining of tumor sections combined with computational pathology quantifies phenotypic variants of tumor and immune cells and assesses their spatial relationships. Here, we discuss a MIF panel composed of cytokerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16a8f72bda2f5db4a6b317f9ca73c3d9
https://doi.org/10.1016/bs.mie.2019.07.039
https://doi.org/10.1016/bs.mie.2019.07.039
Autor:
Rieneke van de Ven, Sophie E. Willis, Marco Testori, Megha Saraiya, Michael Surace, Harald Hessel, Mari Heininen-Brown, Tanja D. de Gruijl, Sriram Sridhar, Felix Segerer, Emma Jones, Lorenz Rognoni, Anatoliy Shumilov, Jorge Blando, Andreas Spitzmüller, Julie Berthe, Helen K. Angell, Felicia S.L. Ng, Alma Andoni
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A46-A46
BackgroundTertiary Lymphoid Structures (TLS) are highly organized ectopic lymphoid structures found in inflamed or tumor tissues, acting as sites of lymphoid recruitment and immune activation. A high TLS density within the tumor is commonly associate
Autor:
Sonja Althammer, Tobias Wiestler, Marie-Caroline Dieu-Nosjean, Scott A. Hammond, Koustubh Ranade, Diane Damotte, Brandon Higgs, Helene Kaplon, Marlon Rebelatto, Moritz Widmaier, Thomas Herz, Andreas Spitzmüller, Marco Alifano, Tze Heng Tan, Keith E Steele, Lorenz Rognoni, Guenter Schmidt
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1 (2019)
Journal for Immunotherapy of Cancer, 2017, 7, ⟨10.1186/s40425-019-0589-x⟩
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1 (2019)
Journal for Immunotherapy of Cancer, 2017, 7, ⟨10.1186/s40425-019-0589-x⟩
Background Immune checkpoint therapies (ICTs) targeting the programmed cell death-1 (PD1)/programmed cell death ligand-1 (PD-L1) pathway have improved outcomes for patients with non-small cell lung cancer (NSCLC), particularly those with high PD-L1 e
Autor:
Johannes Zimmermann, Keith Steele, Lorenz Rognoni, Moritz Widmaier, Katrin Schneider, Tobias Wiestler, Anmarie Boutrin, Brian Laffin, Jiping Zha, Tze Heng Tan, Karma Dacosta, Philip Martin, Charles Brown, René Korn, Ruben Cardenes, Michael Kuziora
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-14 (2018)
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-14 (2018)
Background Immuno-oncology and cancer immunotherapies are areas of intense research. The numbers and locations of CD8+ tumor-infiltrating lymphocytes (TILs) are important measures of the immune response to cancer with prognostic, pharmacodynamic, and
Autor:
V. Pawar, Michael Surace, J. Rodriguez Canales, A. Spitzmüller, Lorenz Rognoni, D. Chain, T.-H. Tan
Publikováno v:
Journal of Thoracic Oncology. 14:S502
Autor:
Keith E Steele, J. Zimmermann, Nicolas Brieu, A. Spitzmüller, M. Groher, Guenter Schmidt, Marlon Rebelatto, Lorenz Rognoni, Michael Surace, Jaime Rodriguez-Canales, F. Segerer, H. Musa, A. Schäpe, A. Ackermann, A. Kapil, T.-H. Tan
Publikováno v:
Annals of Oncology. 30:v505
Background The tumor immune microenvironment (TIME) may hold critical information for developing and optimizing immuno-therapeutic approaches, identifying predictive signatures, and selecting the most adequate treatment option for a given patient. Ti
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(15)
Proline switches, controlled by cis–trans isomerization, have emerged as a particularly effective regulatory mechanism in a wide range of biological processes. In this study, we use single-molecule mechanical measurements to develop a full kinetic