Hyperthyroidism-driven bone loss depends on BMP receptor Bmpr1a expression in osteoblasts

Autor: Franziska Lademann, Eddy Rijntjes, Josef Köhrle, Elena Tsourdi, Lorenz C. Hofbauer, Martina Rauner

Publikováno v: Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)

Abstract Hyperthyroidism is a well-known trigger of high bone turnover that can lead to the development of secondary osteoporosis. Previously, we have shown that blocking bone morphogenetic protein (BMP) signaling systemically with BMPR1A-Fc can prev

Externí odkaz: https://doaj.org/article/8b89a9a3c6184875be917878699170d0

EuCAPT White Paper: Opportunities and Challenges for Theoretical Astroparticle Physics in the Next Decade

Autor: Batista, R. Alves, Amin, M. A., Barenboim, G., Bartolo, N., Baumann, D., Bauswein, A., Bellini, E., Benisty, D., Bertone, G., Blasi, P., Böhmer, C. G., Bošnjak, Ž., Bringmann, T., Burrage, C., Bustamante, M., Bustillo, J. Calderón, Byrnes, C. T., Calore, F., Catena, R., Cerdeño, D. G., Cerri, S. S., Chianese, M., Clough, K., Cole, A., Coloma, P., Coogan, A., Covi, L., Cutting, D., Davis, A. C., de Rham, C., di Matteo, A., Domènech, G., Drewes, M., Dietrich, T., Edwards, T. D. P., Esteban, I., Erdem, R., Evoli, C., Fasiello, M., Feeney, S. M., Ferreira, R. Z., Fialkov, A., Fornengo, N., Gabici, S., Galatyuk, T., Gaggero, D., Grasso, D., Guépin, C., Harz, J., Herrero-Valea, M., Hinderer, T., Hogg, N. B., Hooper, D. C., Iocco, F., Isern, J., Karchev, K., Kavanagh, B. J., Korsmeier, M., Kotera, K., Koyama, K., Krishnan, B., Lesgourgues, J., Said, J. Levi, Lombriser, L., Lorenz, C. S., Manconi, S., Mapelli, M., Marcowith, A., Markoff, S. B., Marsh, D. J. E., Martinelli, M., Martins, C. J. A. P., Matthews, J. H., Meli, A., Mena, O., Mifsud, J., Bertolami, M. M. Miller, Millington, P., Moesta, P., Nippel, K., Niro, V., O'Connor, E., Oikonomou, F., Paganini, C. F., Pagliaroli, G., Pani, P., Pfrommer, C., Pascoli, S., Pinol, L., Pizzuti, L., Porto, R. A., Pound, A., Quevedo, F., Raffelt, G. G., Raccanelli, A., Ramirez-Ruiz, E., Raveri, M., Renaux-Petel, S., Ricciardone, A., Khalifeh, A. Rida, Riotto, A., Roiban, R., Rubio, J., Sahlén, M., Sabti, N., Sagunski, L., Šarčević, N., Schmitz, K., Schwaller, P., Schwetz, T., Sedrakian, A., Sellentin, E., Serenelli, A., Serpico, P. D., Sfakianakis, E. I., Shalgar, S., Silvestri, A., Tamborra, I., Tanidis, K., Teresi, D., Tokareva, A. A., Tolos, L., Trojanowski, S., Trotta, R., Uhlemann, C., Urban, F. R., Vernizzi, F., van Vliet, A., Villante, F. L., Vincent, A., Vink, J., Vitagliano, E., Weniger, C., Wickenbrock, A., Winter, W., Zell, S., Zeng, M.

Astroparticle physics is undergoing a profound transformation, due to a series of extraordinary new results, such as the discovery of high-energy cosmic neutrinos with IceCube, the direct detection of gravitational waves with LIGO and Virgo, and many

Externí odkaz: http://arxiv.org/abs/2110.10074

Overcoming statin resistance in prostate cancer cells by targeting the 3-hydroxy-3-methylglutaryl-CoA-reductase

Autor: Göbel, Andy, Pählig, Sophie, Motz, Anja, Breining, Dorit, Traikov, Sofia, Hofbauer, Lorenz C., Rachner, Tilman D.

Publikováno v: In Biochemical and Biophysical Research Communications 28 May 2024 710

Utility and Limitations of TALLYHO/JngJ as a Model for Type 2 Diabetes–Induced Bone Disease

Autor: Lejla Emini, Juliane Salbach‐Hirsch, Johannes Krug, Katharina Jähn‐Rickert, Björn Busse, Martina Rauner, Lorenz C. Hofbauer

Publikováno v: JBMR Plus, Vol 7, Iss 12, Pp n/a-n/a (2023)

ABSTRACT Type 2 diabetes mellitus (T2DM) increases risk of fractures due to bone microstructural and material deficits, though the mechanisms remain unclear. Preclinical models mimicking diabetic bone disease are required to further understand its pa

Externí odkaz: https://doaj.org/article/617544c3b8574c5c893e33fbc5078247

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.