Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Lorene M. Lanier"'
Autor:
Katherine R. Tonn Eisinger, Paul G. Mermelstein, Mark J. Thomas, Daniel Tam, Erin B. Larson, Samuel P. Swanson, Lorene M. Lanier, Andrew D. Chapp, Natalie M. Lopresti
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Caveolin-1 (CAV1) is a structural protein critical for spatial organization of neuronal signaling molecules. Whether CAV1 is required for long-lasting neuronal plasticity remains unknown. OBJECTIVE AND METHODS: We sought to examine the eff
Autor:
Thomas W Bastian, William C von Hohenberg, Olivia R Kaus, Lorene M Lanier, Michael K Georgieff
Publikováno v:
J Nutr
BACKGROUND: Fetal-neonatal iron deficiency causes learning/memory deficits that persist after iron repletion. Simplified hippocampal neuron dendrite structure is a key mechanism underlying these long-term impairments. Early life choline supplementati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30ac932dc2d886287722f4b2df68da5
https://europepmc.org/articles/PMC8891184/
https://europepmc.org/articles/PMC8891184/
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Medium spiny neurons (MSNs) are the major striatal neuron and receive synaptic input from both glutamatergic and dopaminergic afferents. These synapses are made on MSN dendritic spines, which undergo density and morphology changes in association with
Externí odkaz:
https://doaj.org/article/13d0ac104c774a6f833ac73094b72e13
Publikováno v:
BioTechniques, Vol 23, Iss 4, Pp 728-735 (1997)
Treatment with 2 mM CuSO4 was used to induce a Drosophila melanogaster metallothionein (Mtn) promoter that had been cloned into a recombinant baculovirus. Careful study revealed that the Mtn promoter functioned as an inducible, if somewhat “leaky
Externí odkaz:
https://doaj.org/article/118b5ea32b86423783d76889e56e317f
Autor:
Adele L. DeNicola, Matthew V. Chafee, Russell E. Carter, Kelsey Schultz, Rachael K. Blackman, Theoden I. Netoff, Jennifer L. Zick, David W. Bergstrand, Timothy J. Ebner, David A. Crowe, Lorene M. Lanier
Publikováno v:
Curr Biol
Summary Schizophrenia results from hundreds of known causes, including genetic, environmental, and developmental insults that cooperatively increase risk of developing the disease. In spite of the diversity of causal factors, schizophrenia presents w
Autor:
Laura A Díaz-Martínez, Juan F Giménez-Abián, Yoshiaki Azuma, Vincent Guacci, Gonzalo Giménez-Martín, Lorene M Lanier, Duncan J Clarke
Publikováno v:
PLoS ONE, Vol 1, p e53 (2006)
BACKGROUND:The precision of the metaphase-anaphase transition ensures stable genetic inheritance. The spindle checkpoint blocks anaphase onset until the last chromosome biorients at metaphase plate, then the bonds between sister chromatids are remove
Externí odkaz:
https://doaj.org/article/2bb829e6407144e9aa551e5bb6d27c83
Autor:
Kari A. Duck, Thomas W. Bastian, James R. Connor, Michael J. Chen, Michael K. Georgieff, Martha Sola-Visner, Zhi-Jian Liu, Lorene M. Lanier, George C. Michalopoulos
Publikováno v:
Journal of Thrombosis and Haemostasis. 15:565-574
Essentials Potential neurodevelopmental side effects of thrombopoietin mimetics need to be considered. The effects of eltrombopag (ELT) on neuronal iron status and dendrite development were assessed. ELT crosses the blood-brain barrier and causes iro
Autor:
Thomas W. Bastian, Daniel J. Mickelson, Lorene M. Lanier, William C. von Hohenberg, Michael K. Georgieff
Publikováno v:
Developmental Neuroscience. 38:264-276
Iron deficiency (ID), with and without anemia, affects an estimated 2 billion people worldwide. ID is particularly deleterious during early-life brain development, leading to long-term neurological impairments including deficits in hippocampus-mediat
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(5)
During development, neurons require highly integrated metabolic machinery to meet the large energy demands of growth, differentiation, and synaptic activity within their complex cellular architecture. Dendrites/axons require anterograde trafficking o
Autor:
Marianne K. O. Grant, Rose Pitstick, Linda Kotilinek, George A. Carlson, Dezhi Liao, Rachel D. Penrod, Lorene M. Lanier, Karen H. Ashe, Jianjun Su, Brian R. Hoover, Li-Lian Yuan, Miranda N. Reed
Publikováno v:
Neuron. 68(6):1067-1081
SummaryThe microtubule-associated protein tau accumulates in Alzheimer's and other fatal dementias, which manifest when forebrain neurons die. Recent advances in understanding these disorders indicate that brain dysfunction precedes neurodegeneration