Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lorena T. Fernández-Martínez"'
Autor:
Jana K. Schniete, Pablo Cruz-Morales, Nelly Selem-Mojica, Lorena T. Fernández-Martínez, Iain S. Hunter, Francisco Barona-Gómez, Paul A. Hoskisson
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT The expansion of the genetic repertoire of an organism by gene duplication or horizontal gene transfer (HGT) can aid adaptation. Streptomyces bacteria are prolific producers of bioactive specialized metabolites that have adaptive functions i
Externí odkaz:
https://doaj.org/article/fa63f88793cd4fa6812bf72ef3840462
Autor:
Morgan Anne, Feeney, Jake Terry, Newitt, Emily, Addington, Lis, Algora-Gallardo, Craig, Allan, Lucas, Balis, Anna S, Birke, Laia, Castaño-Espriu, Louise K, Charkoudian, Rebecca, Devine, Damien, Gayrard, Jacob, Hamilton, Oliver, Hennrich, Paul A, Hoskisson, Molly, Keith-Baker, Joshua G, Klein, Worarat, Kruasuwan, David R, Mark, Yvonne, Mast, Rebecca E, McHugh, Thomas C, McLean, Elmira, Mohit, John T, Munnoch, Jordan, Murray, Katie, Noble, Hiroshi, Otani, Jonathan, Parra, Camila F, Pereira, Louisa, Perry, Linamaria, Pintor-Escobar, Leighton, Pritchard, Samuel M M, Prudence, Alicia H, Russell, Jana K, Schniete, Ryan F, Seipke, Nelly, Sélem-Mojica, Agustina, Undabarrena, Kristiina, Vind, Gilles P, van Wezel, Barrie, Wilkinson, Sarah F, Worsley, Katherine R, Duncan, Lorena T, Fernández-Martínez, Matthew I, Hutchings
Publikováno v:
Microbial genomics. 8(7)
Actinobacteria is an ancient phylum of Gram-positive bacteria with a characteristic high GC content to their DNA. The ActinoBase Wiki is focused on the filamentous actinobacteria, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d868894d099c1cf135e38e8b12cb6b52
https://pubmed.ncbi.nlm.nih.gov/35775972
https://pubmed.ncbi.nlm.nih.gov/35775972
Publikováno v:
Current Opinion in Microbiology. 51:16-21
Producing specialised metabolites such as antibiotics, immunosuppressives, anti-cancer agents and anti-helminthics draws on primary metabolism to provide the building blocks for biosynthesis. The growth phase-dependent nature of production means that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee247458d8ce737fe33176b1c498fad
https://doi.org/10.1016/j.mib.2019.03.006
https://doi.org/10.1016/j.mib.2019.03.006
Publikováno v:
Access Microbiology
Although soil is one of the largest microbial diversity reservoirs, the processes that define its microbial community dynamics are not fully understood. Improving our understanding of the levels of antibiotic resistance in soils with different land u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800d35dccc882c8ce96ea70acfa33bf0
https://pubmed.ncbi.nlm.nih.gov/33997612
https://pubmed.ncbi.nlm.nih.gov/33997612
Publikováno v:
Environmental Microbiology Reports. 10:231-238
The increase in availability of actinobacterial whole genome sequences has revealed huge numbers of specialised metabolite biosynthetic gene clusters, encoding a range of bioactive molecules such as antibiotics, antifungals, immunosuppressives and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17a4f25a77d7b26eed7d5ee63144d637
https://doi.org/10.1111/1758-2229.12629
https://doi.org/10.1111/1758-2229.12629
Publikováno v:
Access Microbiology. 1
Understanding the role of virulence loci within pathogenic organisms can be vital in exploring the evolution of disease. Streptomyces species are generally non-pathogenic soil saprophytes, yet within their genome we can find macrophage infectivity po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9512ef210b8b4466751c2e78fa2966a
https://doi.org/10.1099/acmi.ac2019.po0204
https://doi.org/10.1099/acmi.ac2019.po0204
Publikováno v:
Molecular Microbiology. 97:502-514
Summary Microbisporicin is a potent type I lantibiotic produced by the rare actinomycete Microbispora corallina that is in preclinical trials for the treatment of infections caused by methicillin-resistant isolates of Staphylococcus aureus (MRSA). An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9163f993cc8082798cfcaeff3d2d5497
https://doi.org/10.1111/mmi.13046
https://doi.org/10.1111/mmi.13046
Autor:
Chiara Borsetto, Juan Pablo Gomez-Escribano, Maureen J. Bibb, Mahmoud M. Al-Bassam, Lorena T. Fernández-Martínez, Govind Chandra, Mervyn J. Bibb
Publikováno v:
Antimicrobial Agents and Chemotherapy
Comparative genome analysis revealed seven uncharacterized genes, sven0909 to sven0915 , adjacent to the previously identified chloramphenicol biosynthetic gene cluster ( sven0916–sven0928 ) of Streptomyces venezuelae strain ATCC 10712 that was abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9a3e529480805f9c6ec5a53dfdf0c2
https://doi.org/10.1128/aac.04272-14
https://doi.org/10.1128/aac.04272-14
Publikováno v:
Environmental microbiology reports. 10(3)
The increase in availability of actinobacterial whole genome sequences has revealed huge numbers of specialised metabolite biosynthetic gene clusters, encoding a range of bioactive molecules such as antibiotics, antifungals, immunosuppressives and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fefae1b1737f6cab76c467d00258fa44
https://pubmed.ncbi.nlm.nih.gov/29457705
https://pubmed.ncbi.nlm.nih.gov/29457705
Expanding gene families helps generate the metabolic robustness required for antibiotic biosynthesis
Autor:
Iain S. Hunter, Francisco Barona-Gómez, Nelly Selem-Mojica, Pablo Cruz-Morales, Lorena T. Fernández-Martínez, Paul A. Hoskisson, Jana K. Schniete
Introductory paragraphExpanding the genetic repertoire of an organism by gene duplication or horizontal gene transfer (HGT) can aid adaptation. Streptomyces species are prolific producers of bioactive specialised metabolites with adaptive functions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefe43b8ae7d4c72691575c63953b064
