Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lorena Secades"'
Autor:
Clara Meana, José M. Rubín, Javier Bordallo, Lorena Secades, Carmen Bordallo, Begoña Cantabrana, Manuel Sánchez
Publikováno v:
Journal of Cardiovascular Pharmacology. 54:310-318
Androgens produce acute vasodilation of systemic, pulmonary, and coronary arteries in several mammal preparations and increase cardiomyocyte contractility. A decrease of the spontaneous beating of sinoatrial cells has also been described. The aim of
Autor:
María José García de Boto, Javier Bordallo, Agustín Hidalgo, Lorena Secades, Lucía Velasco, Carmen Bordallo, Begoña Cantabrana, José M. Rubín, Manuel Sánchez
Publikováno v:
Journal of Cardiovascular Pharmacology. 52:161-166
Functional and biochemical studies were performed in isolated left atria of male Wistar rats to study whether endogenous polyamines may mediate androgen-elicited positive inotropism and their relationship with a rise in cAMP during the cardiotonic ef
Autor:
Ashvin K. Dewan, Owen B. McManus, Martin Köhler, Ge Dai, William A. Schmalhofer, Gregory J. Kaczorowski, Maria L. Garcia, Manuel Sanchez, Markus Hanner, Lorena Secades, Hans Guenther Knaus
Publikováno v:
Biochemistry. 44:10135-10144
The role of ion channels in cell physiology is regulated by processes occurring after protein biosynthesis, which are critical for both channel function and targeting of channels to appropriate cell compartments. Here we apply biochemical and electro
Autor:
Javier Bordallo, Manuel Sánchez, Agustín Hidalgo, Rosario Cortina, Lorena Secades, Lucía Velasco
Publikováno v:
Pharmacology. 70:118-122
Pharmacological concentrations of androgens are known to elicit a rapid positive inotropism in isolated left atrium of male rats. Upon short-term exposure to androgens, an increase in intracellular cAMP levels has been observed, though delayed with r
Publikováno v:
European journal of pharmacology. 604(1-3)
Androgens elicit an acute cardiotonic effect in cardiac preparations of rats. This effect is produced via an extracellular interaction that may be coupled to pertussis-sensitive G-proteins and is associated with an increase in cAMP, polyamine synthes
Autor:
Lorena Secades, Carmen Bordallo, Clara Meana, Javier Bordallo, Begoña Cantabrana, Lucía Velasco, Manuel Sánchez, Miriam Méndez
Publikováno v:
European journal of pharmacology. 598(1-3)
Endogenous polyamines mediate acute metabolic effects and cardiac hypertrophy associated to beta-adrenoceptor stimulation. The aim of this study is to characterize the role of polyamines on beta-adrenoceptor system mediated responses. To this end, th