Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lorena Salgueiro"'
Autor:
Alicia Alonso de la Vega, Nuri Alpay Temiz, Rafail Tasakis, Kalman Somogyi, Lorena Salgueiro, Eleni Zimmer, Maria Ramos, Alberto Diaz-Jimenez, Sara Chocarro, Mirian Fernández-Vaquero, Bojana Stefanovska, Eli Reuveni, Uri Ben-David, Albrecht Stenzinger, Tanja Poth, Mathias Heikenwälder, Nina Papavasiliou, Reuben S. Harris, Rocio Sotillo
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background RNA editing has been described as promoting genetic heterogeneity, leading to the development of multiple disorders, including cancer. The cytosine deaminase APOBEC3B is implicated in tumor evolution through DNA mutation, but whet
Externí odkaz:
https://doaj.org/article/4370126016334153b5ad7b9bf80e0892
Autor:
Guillermo de Cárcer, Sharavan Vishaan Venkateswaran, Lorena Salgueiro, Aicha El Bakkali, Kalman Somogyi, Konstantina Rowald, Pablo Montañés, Manuel Sanclemente, Beatriz Escobar, Alba de Martino, Nicholas McGranahan, Marcos Malumbres, Rocío Sotillo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
PLK1 is a mitotic regulator overexpressed in cancer; however, whether this overexpression causally contributes to tumor development is unclear. Here the authors produce an inducible mouse model to overexpress PLK1 and show that actually this can act
Externí odkaz:
https://doaj.org/article/624e442f805148c5bac60f63e764f010
Autor:
Lorena Salgueiro, Christopher Buccitelli, Konstantina Rowald, Kalman Somogyi, Sridhar Kandala, Jan O Korbel, Rocio Sotillo
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 3, Pp n/a-n/a (2020)
Abstract Chromosome instability (CIN) has been associated with therapeutic resistance in many cancers. However, whether tumours become genomically unstable as an evolutionary mechanism to overcome the bottleneck exerted by therapy is not clear. Using
Externí odkaz:
https://doaj.org/article/225029ac68f7435d9344bd21f7538671
Autor:
Lorena Salgueiro, Susann Kummer, Vera Sonntag-Buck, Anne Weiß, Marc A. Schneider, Hans-Georg Kräusslich, Rocio Sotillo
Publikováno v:
J Virol
Respiratory viruses cause mild to severe diseases in humans every year, constituting a major public health problem. Characterizing the pathogenesis in physiologically relevant models is crucial for developing efficient vaccines and therapeutics. Here
Autor:
Kalman Somogyi, Konstantina Rowald, Christopher Buccitelli, Jan O. Korbel, Lorena Salgueiro, Rocio Sotillo, Sridhar Kandala
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 3, Pp n/a-n/a (2020)
EMBO Molecular Medicine, Vol 12, Iss 3, Pp n/a-n/a (2020)
Chromosome instability (CIN) has been associated with therapeutic resistance in many cancers. However, whether tumours become genomically unstable as an evolutionary mechanism to overcome the bottleneck exerted by therapy is not clear. Using a CIN mo
Autor:
Nicholas McGranahan, Guillermo de Cárcer, Konstantina Rowald, Beatriz Escobar, Rocio Sotillo, Alba de Martino, Pablo Montanes, Marcos Malumbres, Sharavan Vishaan Venkateswaran, Aicha El Bakkali, Kalman Somogyi, Manuel Sanclemente, Lorena Salgueiro
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Polo-like kinase 1 (Plk1) is overexpressed in a wide spectrum of human tumors, being frequently considered as an oncogene and an attractive cancer target. However, its contribution to tumor development is unclear. Using a new inducible knock-in mouse
Autor:
Nicholas McGranahan, Sharavan Vishaan Venkateswaran, Aicha El Bakkali, Beatriz Escobar, Manuel Sanclemente, Guillermo de Cárcer, Lorena Salgueiro, Marcos Malumbres, Pablo Montanes, Kalman Somogyi, Rocio Sotillo, Alba de Martino, Konstantina Rowald
Polo-like kinase 1 (Plk1) is a protein kinase currently considered as an attractive cancer target due to its critical role in the cell division cycle. Plk1 is overexpressed in a wide spectrum of human tumors, being frequently considered as an oncogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c782844326913d59441c2f65c80a226e