Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lorena S. Navigatore-Fonzo"'
Autor:
Carina Ledezma, Andrea Castro, Lorena S. Navigatore-Fonzo, Ana Cecilia Anzulovich, Cinthia Coria-Lucero, Silvia Marcela Delgado
Publikováno v:
Brain Research Bulletin. 170:106-114
Alzheimer's disease (AD) is a devastating disease characterized by loss of synapses and neurons in the elderly. Accumulation of the β-amyloid peptide (Aβ) in the brain is thought to be central to the pathogenesis of AD. ApoE plays a key role in nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c82ef3bcecd82e5e787a952af25254a
https://doi.org/10.1016/j.brainresbull.2021.01.014
https://doi.org/10.1016/j.brainresbull.2021.01.014
Autor:
María Belén Delsouc, Cinthia Coria-Lucero, Cristina Devia, Marilina Casais, Cecilia Della Vedova, Dario C. Ramirez, Lorena S. Navigatore-Fonzo, Carina Ledezma, Silvia Marcela Delgado, Ana Cecilia Anzulovich
Publikováno v:
Neuroscience. 458
Accumulation of amyloid peptides in the brain plays a key role in the pathogenesis of Alzheimer's disease (AD). Aggregated beta-amyloid (Aβ) peptide increases intracellular reactive oxygen species associated to a deficient antioxidant defense system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a59889560224166f0727f2706886f4
https://pubmed.ncbi.nlm.nih.gov/32827572
https://pubmed.ncbi.nlm.nih.gov/32827572
Autor:
Rebeca S. Golini, Leporatti Jorge, Maria Cecilia Della Vedova, Mauro Alfaro, Paula Mazaferro, Belén Delsouc, Lorena S. Navigatore Fonzo, Marilina Casais, Ana Cecilia Anzulovich, Dario C. Ramirez
Publikováno v:
Brain Research. 1767:147449
Alzheimer disease (AD) is the most frequent form of dementia in the elderly. It is characterized by the deterioration of memory and learning. The histopathological hallmarks of AD include the presence of extracellular deposits of amyloid beta peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd643498512ab87c5c9b8804f5b14ba3
https://doi.org/10.1016/j.brainres.2021.147449
https://doi.org/10.1016/j.brainres.2021.147449
Autor:
Ana Cecilia Anzulovich, Andrea Castro, Lorena S. Navigatore-Fonzo, Marilina Casais, Verónica Pignataro, Marisa Hilda Garraza
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The accumulation of amyloid-β (Aβ) peptides in the brain of Alzheimer disease patients is associated to cognitive deficit, increased oxidative stress, and alterations in the circadian rhythms. Brain-derived neurotrophic factor (BDNF) and Neurograni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1805a64296df5a3ee22bd7bfaa6a1008
https://doi.org/10.1016/j.brainres.2017.01.033
https://doi.org/10.1016/j.brainres.2017.01.033
One of the main pathological features in the Alzheimer disease (AD) is the presence of senile plaques, primarily composed of Aβ peptide aggregates, in cortex and hippocampus. AD late onset, which constitutes 90% of cases, could be mainly attributabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b2554f285837c2907495b1ad33d480
https://www.sciencedirect.com/science/article/abs/pii/S0928468019300082
https://www.sciencedirect.com/science/article/abs/pii/S0928468019300082
Autor:
Lorena S. Navigatore-Fonzo, Ana Cecilia Anzulovich, Silvia Marcela Delgado, Cinthia Coria-Lucero, Ivana Tamara Ponce, Rebeca S. Golini, Nicolas Deyurka
Publikováno v:
Brain Research. 1653:51-58
Aging brain undergoes several changes leading to a decline in cognitive functions. Memory and learning-related genes such as Creb, Bdnf and its receptor TrkB, are expressed in different brain regions including prefrontal cortex. Those genes' proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e32c8dc1cfa42c7b99dde7a8c75556a
https://doi.org/10.1016/j.brainres.2016.10.019
https://doi.org/10.1016/j.brainres.2016.10.019
Autor:
Emilse Silvina Sanchez, Nidia N. Gomez, Lorena S. Navigatore Fonzo, Silvina M. Alvarez, María Sofía Giménez
Publikováno v:
Psychiatry and Neuroscience Update-Vol. II ISBN: 9783319531250
Clinical studies have revealed that depression is accompanied by impaired brain function and cognitive performances or neurodegenerative processes. Moreover, accumulation of oxidative damage has been implicated in aging and various neurological disor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffbdbd86173bb8b4e0629aadda7bbb26
https://doi.org/10.1007/978-3-319-53126-7_35
https://doi.org/10.1007/978-3-319-53126-7_35
Publikováno v:
Nutrition Research. 34:326-335
The main external time giver is the day-night cycle; however, signals from feeding and the activity/rest cycles can entrain peripheral clocks, such as the hippocampus, in the absence of light. Knowing that vitamin A and its derivatives, the retinoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c5cf9796205decd6973609535be2ec
https://doi.org/10.1016/j.nutres.2014.02.002
https://doi.org/10.1016/j.nutres.2014.02.002
Autor:
Ana Cecilia Anzulovich, Silvia Marcela Delgado, Ivana Tamara Ponce, Maria G. Plateo-Pignatari, Lorena S. Navigatore-Fonzo, María Sofía Giménez, Rebeca Laura Golini
Publikováno v:
The Journal of Nutritional Biochemistry. 24:859-867
An endogenous time-keeping mechanism controls circadian biological rhythms in mammals. Previously, we showed that vitamin A deficiency modifies clock BMAL1 and PER1 as well as BDNF and neurogranin daily rhythmicity in the rat hippocampus when animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd93f5cc5d2929ff2fcaa6c0c5eea4fc
https://doi.org/10.1016/j.jnutbio.2012.05.006
https://doi.org/10.1016/j.jnutbio.2012.05.006
Autor:
Silvia Marcela Delgado, María Sofía Giménez, Myrtha R. Bonomi, Ana C. Anzulovich, Ivana Tamara Ponce, Lorena S. Navigatore Fonzo, Rebeca S. Golini, Irma Rezza
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Animals can adapt their behavior to predictable temporal fluctuations in the environment through both, memory-and-learning processes and an endogenous time-keeping mechanism. Hippocampus plays a key role in memory and learning and is especially susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a911f15cb958ed292a0cb57761dfcb
https://doi.org/10.1002/hipo.20571
https://doi.org/10.1002/hipo.20571