Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Lorena Pochini"'
Autor:
Lorena Pochini
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Polyamines interact with different molecular targets to regulate a vast range of cellular processes. A network of enzymes and transport systems is crucial for the maintenance of polyamine homeostasis. Indeed, polyamines after synthesis must be distri
Externí odkaz:
https://doaj.org/article/055164fb56f6498aaca33254e8b1aaee
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8743 (2024)
OCTN1 and OCTN2 are membrane transport proteins encoded by the SLC22A4 and SLC22A5 genes, respectively. Even though several transcripts have been predicted by bioinformatics for both genes, only one functional protein isoform has been described for e
Externí odkaz:
https://doaj.org/article/cc006afc6aee4619a910bceb7d659af2
Autor:
Omar Ben Mariem, Luca Palazzolo, Beatrice Torre, Yao Wei, Davide Bianchi, Uliano Guerrini, Tommaso Laurenzi, Simona Saporiti, Emma De Fabiani, Lorena Pochini, Cesare Indiveri, Ivano Eberini
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304512 (2024)
The Organic Cation Transporter Novel 1 (OCTN1), also known as SLC22A4, is widely expressed in various human tissues, and involved in numerous physiological and pathological processes remains. It facilitates the transport of organic cations, zwitterio
Externí odkaz:
https://doaj.org/article/142668bdd25f42b9ae9ac75c8fd01b1e
Autor:
Lorena Pochini, Michele Galluccio, Lara Console, Mariafrancesca Scalise, Ivano Eberini, Cesare Indiveri
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 392 (2024)
Inflammation is a physiological condition characterized by a complex interplay between different cells handled by metabolites and specific inflammatory-related molecules. In some pathological situations, inflammation persists underlying and worsening
Externí odkaz:
https://doaj.org/article/e599cf5177134ca3acc91aecbac10af1
Autor:
Michele Galluccio, Tiziano Mazza, Mariafrancesca Scalise, Martina Tripicchio, Martina Scarpelli, Maria Tolomeo, Lorena Pochini, Cesare Indiveri
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 536 (2023)
The human SLC7A10 transporter, also known as ASC-1, catalyzes the transport of some neutral amino acids. It is expressed in astrocytes, neurons, and adipose tissues, playing roles in learning, memory processes, and lipid metabolism, thus being involv
Externí odkaz:
https://doaj.org/article/ae5ff6eeaff844d6896f8442518ef610
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 15, Iss 2, Pp 207-219 (2020)
Among the different targets of administered drugs, there are membrane transporters that play also a role in drug delivery and disposition. Moreover, drug-transporter interactions are responsible for off-target effects of drugs underlying their toxici
Externí odkaz:
https://doaj.org/article/f883f6cb800c48c7ae49977680f80502
Publikováno v:
ACS Omega, Vol 5, Iss 5, Pp 2069-2080 (2020)
Externí odkaz:
https://doaj.org/article/b6d06f7dea814a11a04687bbf6c6f317
Autor:
Lorena Pochini, Michele Galluccio
Publikováno v:
Life, Vol 12, Iss 8, p 1206 (2022)
For more than 20 years, yeast has been a widely used system for the expression of human membrane transporters. Among them, more than 400 are members of the largest transporter family, the SLC superfamily. SLCs play critical roles in maintaining cellu
Externí odkaz:
https://doaj.org/article/b21aa3ee008e4686b5687036cfcdc3a5
Autor:
Michele Galluccio, Lara Console, Lorena Pochini, Mariafrancesca Scalise, Nicola Giangregorio, Cesare Indiveri
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3823 (2022)
Ten percent of human genes encode for membrane transport systems, which are key components in maintaining cell homeostasis. They are involved in the transport of nutrients, catabolites, vitamins, and ions, allowing the absorption and distribution of
Externí odkaz:
https://doaj.org/article/6ba1845077364a13ac4b43a319874a8b
Autor:
Lara Console, Mariafrancesca Scalise, Tiziano Mazza, Lorena Pochini, Michele Galluccio, Nicola Giangregorio, Annamaria Tonazzi, Cesare Indiveri
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Metabolic flexibility is a peculiar hallmark of cancer cells. A growing number of observations reveal that tumors can utilize a wide range of substrates to sustain cell survival and proliferation. The diversity of carbon sources is indicative of meta
Externí odkaz:
https://doaj.org/article/265e179e1e9040f5b413ed85e7271e67