Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lorena Pérez-Carrillo"'
Autor:
Lorena Pérez-Carrillo, Isaac Giménez-Escamilla, Irene González-Torrent, Marta Delgado-Arija, Ignacio Sánchez-Lázaro, María García-Manzanares, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract Long non-coding RNAs (lncRNAs) are closely implicated in biological processes and diseases with high inflammatory components. These molecules exhibit significant temporal and tissue specificity. However, the expression and function of lncRNA
Externí odkaz:
https://doaj.org/article/cd9317c670b14bbaafd5fbfba7ebb52b
Autor:
Marta Delgado-Arija, Patricia Genovés, Lorena Pérez-Carrillo, Irene González-Torrent, Isaac Giménez-Escamilla, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Cardiac fibroblast activation protein (FAP) has an emerging role in heart failure (HF). A paradoxical reduction in its levels in pathological conditions associated with acute processes has been observed. We aimed to identify FAP c
Externí odkaz:
https://doaj.org/article/7f007be5ed3a4a35954fc3151842bf82
Autor:
Isaac Giménez-Escamilla, Lorena Pérez-Carrillo, Irene González-Torrent, Marta Delgado-Arija, Carlota Benedicto, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9590 (2024)
Heart failure (HF) is associated with global changes in gene expression. Alternative mRNA splicing (AS) is a key regulatory mechanism underlying these changes. However, the whole status of molecules involved in the splicing process in human HF is unk
Externí odkaz:
https://doaj.org/article/3dbf8751b6c849f6ad19e566e9e6a09c
Autor:
Isaac Giménez-Escamilla, Carlota Benedicto, Lorena Pérez-Carrillo, Marta Delgado-Arija, Irene González-Torrent, Roger Vilchez, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 285 (2024)
Heart failure (HF) is a disease related to bioenergetic mitochondrial abnormalities. However, the whole status of molecules involved in the oxidative phosphorylation system (OXPHOS) is unknown. Therefore, we analyzed the OXPHOS transcriptome of human
Externí odkaz:
https://doaj.org/article/4647f54cd85140c2a0e303b44a379907
Autor:
Lorena Pérez-Carrillo, Isaac Giménez-Escamilla, María García-Manzanares, Juan Carlos Triviño, Sandra Feijóo-Bandín, Alana Aragón-Herrera, Francisca Lago, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1337 (2023)
Ischemic cardiomyopathy (ICM) is associated with abnormal microRNA expression levels that involve an altered gene expression profile. However, little is known about the underlying causes of microRNA disruption in ICM and whether microRNA maturation i
Externí odkaz:
https://doaj.org/article/5dc4d9e5dcee4e24984352897a18347d
Autor:
Lorena Pérez-Carrillo, Alana Aragón-Herrera, Isaac Giménez-Escamilla, Marta Delgado-Arija, María García-Manzanares, Laura Anido-Varela, Francisca Lago, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 1996 (2022)
Despite the reduction of cardiovascular events, including the risk of death, associated with sodium/glucose cotransporter 2 inhibitors (SGLT2i), their basic action remains unclear. Sodium/hydrogen exchanger (NHE) has been proposed as the mechanism of
Externí odkaz:
https://doaj.org/article/c73748aac3504694b5fd24e2f692ac2a
Autor:
Estefanía Tarazón, Lorena Pérez-Carrillo, Isaac Giménez-Escamilla, María García-Manzanares, Luis Martínez-Dolz, Manuel Portolés, Esther Roselló-Lletí
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 866 (2022)
A controversial understanding of the state of the DNA methylation machinery exists in ischaemic cardiomyopathy (ICM). Moreover, its relationship to other epigenetic alterations is incomplete. Therefore, we carried out an in-depth study of the DNA met
Externí odkaz:
https://doaj.org/article/146631145e80466f86fb4a2099f916ee
Autor:
Lorena Pérez-Carrillo, Isaac Giménez-Escamilla, Luis Martínez-Dolz, Ignacio José Sánchez-Lázaro, Manuel Portolés, Esther Roselló-Lletí, Estefanía Tarazón
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 135 (2022)
Disturbances in sphingolipid metabolism lead to biological function dysregulation in many diseases, but it has not been described in heart failure (HF). Sphingosine-1-phosphate (S1P) levels have not ever been measured in the myocardium. Therefore, we
Externí odkaz:
https://doaj.org/article/c11bbafd18c54c7490999a64d3b1be30
Autor:
Estefanía Tarazón, Lorena Pérez-Carrillo, Isaac Giménez-Escamilla, Pablo Ramos-Castellanos, Luis Martínez-Dolz, Manuel Portolés, Esther Roselló-Lletí
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1750 (2021)
Although the roles of telomeres and oxidative stress in ischaemic cardiomyopathy (ICM) are known, mechanisms of telomere homeostasis and their relationship with oxidative stress are incompletely understood. We performed two RNA-seq analyses (mRNA n =
Externí odkaz:
https://doaj.org/article/d80e1050f5244168a801b07b6cbb6a09
Autor:
Roselló-Lletí, Lorena Pérez-Carrillo, Isaac Giménez-Escamilla, María García-Manzanares, Juan Carlos Triviño, Sandra Feijóo-Bandín, Alana Aragón-Herrera, Francisca Lago, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther
Publikováno v:
Antioxidants; Volume 12; Issue 7; Pages: 1337
Ischemic cardiomyopathy (ICM) is associated with abnormal microRNA expression levels that involve an altered gene expression profile. However, little is known about the underlying causes of microRNA disruption in ICM and whether microRNA maturation i