Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Lorena M Amaral"'
Autor:
Nathan Campbell, Evangeline Deer, Dylan Solise, Denise C. Cornelius, Ty Turner, Lorena M. Amaral, Owen Herrock, Ariel Jordan, Shivani Shukla, Tarek Ibrahim, Babbette LaMarca
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 4 (2024)
Background Preeclampsia, new‐onset hypertension during pregnancy alongside other organ dysfunction, is the leading cause of mortality for the mother and low birth weight for the baby. Low birth weight contributes to high risk of cardiovascular diso
Externí odkaz:
https://doaj.org/article/bc9482f48b3540708e4f48b304e77a8e
Autor:
Kristin E. Reeve, Evangeline Deer, Lorena M. Amaral, Denise C. Cornelius, Owen Herrock, Ashlyn C. Harmon, Nathan Campbell, Sarah Fitzgerald, Tarek Ibrahim, Gerd Wallukat, Ralf Dechend, Babbette LaMarca
Publikováno v:
Exploration of Medicine, Vol 3, Iss 1, Pp 99-111 (2022)
Aim: Preeclampsia (PE) is a hypertensive disorder of pregnancy associated with activated CD4+ T cells and autoantibodies to angiotensin II type 1 receptor (AT1-AA). We have previously shown that CD4+ T cells isolated from women with PE cause hyperte
Externí odkaz:
https://doaj.org/article/21e8269691c24173b12a14b15a263737
Autor:
Laurent Chatre, Aurélien Ducat, Frank T. Spradley, Ana C. Palei, Christiane Chéreau, Betty Couderc, Kamryn C. Thomas, Anna R. Wilson, Lorena M. Amaral, Irène Gaillard, Céline Méhats, Isabelle Lagoutte, Sébastien Jacques, Francisco Miralles, Frédéric Batteux, Joey P. Granger, Miria Ricchetti, Daniel Vaiman
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102406- (2022)
Preeclampsia (PE) is a high-prevalence pregnancy disease characterized by placental insufficiency, gestational hypertension, and proteinuria. Overexpression of the A isoform of the STOX1 transcription factor (STOX1A) recapitulates PE in mice, and STO
Externí odkaz:
https://doaj.org/article/6fb7acf9dbbc41468dd9af5e74f0699a
Autor:
Mark W. Cunningham, Lorena M. Amaral, Nathan E. Campbell, Denise C. Cornelius, Tarek Ibrahim, Venkata Ramana Vaka, Babbette LaMarca
Publikováno v:
Biology of Sex Differences, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract Two important clinical features of preeclampsia (PE) are hypertension and fetal growth restriction. The reduced uterine perfusion pressure (RUPP) preclinical rat model of PE exhibits both of these features. Moreover, RUPP and PE women have e
Externí odkaz:
https://doaj.org/article/4dc396c7191a4e25abf642238274766b
Autor:
Mark W. Cunningham, Aswathi Jayaram, Evangeline Deer, Lorena M. Amaral, Venkata Ramana Vaka, Tarek Ibrahim, Denise C. Cornelius, Babbette LaMarca
Publikováno v:
Hypertension in Pregnancy, Vol 39, Iss 4, Pp 399-404 (2020)
The RUPP rat model of Preeclampsia exhibits hypertension (MAP), cytolytic natural killer (cNK) cells, tumor necrosis factor alpha (TNF-α) and mitochondrial Reactive Oxygen Species (mt ROS). Objective: Does TNF-α blockade with ETAN (Etanercept) decr
Externí odkaz:
https://doaj.org/article/14cad01b54a040adabb98811b1c1884e
Autor:
Sarah Fitzgerald, Evangeline Deer, James Hogg, Denise C. Cornelius, Ty Turner, Lorena M. Amaral, Ngoc Hoang, Kristin Edwards, Owen Herrock, Nathan Campbell, Tarek Ibrahim, Babbette LaMarca
Publikováno v:
Pregnancy Hypertension. 32:50-56
BACKGROUND Preeclampsia (PE), new-onset hypertension (HTN), and organ dysfunction during the second half of pregnancy, is associated with an increase in inflammatory immune cells, including T helper 17 (Th17) cells. Studies have demonstrated that mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3edc84937af2b8ea5e59f78fbe1f667
https://doi.org/10.1016/j.preghy.2023.04.002
https://doi.org/10.1016/j.preghy.2023.04.002
Autor:
Owen T. Herrock, Evangeline Deer, Lorena M. Amaral, Nathan Campbell, James Lemon, Nicole Ingram, Denise C. Cornelius, Ty W. Turner, Sarah Fitzgerald, Tarek Ibrahim, Ralf Dechend, Gerd Wallukat, Babbette LaMarca
Publikováno v:
American Journal of Physiology-Renal Physiology. 324:F179-F192
This study demonstrates that placental ischemia-stimulated B2 cells induce hypertension and circulating natural killer cell activation and angiotensin II type 1 receptor production in normal pregnant rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::145c20ef2e6036eb93a243daace31232
https://doi.org/10.1152/ajprenal.00190.2022
https://doi.org/10.1152/ajprenal.00190.2022
Autor:
Evangeline Deer, Owen Herrock, Nathan Campbell, Denise Cornelius, Sarah Fitzgerald, Lorena M. Amaral, Babbette LaMarca
Publikováno v:
Nature Reviews Nephrology. 19:257-270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11ae07ea2e173b890c7f6da915ec985f
https://doi.org/10.1038/s41581-022-00670-0
https://doi.org/10.1038/s41581-022-00670-0
Autor:
Evangeline Deer, Lorena M. Amaral, Nathan Campbell, Sarah Fitzgerald, Owen Herrock, Tarek Ibrahim, Babbette LaMarca
Publikováno v:
Cells, Vol 10, Iss 10, p 2797 (2021)
IL-2 is a cytokine released from CD4+T cells with dual actions and can either potentiate the inflammatory response or quell a chronic inflammatory response depending on its circulating concentration. IL-2 is elevated in many chronic inflammatory cond
Externí odkaz:
https://doaj.org/article/0843f3705248410a8834db4fb71f6dfc
Autor:
Evangeline Deer, Jalisa Jones, Denise C. Cornelius, Kyleigh Comley, Owen Herrock, Nathan Campbell, Sarah Fitzgerald, Tarek Ibrahim, Babbette LaMarca, Lorena M. Amaral
Publikováno v:
Cells, Vol 10, Iss 11, p 2817 (2021)
Preeclampsia (PE) is characterized by new onset hypertension in association with placental ischemia, reduced fetal weight, elevated soluble fms-like tyrosine kinase-1 (sFlt-1), and placental mitochondrial (mt) dysfunction and oxidative stress (ROS).
Externí odkaz:
https://doaj.org/article/2dd90e6416b74dd1a0a18ea6cb2c6f3e