Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lorena Fernández-Cabezón"'
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Nowadays steroid manufacturing occupies a prominent place in the pharmaceutical industry with an annual global market over $10 billion. The synthesis of steroidal active pharmaceutical ingredients (APIs) such as sex hormones (estrogens, androgens, an
Externí odkaz:
https://doaj.org/article/95cedfa5b20c4d178da491a8d82ef391
Autor:
Lorena Fernández-Cabezón, Berta Rosich i Bosch, Ekaterina Kozaeva, Nicolás Gurdo, Pablo Iván Nikel
Publikováno v:
Fernández-Cabezón, L, Rosich i Bosch, B, Kozaeva, E, Gurdo, N & Nikel, P I 2022, ' Dynamic flux regulation for high-titer anthranilate production by plasmid-free, conditionally-auxotrophic strains of Pseudomonas putida ', Metabolic Engineering, vol. 73, pp. 11-25 . https://doi.org/10.1016/j.ymben.2022.05.008
Anthranilate, an intermediate of the shikimate pathway, is a high-value aromatic compound widely used as a precursor in the production of dyes, fragrances, plastics and pharmaceuticals. Traditional strategies adopted for microbial anthranilate produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8faaef0802f8d979acca45f1f338627
https://pubmed.ncbi.nlm.nih.gov/35659519
https://pubmed.ncbi.nlm.nih.gov/35659519
Publikováno v:
ACS synthetic biology. 10(5)
The development of complex phenotypes in industrially relevant bacteria is a major goal of metabolic engineering, which encompasses the implementation of both rational and random approaches. In the latter case, several tools have been developed towar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e48e09a09872921b41b3c977c2094b2f
https://pubmed.ncbi.nlm.nih.gov/33843192
https://pubmed.ncbi.nlm.nih.gov/33843192
Publikováno v:
ACS Synthetic Biology
Fernández-Cabezón, L, Cros, A & Nikel, P I 2021, ' Spatiotemporal Manipulation of the Mismatch Repair System of Pseudomonas putida Accelerates Phenotype Emergence ', ACS Synthetic Biology, vol. 10, no. 5, pp. 1214-1226 . https://doi.org/10.1021/acssynbio.1c00031
Fernández-Cabezón, L, Cros, A & Nikel, P I 2021, ' Spatiotemporal Manipulation of the Mismatch Repair System of Pseudomonas putida Accelerates Phenotype Emergence ', ACS Synthetic Biology, vol. 10, no. 5, pp. 1214-1226 . https://doi.org/10.1021/acssynbio.1c00031
Developing complex phenotypes in industrially-relevant bacteria is a major goal of metabolic engineering, which encompasses the implementation of both rational and random approaches. In the latter case, several tools have been developed towards incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30768d38daaf2e44ef67c9a574590825
https://doi.org/10.1101/2021.01.21.427673
https://doi.org/10.1101/2021.01.21.427673
Autor:
Usama Bilal Anwar, Brahim Benyahia, Roberta Bernini, Arthur D. Boyarov, Larissa Pereira Brumano, B.A. Caetano, R. Coppola, J.M. Cruz, A.G. da Cruz, V. De Feo, Ana Olívia de Souza, A. d’Acierno, Marco Esti, Lorena Fernández-Cabezón, F. Fratianni, C. Henrique, Manfred Kircher, Katia Liburdi, D. Luz, Rafael Marques-Porto, T. Mitsunari, A. Moldes, D.D. Munhoz, F. Nazzaro, Guilherme Tonial Neves, Pablo I. Nikel, Alina Osmakova, Adalberto Pessoa, R.M.F. Piazza, M. Rincón-Fontán, Alexandre Gomes Rodrigues, L. Rodríguez-López, Celso Santi, Francisco Vitor Santos da Silva, X. Vecino, Valerie C.A. Ward, Ingrid Padovese Zwar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9348c340af4860a8d2b2c964c5d97aab
https://doi.org/10.1016/b978-0-444-64301-8.00018-4
https://doi.org/10.1016/b978-0-444-64301-8.00018-4
Contemporary society faces multiple challenges, such as the rapidly growing human population and climate change, which require the urgent adoption of smart solutions leading to enhanced sustainability. The use of novel and innovative technologies, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32e3af31fda8ca7140631254fe393dfb
https://doi.org/10.1016/b978-0-444-64301-8.00011-1
https://doi.org/10.1016/b978-0-444-64301-8.00011-1
Publikováno v:
Environmental Microbiology. 20:1815-1827
In this work, we have characterized the C-19+ gene cluster (MSMEG_2851 to MSMEG_2901) of Mycobacterium smegmatis. By in silico analysis, we have identified the genes encoding enzymes involved in the modification of the A/B steroid rings during the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07244c87cb4e25fa152037a5d8627339
https://doi.org/10.1111/1462-2920.14114
https://doi.org/10.1111/1462-2920.14114
Publikováno v:
Environmental Microbiology. 19:2546-2563
The C-19 steroids 4-androstene-3,17-dione (AD), 1,4-androstadiene-3,17-dione (ADD) or 9α-hydroxy-4-androstene-3,17-dione (9OH-AD), which have been postulated as intermediates of the cholesterol catabolic pathway in Mycobacterium smegmatis, cannot be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5dc7116f13ff7ba1df133eaf6d6b899
https://doi.org/10.1111/1462-2920.13704
https://doi.org/10.1111/1462-2920.13704
Publikováno v:
Metabolic Engineering
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Sánchez-Pascuala, A, Fernandez-Cabezon, L, de Lorenzo, V & Nikel, P I 2019, ' Functional implementation of a linear glycolysis for sugar catabolism in Pseudomonas putida ', Metabolic Engineering, vol. 54, pp. 200-211 . https://doi.org/10.1016/j.ymben.2019.04.005
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Sánchez-Pascuala, A, Fernandez-Cabezon, L, de Lorenzo, V & Nikel, P I 2019, ' Functional implementation of a linear glycolysis for sugar catabolism in Pseudomonas putida ', Metabolic Engineering, vol. 54, pp. 200-211 . https://doi.org/10.1016/j.ymben.2019.04.005
Digital.CSIC. Repositorio Institucional del CSIC
instname
The core metabolism for glucose assimilation of the soil bacterium and platform strain Pseudomonas putida KT2440 has been reshaped from the native, cyclically-operating Entner-Doudoroff (ED) pathway to a linear Embden-Meyerhof-Parnas (EMP) glycolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a84d5e2a2255c06db60e4432533a18
http://hdl.handle.net/10261/240363
http://hdl.handle.net/10261/240363
Autor:
Carmen Felpeto-Santero, José Luis García, Julia García-Fernández, Lorena Fernández-Cabezón, Beatriz Galán
Publikováno v:
Aerobic Utilization of Hydrocarbons, Oils and Lipids ISBN: 9783319397825
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89029f08503627aa13c3e59ffde3798a
https://doi.org/10.1007/978-3-319-50418-6_43
https://doi.org/10.1007/978-3-319-50418-6_43