Výsledky vyhledávání - "Lorena Di Lisio"

The Evx1/Evx1as gene locus regulates anterior-posterior patterning during gastrulation

Autor: Kevin R. Gillinder, Marcel E. Dinger, Michael R. Tallack, Lorena Di Lisio, Paulo P. Amaral, Andrew C. Perkins, Joanna Crawford, Charles C. Bell, Anton M.F. Kalsbeek, Franziska Gruhl, Graham Magor, Pierre Tangermann, Jessica E. Frith, John S. Mattick, Seth W. Cheetham, Kelin Ru

Publikováno v: Scientific Reports

Thousands of sense-antisense mRNA-lncRNA gene pairs occur in the mammalian genome. While there is usually little doubt about the function of the coding transcript, the function of the lncRNA partner is mostly untested. Here we examine the function of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12a143f09080c5152c55b5d9500b05f
https://doi.org/10.1038/srep26657

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The role of miRNAs in the pathogenesis and diagnosis of B-cell lymphomas

Autor: Miguel A. Piris, Nerea Martinez, Lorena Di Lisio, Margarita Sánchez-Beato, Santiago Montes-Moreno, Miguel Piris-Villaespesa

Publikováno v: Blood. 120:1782-1790

There is a demand to understand B-cell lymphoma pathogenesis better, to identify new markers, and to define multiple lymphoproliferative disorders more accurately. MicroRNAs (miRNAs) are regulators of protein translation, comprising a group of more t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117cd7452039de4c85ba06e49af4dec4
https://doi.org/10.1182/blood-2012-05-402784

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Epstein-Barr virus microRNAs repress BCL6 expression in diffuse large B-cell lymphoma

Autor: David G. Pisano, R Rodríguez, Santiago Montes-Moreno, Margarita Sánchez-Beato, Pierfrancesco Vargiu, Manuela Mollejo, M A Piris, Lorena Di Lisio, Daniel Martín-Pérez, Josep Castellví, Nerea Martinez, Eduardo Andres Leon, S M Rodríguez-Pinilla

Publikováno v: Leukemia. 26:180-183

Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma, accounting for 30–40% of all newly diagnosed lymphomas. DLBCL is considered a heterogeneous disease, with some specific clinicopathological variants of DLBCLs being associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326d49d203bf229939ed6bce24e2a8c7
https://doi.org/10.1038/leu.2011.189

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NF-κB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas

Autor: Javier Rodríguez-Ubreva, Esteban Ballestar, Henar Hernando, Claire Shannon-Lowe, Roser Vento-Tormo, Miguel A. Piris, Nerea Martinez, Jose Urquiza, Lorena Di Lisio, Abul B. M. M. K. Islam, Santiago Montes-Moreno, Nuria Lopez-Bigas

Publikováno v: Nucleic Acids Research
Recercat. Dipósit de la Recerca de Catalunya
instname
Nucleic Acids Res (2014) 42 (17): 11025-11039.
Dipòsit Digital de la UB
Universidad de Barcelona
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

MicroRNAs (miRNAs) have negative effects on gene expression and are major players in cell function in normal and pathological conditions. Epstein-Barr virus (EBV) infection of resting B lymphocytes results in their growth transformation and associate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1cbdbd4fd14cfca37c71cd75bb33a3
https://pubmed.ncbi.nlm.nih.gov/25200074

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miR-217 is an oncogene that enhances the germinal center reaction

Autor: Marta Cañamero, Rubén Nogales-Cadenas, Almudena R. Ramiro, Nahikari Bartolomé-Izquierdo, Virginia G. de Yébenes, Miguel A. Piris, Nerea Martinez, Lorena Di Lisio, Pablo Pérez-Durán, Sonia M. Mur, Davide F. Robbiani, Alberto Pascual-Montano

Publikováno v: Blood

microRNAs are a class of regulators of gene expression that have been shown critical for a great number of biological processes; however, little is known of their role in germinal center (GC) B cells. Although the GC reaction is crucial to ensure a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c314e3cef4c195fc9faaf2118ec4b17d

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Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway

Autor: Maria J. Bueno, Lorena Di Lisio, Ignacio Pérez de Castro, Ruth Sánchez-Martínez, Miguel A. Piris, Javier Santos, Santiago Montes-Moreno, Marta Gómez de Cedrón, Manuel Guerrero, Gonzalo Gómez-López, David G. Pisano, Marcos Malumbres, José Fernández-Piqueras, Nerea Martinez

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Blood; Vol 117

Many mammalian transcripts contain target sites for multiple miRNAs although it is not clear to what extent miRNAs may coordinately regulate single genes. We have mapped the interactions between downregulated miRNAs and overexpressed target protein-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ac5ec022fcd5240c8be3675061ed6b
https://pubmed.ncbi.nlm.nih.gov/21478429

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Deregulated expression of the polycomb-group protein SUZ12 target genes characterizes mantle cell lymphoma

Autor: Esther María Sánchez Sánchez, Miguel A. Piris, Margarita Sánchez-Beato, Javier Suela, Lorena Di Lisio, Nerea Martinez, Javier Alves, Pierfrancesco Vargiu, Lorena Maestre, Daniel Martín-Pérez

Publikováno v: The American journal of pathology. 177(2)

Polycomb proteins are known to be of great importance in human cancer pathogenesis. SUZ12 is a component of the Polycomb PRC2 complex that, along with EZH2, is involved in embryonic stem cell differentiation. EZH2 plays an essential role in many canc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f25709fa1478110a85b5b39bd636e0
https://pubmed.ncbi.nlm.nih.gov/20558579

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The Epstein Barr-encoded BART-6-3p microRNA affects regulation of cell growth and immuno response in Burkitt lymphoma

Autor: Lorenzo Leoncini, Stefano Lazzi, Cristina Ulivieri, Anna Onnis, Mohsen Navari, Lucia Mundo, Giulia De Falco, Lorena Di Lisio, Eduardo Andres Leon, Maria Raffaella Ambrosio, Gonzalo Gomez, Miguel A. Piris, Sara Gazaneo

Publikováno v: Infectious Agents and Cancer

Background: Burkitt lymphoma is an aggressive B-cell lymphoma presenting in three clinical forms: endemic, sporadic and immunodeficiency-associated. More than 90% of endemic Burkitt lymphoma carry latent Epstein-Barr virus, whereas only 20% of sporad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d64aeda9c3651459323902ab165b0f
http://europepmc.org/articles/PMC4005456

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