Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lorena Carvelli"'
Autor:
Andrea Carolina Aguilera, Natalia Leiva, Pablo Ariel Alvarez, Georgina Pulcini, Laura Lucía Pereyra, Carlos Ramón Morales, Miguel Ángel Sosa, Lorena Carvelli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The selective transport to lysosomes can be mediated by either mannose-6-phosphate receptors (CD-MPR and CI-MPR) or sortilin. In mammalian epididymis, some lysosomal proteins are secreted into the lumen through unknown mechanisms. To investi
Externí odkaz:
https://doaj.org/article/4af0af75f52e4d938fac44bf31307ead
Autor:
Andrea Carolina Aguilera, Natalia Leiva, Pablo Ariel Alvarez, Georgina Pulcini, Laura Lucía Pereyra, Carlos Ramón Morales, Miguel Ángel Sosa, Lorena Carvelli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/e9790e95a43c45b99b3e8fbf0b05e1e3
Autor:
Lorena Carvelli, Louis Hermo, Cristian O’Flaherty, Richard Oko, Alexey V. Pshezhetsky, Carlos R. Morales
Publikováno v:
PLoS ONE, Vol 18, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/2f5ce54c8db64669a1f8eb066c38c4ef
Autor:
Lorena Carvelli, Andrea Carolina Aguilera, Leila Zyla, Laura Lucía Pereyra, Carlos R Morales, Louis Hermo, Miguel A Sosa
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250454 (2021)
In the epididymis, lysosomal proteins of the epithelial cells are normally targeted from the Golgi apparatus to lysosomes for degradation, although their secretion into the epididymal lumen has been documented and associated with sperm maturation. In
Externí odkaz:
https://doaj.org/article/5513e4fbf10249bea2e8f66143010732
Autor:
Carlos R. Morales, Andrea C. Aguilera, Laura Lucía Pereyra, Leila Zyla, Miguel A. Sosa, Lorena Carvelli, Louis Hermo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0250454 (2021)
PLoS ONE, Vol 16, Iss 4, p e0250454 (2021)
In the epididymis, lysosomal proteins of the epithelial cells are normally targeted from the Golgi apparatus to lysosomes for degradation, although their secretion into the epididymal lumen has been documented and associated with sperm maturation. In
Publikováno v:
Journal of Cellular Biochemistry. 117:2464-2472
Glycosidases may play a role in sperm maturation during epididymal transit. In this work, we describe the interaction of these enzymes with bull spermatozoa. We found that β-galactosidase associated to spermatozoa can be released under low ionic str
Autor:
Lorena, Carvelli, Yuan, Libin, Sherry, Esfandnia, Yan, Zhang, John F, Presley, Carlos R, Morales
Publikováno v:
Histology and histopathology. 32(10)
A number of pathogens for which there are no effective treatments infect the cells via endocytosis. Once in the endosomes, the pathogens complete their life cycle by overriding normal lysosomal functions. Recently, our laboratory identified the lysos
Publikováno v:
Andrologia. 46:224-230
The mammalian epididymis plays a role in sperm maturation through its secretory activity. Among the proteins secreted by the epithelium, there are significant amounts of acid hydrolases. In most cell types, the normal distribution of lysosomal enzyme
Publikováno v:
Journal of Cellular Biochemistry. 110:1101-1110
It is believed that the mammalian epididymis participates in the maturation of the sperm due to its secretory activity. High concentrations of several secreted acid hydrolases are found in the epididymal lumen. Moreover, some of these enzymes are sec
Autor:
Guillermo Jofré, T. Sartor, Lorena Carvelli, Valeria Balmaceda, Miguel A. Gama Sosa, Patricia Barrera
Publikováno v:
Cells Tissues Organs. 190:27-33
The significance of the coexistence of 2 mannose-6-phosphate receptors (MPRs) in most cell types still remains poorly understood. In this study, expression of the cation-dependent MPR (CD-MPR) and the cation-independent MPR (CI-MPR) was measured by W