Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Lorena, Maestre"'
Autor:
Giovanna Roncador, Joan Puñet-Ortiz, Lorena Maestre, Luis Gerardo Rodríguez-Lobato, Scherezade Jiménez, Ana Isabel Reyes-García, Álvaro García-González, Juan F. García, Miguel Ángel Piris, Santiago Montes-Moreno, Manuel Rodríguez-Justo, Mari-Pau Mena, Carlos Fernández de Larrea, Pablo Engel
Publikováno v:
Cancers, Vol 14, Iss 9, p 2154 (2022)
CD229 (Ly9) homophilic receptor, which belongs to the SLAM family of cell-surface molecules, is predominantly expressed on B and T cells. It acts as a signaling molecule, regulating lymphocyte homoeostasis and activation. Studies of CD229 function in
Externí odkaz:
https://doaj.org/article/8651174ff58d4555a2735c6faf06f5cd
Autor:
Lorena Maestre, Juan Fernando García-García, Scherezade Jiménez, Ana Isabel Reyes-García, Álvaro García-González, Santiago Montes-Moreno, Alberto J Arribas, Patricia González-García, Eduardo Caleiras, Alison H Banham, Miguel Ángel Piris, Giovanna Roncador
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229743 (2020)
Thymocyte selection-associated high-mobility group box (TOX) is a DNA-binding factor that is able to regulate transcription by modifying local chromatin structure and modulating the formation of multi-protein complexes. TOX has multiple roles in the
Externí odkaz:
https://doaj.org/article/8c35e2e4880144ceb30e9bb7209f0a7f
Autor:
Eva Pérez-Guijarro, Panagiotis Karras, Metehan Cifdaloz, Raúl Martínez-Herranz, Estela Cañón, Osvaldo Graña, Celia Horcajada-Reales, Direna Alonso-Curbelo, Tonantzin G. Calvo, Gonzalo Gómez-López, Nicolas Bellora, Erica Riveiro-Falkenbach, Pablo L. Ortiz-Romero, José L. Rodríguez-Peralto, Lorena Maestre, Giovanna Roncador, Juan C. de Agustín Asensio, Colin R. Goding, Eduardo Eyras, Diego Megías, Raúl Méndez, María S. Soengas
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Cytoplasmic polyadenylated transcripts have been poorly characterized, particularly in cancer. Here the authors identify a lineage-specific requirement of the cytoplasmic polyadenylation binding protein 4 (CPEB4) in malignant melanoma and show that i
Externí odkaz:
https://doaj.org/article/4fec995c232548e9812db54cfb254079
Autor:
Alberto Cascón, Mercedes Robledo, Graeme Eisenhofer, Jorgina Satrústegui, Manel Esteller, Sebastian Moran, Lorena Maestre, Scherezade Jiménez, Emiliano Honrado, Rafael Torres-Pérez, Antonio Galarreta, Rocío Letón, Guillermo Pita, María Currás-Freixes, Laura Contreras, Susan Richter, Iñaki Comino-Méndez, Laura Remacha
(A) GOT2 western blot of HeLa cells stably silenced for GOT2 expression by shRNA transfection compared to non-silenced scrambled (Scr) control cells. β-actin was used as a loading control. (B) Number of GOT2 KD HeLa cells after transfection with emp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b90cd8afdd8bbe93155ae3e62b7102
https://doi.org/10.1158/1078-0432.22463502.v1
https://doi.org/10.1158/1078-0432.22463502.v1
Autor:
Alberto Cascón, Mercedes Robledo, Graeme Eisenhofer, Jorgina Satrústegui, Manel Esteller, Sebastian Moran, Lorena Maestre, Scherezade Jiménez, Emiliano Honrado, Rafael Torres-Pérez, Antonio Galarreta, Rocío Letón, Guillermo Pita, María Currás-Freixes, Laura Contreras, Susan Richter, Iñaki Comino-Méndez, Laura Remacha
Genes included in the targeted next-generation sequencing panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e98eb7e3ea8f554aaa2b164e070da88
https://doi.org/10.1158/1078-0432.22463493
https://doi.org/10.1158/1078-0432.22463493
Autor:
Alberto Cascón, Mercedes Robledo, Graeme Eisenhofer, Jorgina Satrústegui, Manel Esteller, Sebastian Moran, Lorena Maestre, Scherezade Jiménez, Emiliano Honrado, Rafael Torres-Pérez, Antonio Galarreta, Rocío Letón, Guillermo Pita, María Currás-Freixes, Laura Contreras, Susan Richter, Iñaki Comino-Méndez, Laura Remacha
Legends of the Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2396b3dc61f5ff1932172270f84d7b
https://doi.org/10.1158/1078-0432.22463508.v1
https://doi.org/10.1158/1078-0432.22463508.v1
Autor:
Alberto Cascón, Mercedes Robledo, Graeme Eisenhofer, Jorgina Satrústegui, Manel Esteller, Sebastian Moran, Lorena Maestre, Scherezade Jiménez, Emiliano Honrado, Rafael Torres-Pérez, Antonio Galarreta, Rocío Letón, Guillermo Pita, María Currás-Freixes, Laura Contreras, Susan Richter, Iñaki Comino-Méndez, Laura Remacha
Purpose: Mutations in Krebs cycle genes are frequently found in patients with pheochromocytomas/paragangliomas. Disruption of SDH, FH or MDH2 enzymatic activities lead to accumulation of specific metabolites, which give rise to epigenetic changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ff82b4b4e311b0bdcde2d724f003d6
https://doi.org/10.1158/1078-0432.c.6525420
https://doi.org/10.1158/1078-0432.c.6525420
Autor:
Sara, Fernández, Jose L, Solórzano, Eva, Díaz, Victoria, Menéndez, Lorena, Maestre, Sara, Palacios, Mar, López, Argentina Colmenero, Velázquez, Mónica, Estévez, Carlos, Montalban, Angel, Martinez-Ramirez, Giovanna, Roncador, Juan F, García
Publikováno v:
Blood Advances.
Constitutive activation of the JAK/STAT pathway is a common phenomenon in classic Hodgkin lymphoma (cHL). The clinical potential of anti-JAK/STAT therapy is being explored in early-stage clinical trials. Notwithstanding, very little information is av
Autor:
Ana M Martín-Moreno, Giovanna Roncador, Lorena Maestre, Elena Mata, Scherezade Jiménez, Jorge L Martínez-Torrecuadrada, Ana I Reyes-García, Carmen Rubio, José F Tomás, Mónica Estévez, Karen Pulford, Miguel A Piris, Juan F García
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0125203 (2015)
Tumour-associated macrophages (TAMs) have been associated with survival in classic Hodgkin lymphoma (cHL) and other lymphoma types. The maturation and differentiation of tissue macrophages depends upon interactions between colony-stimulating factor 1
Externí odkaz:
https://doaj.org/article/bbc7d5de086f415f89566775f74440c4
Autor:
Gromoslaw A. Smolen, Marcos Lahera, Raúl M. Luque, Rocío Letón, Graeme Eisenhofer, Lorena Maestre, Miguel Urioste, Javier Aller, Cristina Moreno-Rengel, Rafael Torres-Pérez, María Ángeles Gálvez, Giovanni Cianchetta, Belen Herraez, Javier Coloma, Emiliano Honrado, Maria Currás-Freixes, Christopher E. Mahoney, Bruna Calsina, Susan Richter, Laura Remacha, Mercedes Robledo, Oscar Llorca, Óscar García-Uriarte, David Pirman, Guillermo Pita, Cristina Rodríguez-Antona, Cristina Montero-Conde, Alberto Cascón
Publikováno v:
The American Journal of Human Genetics. 104:651-664
Pheochromocytomas and paragangliomas (PPGLs) provide some of the clearest genetic evidence for the critical role of metabolism in the tumorigenesis process. Approximately 40% of PPGLs are caused by driver germline mutations in 16 known susceptibility