Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Lorena, Donnici"'
Autor:
Valeria Fumagalli, Pietro Di Lucia, Micol Ravà, Davide Marotta, Elisa Bono, Stefano Grassi, Lorena Donnici, Rolando Cannalire, Irina Stefanelli, Anastasia Ferraro, Francesca Esposito, Elena Pariani, Donato Inverso, Camilla Montesano, Serena Delbue, Stanley Perlman, Enzo Tramontano, Raffaele De Francesco, Vincenzo Summa, Luca G Guidotti, Matteo Iannacone
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-13 (2023)
Abstract Alongside vaccines, antiviral drugs are becoming an integral part of our response to the SARS‐CoV‐2 pandemic. Nirmatrelvir—an orally available inhibitor of the 3‐chymotrypsin‐like cysteine protease—has been shown to reduce the ri
Externí odkaz:
https://doaj.org/article/af6a4cf2e9764395b79666f9ed74a291
Autor:
Emanuele Andreano, Ida Paciello, Giulio Pierleoni, Giulia Piccini, Valentina Abbiento, Giada Antonelli, Piero Pileri, Noemi Manganaro, Elisa Pantano, Giuseppe Maccari, Silvia Marchese, Lorena Donnici, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Concetta De Santi, Massimiliano Fabbiani, Ilaria Rancan, Mario Tumbarello, Francesca Montagnani, Claudia Sala, Duccio Medini, Raffaele De Francesco, Emanuele Montomoli, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
SARS-CoV-2 vaccines and infection induce antibody responses but the evolution of subsequent variants has resulted in the development of escape mutants. Here the authors characterise, at single cell level, the antibody response in donors after a third
Externí odkaz:
https://doaj.org/article/8bf9f127c9594148a4055cebaa03c05d
Autor:
Emanuela D’Acunto, Alessia Muzi, Silvia Marchese, Lorena Donnici, Valerio Chiarini, Federica Bucci, Emiliano Pavoni, Fabiana Fosca Ferrara, Manuela Cappelletti, Roberto Arriga, Silvia Maria Serrao, Valentina Peluzzi, Eugenia Principato, Mirco Compagnone, Eleonora Pinto, Laura Luberto, Daniela Stoppoloni, Armin Lahm, Rüdiger Groß, Alina Seidel, Lukas Wettstein, Jan Münch, Andrew Goodhead, Judicael Parisot, Raffaele De Francesco, Gennaro Ciliberto, Emanuele Marra, Luigi Aurisicchio, Giuseppe Roscilli
Publikováno v:
Antibodies, Vol 13, Iss 1, p 5 (2024)
The COVID-19 pandemic, once a global crisis, is now largely under control, a testament to the extraordinary global efforts involving vaccination and public health measures. However, the relentless evolution of SARS-CoV-2, leading to the emergence of
Externí odkaz:
https://doaj.org/article/c7871d373abc48969226325b103c6a9c
Autor:
Emanuele Andreano, Ida Paciello, Silvia Marchese, Lorena Donnici, Giulio Pierleoni, Giulia Piccini, Noemi Manganaro, Elisa Pantano, Valentina Abbiento, Piero Pileri, Linda Benincasa, Ginevra Giglioli, Margherita Leonardi, Piet Maes, Concetta De Santi, Claudia Sala, Emanuele Montomoli, Raffaele De Francesco, Rino Rappuoli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Here, Andreano and Paciello et al. show, at single cell level, the functional and genetic characteristics underlying the Omicron BA.1 and BA.2 cross-protective antibody response in naïve and previously infected COVID-19 vaccinees.
Externí odkaz:
https://doaj.org/article/f6ef68614439432b9c2c0fa9a78d436d
Autor:
Annarita Miluzio, Alessandro Cuomo, Chiara Cordiglieri, Lorena Donnici, Elisa Pesce, Mauro Bombaci, Matteo Conti, Alessandra Fasciani, Luigi Terracciano, Lara Manganaro, Mirco Toccafondi, Alessandra Scagliola, Stefania Oliveto, Sara Ricciardi, Renata Grifantini, Raffaele De Francesco, Sergio Abrignani, Nicola Manfrini, Stefano Biffo
Publikováno v:
EBioMedicine, Vol 87, Iss , Pp 104390- (2023)
Summary: Background: The COVID-19 pandemic is an infectious disease caused by SARS-CoV-2. The first step of SARS-CoV-2 infection is the recognition of angiotensin-converting enzyme 2 (ACE2) receptors by the receptor-binding domain (RBD) of the viral
Externí odkaz:
https://doaj.org/article/607fc0df62fb49a49aba800f71f5b850
Autor:
Cristina Cheroni, Lara Manganaro, Lorena Donnici, Valeria Bevilacqua, Raoul J. P. Bonnal, Riccardo L. Rossi, Raffaele De Francesco
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Interferons (IFNs) are key cytokines involved in alerting the immune system to viral infection. After IFN stimulation, cellular transcriptional profile critically changes, leading to the expression of several IFN stimulated genes (ISGs) that
Externí odkaz:
https://doaj.org/article/e7ea4f5c876b42c19f3dfa4679c5eca3
Autor:
Andrea Favalli, Ennio Giulio Favalli, Andrea Gobbini, Elena Zagato, Mauro Bombaci, Gabriella Maioli, Elisa Pesce, Lorena Donnici, Paola Gruarin, Martina Biggioggero, Serena Curti, Lara Manganaro, Edoardo Marchisio, Valeria Bevilacqua, Martina Martinovic, Tanya Fabbris, Maria Lucia Sarnicola, Mariacristina Crosti, Laura Marongiu, Francesca Granucci, Samuele Notarbartolo, Alessandra Bandera, Andrea Gori, Raffaele De Francesco, Sergio Abrignani, Roberto Caporali, Renata Grifantini
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 has proven to be particularly serious and life-threatening for patients presenting with pre-existing pathologies. Patients affected by rheumatic musculoskeletal disease (RMD) are likely to have impaired immune responses against SARS-CoV-2 in
Externí odkaz:
https://doaj.org/article/7b3ac083ac43439fb43f924515085e54
Autor:
Oscar Francesconi, Lorena Donnici, Marco Fragai, Elisa Pesce, Mauro Bombaci, Alessandra Fasciani, Lara Manganaro, Matteo Conti, Renata Grifantini, Raffaele De Francesco, Cristina Nativi, Stefano Roelens
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104239- (2022)
Summary: Developing strategies against the SARS-CoV-2 is currently a main research subject. SARS-CoV-2 infects host cells by binding to human ACE2 receptors. Both, virus and ACE2, are highly glycosylated, and exploiting glycans of the SARS-CoV-2 enve
Externí odkaz:
https://doaj.org/article/714c1c36152045e78a22d088d37e8025
Autor:
Andrea Lombardi, Giacomo M. Butta, Lorena Donnici, Giorgio Bozzi, Massimo Oggioni, Patrizia Bono, Malvina Matera, Dario Consonni, Serena Ludovisi, Antonio Muscatello, Ferruccio Ceriotti, Matteo Conti, Susanna Scaglioni, Greta Gallo, Edoardo Scarpa, Michael Letko, Sergio Abrignani, Renata Grifantini, Raffaele De Francesco, Andrea Gori, Lara Manganaro, Alessandra Bandera
Publikováno v:
The Lancet Regional Health. Europe, Vol 13, Iss , Pp 100287- (2022)
Summary: Background: Vaccines against COVID-19 are a powerful tool to control the current SARS-CoV-2 pandemic. A thorough description of their immunogenicity among people living with HIV (PLWHIV) is necessary. We aimed to assess the immunogenicity of
Externí odkaz:
https://doaj.org/article/84fed7bfb6fa49dbab84ce3ade23cb9d
Autor:
Cristina Cheroni, Lara Manganaro, Lorena Donnici, Valeria Bevilacqua, Raoul J. P. Bonnal, Riccardo L. Rossi, Raffaele De Francesco
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/1847a8a6c64b4bfa9bb8be97bc79c73c