Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Loren M. DeVito"'
Autor:
Loren M, DeVito, Edward A, Dennis, Barbara B, Kahn, Gerald I, Shulman, Joseph L, Witztum, Sudeshna, Sadhu, Joseph, Nickels, Matthew, Spite, Susan, Smyth, Sarah, Spiegel
Publikováno v:
Ann N Y Acad Sci
Recent research has shed light on the cellular and molecular functions of bioactive lipids that go far beyond what was known about their role as dietary lipids. Bioactive lipids regulate inflammation and its resolution as signaling molecules. Genetic
Autor:
Morgan E. Levine, Judith Campisi, Mitzi M. Gonzales, James L. Kirkland, Nir Barzilai, George A. Kuchel, Ana Maria Cuervo, Laura J. Niedernhofer, Luigi Ferrucci, Daniel E. L. Promislow, Loren M. DeVito, Joan B. Mannick, Pinchas Cohen, Jamie N. Justice, Sofiya Milman
Publikováno v:
Ann N Y Acad Sci
For many years, it was believed that the aging process was inevitable and that age-related diseases could not be prevented or reversed. The geroscience hypothesis, however, posits that aging is, in fact, malleable and, by targeting the hallmarks of b
Autor:
Roseann F. Titcombe, Edward B. Ziff, Shannon O. Antoine, Sinedu Abera, David S. Tukey, Loren M. DeVito, Charles A. Hoeffer, Sarah A. Vunck, Yoon Choi, Natasha N. Tirko, Franz Hofmann, Charlotte M. Wincott
Publikováno v:
Neurobiology of Learning and Memory. 114:32-39
Neuronal activity regulates AMPA receptor trafficking, a process that mediates changes in synaptic strength, a key component of learning and memory. This form of plasticity may be induced by stimulation of the NMDA receptor which, among its activitie
Autor:
Howard Eichenbaum, Loren M. DeVito
Publikováno v:
The Journal of Neuroscience. 31:3169-3175
Episodic memory involves remembering the incidental order of a series of events that comprise a specific experience. Current models of temporal organization in episodic memory have demonstrated that animals can make memory judgments about the order o
Autor:
Joseph T. Coyle, Howard Eichenbaum, Darrick T. Balu, Alo C. Basu, Loren M. DeVito, Benjamin R. Kanter, Christine Lykken
Publikováno v:
Genes, Brain and Behavior. 10:210-222
There is substantial evidence implicating N-methyl-d-aspartate receptors (NMDARs) in memory and cognition. It has also been suggested that NMDAR hypofunction might underlie the cognitive deficits observed in schizophrenia since morphological changes,
Publikováno v:
Learning & Memory. 17:161-167
“Transitive inference” refers to the ability to judge from memory the relationships between indirectly related items that compose a hierarchically organized series, and this capacity is considered a fundamental feature of relational memory. Here
Publikováno v:
Chemical Senses. 31:343-349
Behavior genetics studies in mice demand efficient training protocols for rapid phenotypic screening. However, the capacity of neonatal mice to form and retain associative memories has been difficult to study due to their limited sensorimotor capacit
Autor:
Edward B. Ziff, Seonil Kim, Franz Hofmann, Charles A. Hoeffer, David S. Tukey, Loren M. DeVito, Hiwot K. Girma, Roseann F. Titcombe, Joseph Pick, Charlotte M. Wincott
Activity-dependent trafficking of AMPA receptors to synapses regulates synaptic strength. Activation of the NMDA receptor induces several second messenger pathways that contribute to receptor trafficking-dependent plasticity, including the NO pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145b9853d81ec3922b8f867f0dd8598a
https://europepmc.org/articles/PMC3541678/
https://europepmc.org/articles/PMC3541678/
Autor:
Scellig S D Stone, Loren M. DeVito, Sheena A. Josselyn, Andres M. Lozano, Cátia M. Teixeira, Kirill Zaslavsky, Paul W. Frankland
Deep brain stimulation (DBS) is an established therapeutic modality for the treatment of movement disorders and an emerging therapeutic approach for the treatment of disorders of mood and thought. For example, recently we have shown that DBS of the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae389350edb94dfb2b5f05cc7a5df32
https://europepmc.org/articles/PMC6623309/
https://europepmc.org/articles/PMC6623309/
Autor:
Ling He, Loren M. DeVito, Paul W. Frankland, Jing Wang, Freda D. Miller, Gordon Keller, Gonzalo I. Cancino, David Tsui, David L. Kaplan, Denis Gallagher
Publikováno v:
Cell stem cell. 11(1)
SummaryAlthough endogenous recruitment of adult neural stem cells has been proposed as a therapeutic strategy, clinical approaches for achieving this are lacking. Here, we show that metformin, a widely used drug, promotes neurogenesis and enhances sp