Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Loren H. Parsons"'
Autor:
Francisco Javier Pavón, Ilham Y. Polis, David G. Stouffer, Benjamin F. Cravatt, Marisa Roberto, Rémi Martin-Fardon, Fernando Rodríguez de Fonseca, Loren H. Parsons, Antonia Serrano
Publikováno v:
Neurobiology of Stress, Vol 14, Iss , Pp 100293- (2021)
The endocannabinoid system is involved in the regulation of the stress response, but the relative contribution of N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG) and their mechanisms have to be elucidated. In this study, we compare
Externí odkaz:
https://doaj.org/article/4542b0d0ad604fae857eff5eded83f6b
Autor:
Francisco Javier Pavón, Antonia Serrano, Rémi Martin-Fardon, Loren H. Parsons, Fernando Rodríguez de Fonseca, David G. Stouffer, Ilham Polis, Marisa Roberto
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Ethanol (EtOH) self-administration is particularly sensitive to the modulation of CB(1) signaling in the nucleus accumbens (NAc) shell, and EtOH consumption increases extracellular levels of the endogenous cannabinoid CB(1) receptor agoni
Autor:
Benjamin F. Cravatt, David G. Stouffer, Marisa Roberto, Ilham Polis, Rémi Martin-Fardon, Loren H. Parsons, Antonia Serrano, Francisco Javier Pavón, Fernando Rodríguez de Fonseca
Publikováno v:
Neurobiology of Stress
Neurobiology of Stress, Vol 14, Iss, Pp 100293-(2021)
Neurobiology of Stress, Vol 14, Iss, Pp 100293-(2021)
The endocannabinoid system is involved in the regulation of the stress response, but the relative contribution of N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG) and their mechanisms have to be elucidated. In this study, we compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1136f4b77fb6282ae93751d3737c6301
https://hdl.handle.net/10668/3827
https://hdl.handle.net/10668/3827
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109948 (2014)
Impaired cognitive processing is a hallmark of addiction. In particular, deficits in inhibitory control can propel continued drug use despite adverse consequences. Clinical evidence shows that detoxified alcoholics exhibit poor inhibitory control in
Externí odkaz:
https://doaj.org/article/11c65e4074dc456284fcf5729b621c8a
Autor:
Matthew W. Buczynski, Harpreet Sidhu, Abigail E. Agoglia, Marisa Roberto, Rose Ying, Sarah A. Wolfe, Melissa A. Herman, Luis A. Natividad, Candice Contet, Loren H. Parsons, Manhua Zhu
Publikováno v:
eNeuro
The lateral amygdala (LA) serves as the point of entry for sensory information within the amygdala complex, a structure that plays a critical role in emotional processes and has been implicated in alcohol use disorders. Within the amygdala, the corti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8146821f4dbe590d969ac5636c65c124
https://hdl.handle.net/10919/98248
https://hdl.handle.net/10919/98248
Autor:
M Jerry Wright, Deepshikha Angrish, Shawn M Aarde, Deborah J Barlow, Matthew W Buczynski, Kevin M Creehan, Sophia A Vandewater, Loren H Parsons, Karen L Houseknecht, Tobin J Dickerson, Michael A Taffe
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44652 (2012)
The drug 4-methylmethcathinone (4-MMC; aka, mephedrone, MMCAT, "plant food", "bath salts") is a recent addition to the list of popular recreational psychomotor-stimulant compounds. Relatively little information about this drug is available in the sci
Externí odkaz:
https://doaj.org/article/9927667dd81e46318d098f6faeb9fdda
Autor:
Friedbert Weiss, Audra L. Stinchcomb, David G. Stouffer, Gustavo González-Cuevas, Dana C. Hammell, Tony M. Kerr, Stan Lee Banks, Rémi Martin-Fardon, Loren H. Parsons
Publikováno v:
Neuropsychopharmacology. 43:2036-2045
Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa, has received attention for therapeutic potential in treating neurologic and psychiatric disorders. Recently, CBD has also been explored for potential in treating drug addic
Autor:
Rémi Martin-Fardon, Matthew W. Buczynski, Loren H. Parsons, Marisa Roberto, Robert Lintz, Luis A. Natividad, Michael Q. Steinman, Ilham Polis, Sarah A. Laredo, Cristina Irimia
Publikováno v:
Addiction Biology. 23:1117-1129
Repeated cycles of alcohol [ethanol (EtOH)] intoxication and withdrawal dysregulate excitatory glutamatergic systems in the brain and induce neuroadaptations in the medial prefrontal cortex (mPFC) that contribute to cognitive dysfunction. The mPFC is
Autor:
Rémi Martin-Fardon, Loren H. Parsons, David G. Stouffer, Francisco Javier Pavón, Antonia Serrano, Nimish Sidhpura, Benjamin F. Cravatt, Fernando Rodríguez de Fonseca, Ilham Polis
Publikováno v:
Addiction Biology. 23:723-734
Nicotine exerts its rewarding effects by promoting an increase in dopamine (DA) release in the nucleus accumbens (NAc), and this process is influenced by the endocannabinoid system. Fatty acid amide hydrolase (FAAH) is the main enzyme responsible for
Publikováno v:
Addiction Biology. 23:676-688
The central amygdala (CeA) is involved in the processing of anxiety and stress and plays a role in ethanol consumption. Chronic ethanol recruits stress systems in the CeA, leading to aversive withdrawal symptoms. Although primarily GABAergic, CeA con