Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lorella M T Canzoniero"'
Autor:
Carlo Corona, Valerio Frazzini, Elena Silvestri, Rossano Lattanzio, Rossana La Sorda, Mauro Piantelli, Lorella M T Canzoniero, Domenico Ciavardelli, Enrico Rizzarelli, Stefano L Sensi
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17971 (2011)
BackgroundThe pathogenic road map leading to Alzheimer's disease (AD) is still not completely understood; however, a large body of studies in the last few years supports the idea that beside the classic hallmarks of the disease, namely the accumulati
Externí odkaz:
https://doaj.org/article/6876e911f0ea48ffb015201abbaffa04
Autor:
Rossana Sirabella, Valeria Valsecchi, Serenella Anzilotti, Ornella Cuomo, Antonio Vinciguerra, Pasquale Cepparulo, Paola Brancaccio, Natascia Guida, Nicolas Blondeau, Lorella M. T. Canzoniero, Cristina Franco, Salvatore Amoroso, Lucio Annunziato, Giuseppe Pignataro
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Amyotrophic lateral sclerosis (ALS) is one of the most threatening neurodegenerative disease since it causes muscular paralysis for the loss of Motor Neurons in the spinal cord, brainstem and motor cortex. Up until now, no effective pharmacological t
Externí odkaz:
https://doaj.org/article/6ebd4e2ad47e4257bc7f4c4263b4c7eb
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Fifty years ago, the seminal work by John Olney provided the first evidence of the neurotoxic properties of the excitatory neurotransmitter glutamate. A process hereafter termed excitotoxicity. Since then, glutamate-driven neuronal death has been lin
Publikováno v:
The European journal of neuroscience. 15(3)
The proteasome is involved in multiple cellular processes including control of the cell cycle, apoptosis and intracellular signalling; loss of proteasome function has been postulated to participate in the pathogenesis of triplet repeat diseases. We e