Výsledky vyhledávání - "Lorella Giuseppina Pasquinucci"

ChemInform Abstract: Synthesis of (+)-(1′R,2′S) and (1′S,2′R)-6,11-Dimethyl-1,2,3,4,5,6-hexahydro-3-[ [2′-(alkoxycarbonyl)-2′-phenylcyclopropyl]methyl] -2,6-methano-3-benzazocin-8-ol. Comparison of the Affinities for σ1 and Opioid Receptors with Those of

Autor: Lorella Giuseppina Pasquinucci, M. S. Pappalardo, Santi Spampinato, Orazio Prezzavento, G. Ronsisvalle, Lucia Carboni, F. Vittorio, Agostino Marrazzo

Publikováno v: ChemInform. 29

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f564af189aceb64d91486976dc8536e
https://doi.org/10.1002/chin.199809207

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Nonpeptide analogues of dynorphin A(1-8): design, synthesis, and pharmacological evaluation of kappa-selective agonists

Autor: R Di Toro, Barbara Falcucci, Orazio Prezzavento, Valeria Pittalà, Giuseppe Ronsisvalle, Agostino Marrazzo, Santi Spampinato, Lorella Giuseppina Pasquinucci

Publikováno v: Journal of medicinal chemistry. 43(16)

Two novel series of kappa opioid receptor agonist analogues of MPCB-GRRI and MPCB-RRI, hybrid ligands of MPCB ((-)-cis-N-(2-phenyl-2-carbomethoxy)cyclopropylmethyl-N-normetazocine ) and of the C-terminal fragments of dynorphin A(1-8), have been synth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e2b34e25123917d72174f8b092ae32
https://pubmed.ncbi.nlm.nih.gov/10956208

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Investigaciones actuales en ligandos de receptores opiáceos

Autor: Ronsisvalle, G., Prezzavento, O., Lorella Giuseppina Pasquinucci, Marrazzo, A., Vittorio, F., Pappalardo, M. S., Bousquet, E.

Publikováno v: Scopus-Elsevier

Relevant developments have been achieved in the last twenty years in the search for opioid agonists and antagonists with selectivity for each receptor subpopulation. Recently, new benzomorphan derivatives have been synthesized and compounds with subs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4bd53f0775ae5af54c2e100d55d03cb5
https://hdl.handle.net/10481/83672

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Non-peptide ligands for opioid receptors. Design of k-specific agonists

Autor: M. S. Pappalardo, S Ferri, F. Vittorio, G Fronza, Lorella Giuseppina Pasquinucci, E Pistacchio, Santi Spampinato, Giuseppe Ronsisvalle, Carlo Romagnoli

A series of phenyl carboxyl esters 5a-d derived from N-(cyclopropylmethyl)normetazocine was synthesized and evaluated for its selectivity at mu, kappa, and delta opioid receptors. Compound 5a, although 43 times less potent than the reference compound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de74cf05d9a91327aebaedcccb604431
https://hdl.handle.net/11380/585526

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Synthesis of substituted pyrimidines, pyrazole[3,4-d]pyrimidines and imidazo[4,5-d]pyrimidines and evaluation of their antifungal activity

Autor: Ronsisvalle, G., Pappalardo, M. S., Vittorio, F., Lorella Giuseppina Pasquinucci, Bousquet, E., Oliveri, S., Cammarata, E.

Publikováno v: Scopus-Elsevier

Some pyrimidines, pyrazolo[3,4-d]pyrimidines and imidazo[4,5-d]pyrimidines bearing the 5-nitro- and 5-aminothienyl-2-sulfide functionalities on the pyrimidine nucleus were synthesized and evaluated for their antifungal activity against several strain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2b2fa3a505ad6125be6558c42c8020ae
https://pubmed.ncbi.nlm.nih.gov/2775419

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