Zobrazeno 1 - 10
of 740
pro vyhledávání: '"Lorelei A Mucci"'
Autor:
Christopher M Heaphy, Corinne E Joshu, John R Barber, Christine Davis, Jiayun Lu, Reza Zarinshenas, Edward Giovannucci, Lorelei A Mucci, Meir J Stampfer, Misop Han, Angelo M De Marzo, Tamara L Lotan, Elizabeth A Platz, Alan K Meeker
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 5, Pp 481-491 (2022)
Abstract Current biomarkers are inadequate prognostic predictors in localized prostate cancer making treatment decision‐making challenging. Previously, we observed that the combination of more variable telomere length among prostate cancer cells an
Externí odkaz:
https://doaj.org/article/d83e9cf0b5244fd6a2439370f8fc6cb4
Autor:
Konrad H Stopsack, Svitlana Tyekucheva, Molin Wang, Travis A Gerke, J Bailey Vaselkiv, Kathryn L Penney, Philip W Kantoff, Stephen P Finn, Michelangelo Fiorentino, Massimo Loda, Tamara L Lotan, Giovanni Parmigiani, Lorelei A Mucci
Publikováno v:
eLife, Vol 10 (2021)
Tissue microarrays (TMAs) have been used in thousands of cancer biomarker studies. To what extent batch effects, measurement error in biomarker levels between slides, affects TMA-based studies has not been assessed systematically. We evaluated 20 pro
Externí odkaz:
https://doaj.org/article/5d3559e372204133ba3415106d7b03ea
Autor:
Daniela Börnigen, Svitlana Tyekucheva, Xiaodong Wang, Jennifer R Rider, Gwo-Shu Lee, Lorelei A Mucci, Christopher Sweeney, Curtis Huttenhower
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 4, p e1004820 (2016)
Molecular research in cancer is one of the largest areas of bioinformatic investigation, but it remains a challenge to understand biomolecular mechanisms in cancer-related pathways from high-throughput genomic data. This includes the Nuclear-factor-k
Externí odkaz:
https://doaj.org/article/fc364c0737e14252bdb83a84c8d7de02
Autor:
Johanna E Torfadottir, Unnur A Valdimarsdottir, Lorelei A Mucci, Julie L Kasperzyk, Katja Fall, Laufey Tryggvadottir, Thor Aspelund, Orn Olafsson, Tamara B Harris, Eirikur Jonsson, Hrafn Tulinius, Vilmundur Gudnason, Hans-Olov Adami, Meir Stampfer, Laufey Steingrimsdottir
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59799 (2013)
To examine whether fish and fish oil consumption across the lifespan is associated with a lower risk of prostate cancer.The study was nested among 2268 men aged 67-96 years in the AGES-Reykjavik cohort study. In 2002 to 2006, dietary habits were asse
Externí odkaz:
https://doaj.org/article/503cac72cfcd4164aaf99ab399cecfa7
Autor:
Fang Fang, Julie L Kasperzyk, Irene Shui, Whitney Hendrickson, Bruce W Hollis, Katja Fall, Jing Ma, J Michael Gaziano, Meir J Stampfer, Lorelei A Mucci, Edward Giovannucci
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18625 (2011)
Laboratory evidence suggests that vitamin D might influence prostate cancer prognosis.We examined the associations between prediagnostic plasma levels of 25(OH)vitamin D [25(OH)D] and 1,25(OH)(2) vitamin D [1,25(OH)(2)D] and mortality among 1822 part
Externí odkaz:
https://doaj.org/article/c9835b12271b424596916654e4dd14c8
Autor:
Mark M Pomerantz, Yashaswi Shrestha, Richard J Flavin, Meredith M Regan, Kathryn L Penney, Lorelei A Mucci, Meir J Stampfer, David J Hunter, Stephen J Chanock, Eric J Schafer, Jennifer A Chan, Josep Tabernero, José Baselga, Andrea L Richardson, Massimo Loda, William K Oh, Philip W Kantoff, William C Hahn, Matthew L Freedman
Publikováno v:
PLoS Genetics, Vol 6, Iss 11, p e1001204 (2010)
Genome-wide association studies (GWAS) have established a variant, rs10993994, on chromosome 10q11 as being associated with prostate cancer risk. Since the variant is located outside of a protein-coding region, the target genes driving tumorigenesis
Externí odkaz:
https://doaj.org/article/dc6fbfe2b95b4198812b5ad9f1ad0a44
Autor:
Katja Fall, Fang Fang, Lorelei A Mucci, Weimin Ye, Ove Andrén, Jan-Erik Johansson, Swen-Olof Andersson, Pär Sparén, Georg Klein, Meir Stampfer, Hans-Olov Adami, Unnur Valdimarsdóttir
Publikováno v:
PLoS Medicine, Vol 6, Iss 12, p e1000197 (2009)
BackgroundStressful life events have been shown to be associated with altered risk of various health consequences. The aim of the present study was to investigate whether the emotional stress evoked by a prostate cancer diagnosis increases the immedi
Externí odkaz:
https://doaj.org/article/d388d92266b141d895489f05c2923a7e
Autor:
Haojie Li, Meir J Stampfer, J Bruce W Hollis, Lorelei A Mucci, J Michael Gaziano, David Hunter, Edward L Giovannucci, Jing Ma
Publikováno v:
PLoS Medicine, Vol 4, Iss 3, p e103 (2007)
Vitamin D insufficiency is a common public health problem nationwide. Circulating 25-hydroxyvitamin D3 (25[OH]D), the most commonly used index of vitamin D status, is converted to the active hormone 1,25 dihydroxyvitamin D3 (1,25[OH]2D), which, opera
Externí odkaz:
https://doaj.org/article/06d05b864d4140e4ad39826554974dcc
Autor:
Chaoran Ma, Caroline Ericsson, Sigrid V. Carlsson, Hans Lilja, Adam Kibel, Rebecca E. Graff, Anna Plym, Edward Giovannucci, Lorelei A. Mucci, Mark A. Preston, Kathryn L. Penney
Publikováno v:
European Urology Open Science. 50:27-30
Autor:
Yiwen Zhang, Konrad H. Stopsack, Kana Wu, Mingyang Song, Lorelei A. Mucci, Edward Giovannucci
Publikováno v:
Journal of Urology. 209:549-556
Biological and experimental evidence support restoration of normal zinc levels in malignant prostate cells as a promising prostate cancer treatment, yet the influence of zinc supplementation after diagnosis on prostate cancer survival in a human popu