Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Loreen Stillwell"'
Autor:
Heidi R. Hope, Susan Hockerman, Matt Saabye, Loreen Stillwell, Rakesh Basavalingappa, Catherine Emanual, Steve Mnich, Madison Bangs, Emma Huff, Aparna Kaul, Anne Hildebrand, Marco Cardillo, Ajay Aggarwal, Joseph B. Monahan
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c62b558510ebdeea0073ddc1a1f8fda1
https://doi.org/10.1124/jpet.122.541040
https://doi.org/10.1124/jpet.122.541040
Autor:
Jeffrey L. Hirsch, Robert H. Keith, Loreen Stillwell, Pamela De Ciechi, Jian Zhang, Ravi G. Kurumbail, Richard M. Leimgruber, Shaun R. Selness, Huey S. Shieh, Stephen J. Mnich, Yan Zhang, Barry L. Burnette, Michael Hepperle, Robert P. Compton, Raj Devraj, Gail Jungbluth, Win Naing, Joseph B. Monahan, Joseph Portanova, Gary D. Anderson, Heidi R. Hope
Publikováno v:
Pharmacology. 84:42-60
SD0006 is a diarylpyrazole that was prepared as an inhibitor of p38 kinase-alpha (p38alpha). In vitro, SD0006 was selective for p38alpha kinase over 50 other kinases screened (including p38gamma and p38delta with modest selectivity over p38beta). Cry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417af8711e84292fd44a13daf8ddc013
https://doi.org/10.1159/000227286
https://doi.org/10.1159/000227286
Publikováno v:
Journal of the American Chemical Society. 120:11364-11373
Succinimido, amido, and ester functionalized tetrafluoroaryl azides selectively oxidize bisdiphenylphosphinomethane at one of the P(III) centers giving (iminophosphorano)phosphines 6, 7, and 8 respectively in high yields. Succinimido functionalized p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba7ec28307e6b75a4078adb19a68ece5
https://doi.org/10.1021/ja9802403
https://doi.org/10.1021/ja9802403
Autor:
Gabriel Mbalaviele, Rajesh V. Devraj, Elizabeth G. Webb, Jeffrey L. Hirsch, Heidi R. Hope, Matthew J. Saabye, Dean Messing, Jian Zhang, Joseph B. Monahan, Shaun R. Selness, John F. Schindler, Loreen Stillwell, Barry L. Burnette, Gary D. Anderson, Robert P. Compton, Xiong Li, Robert H. Keith
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 331(3)
Signal transduction through the p38 mitogen-activated protein (MAP) kinase pathway is central to the transcriptional and translational control of cytokine and inflammatory mediator production. p38 MAP kinase inhibition hence constitutes a promising t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bf14977f74059927334568730cf7b0
https://pubmed.ncbi.nlm.nih.gov/19720877
https://pubmed.ncbi.nlm.nih.gov/19720877