Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Loredana Moro"'
Autor:
Shanshan Duan, Loredana Moro, Rui Qu, Daniele Simoneschi, Hyunwoo Cho, Shaowen Jiang, Huiyong Zhao, Qing Chang, Elisa de Stanchina, Arnaldo A. Arbini, Michele Pagano
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109870- (2021)
Summary: FBXO31 is the substrate receptor of one of many CUL1-RING ubiquitin ligase (CRL1) complexes. Here, we show that low FBXO31 mRNA levels are associated with high pre-operative prostate-specific antigen (PSA) levels and Gleason grade in human p
Externí odkaz:
https://doaj.org/article/f42df1e8c44b4669aa236586fa582c8a
Autor:
Loredana Moro, Michele Pagano
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 6 (2020)
Epigenetic reprogramming is emerging as a key mechanism for metastasis development. Our study identified a novel regulatory mechanism whereby promoter methylation-mediated epigenetic silencing of the gene encoding the ubiquitin ligase subunit F-box/L
Externí odkaz:
https://doaj.org/article/4ed81b080d3e400fb793259568ebaa26
Autor:
Lara Gibellini, Loredana Moro
Publikováno v:
Cells, Vol 10, Iss 7, p 1765 (2021)
Programmed cell death is a conserved evolutionary process of cell suicide that is central to the development and integrity of eukaryotic organisms [...]
Externí odkaz:
https://doaj.org/article/2200bfdd21064eacae7a5e31130b78ee
Autor:
Roberta Romano, Anna Picca, Leonardo Henry Umberto Eusebi, Emanuele Marzetti, Riccardo Calvani, Loredana Moro, Cecilia Bucci, Flora Guerra
Publikováno v:
Cells, Vol 10, Iss 6, p 1361 (2021)
Pancreatic cancer (PC) is among the most devastating digestive tract cancers worldwide. This cancer is characterized by poor diagnostic detection, lack of therapy, and difficulty in predicting tumorigenesis progression. Although mutations of key onco
Externí odkaz:
https://doaj.org/article/99d5ac1581b24ee49d4611230c1c1979
Autor:
Loredana Moro
Publikováno v:
Biology, Vol 9, Iss 12, p 479 (2020)
Mitochondria are highly dynamic and regulated organelles implicated in a variety of important functions in the cell, including energy production, fatty acid metabolism, iron homeostasis, programmed cell death, and cell signaling. Changes in mitochond
Externí odkaz:
https://doaj.org/article/37904d5be9ae4df7adc8f89c7ed2e096
Autor:
Flora Guerra, Nicoletta Guaragnella, Arnaldo A. Arbini, Cecilia Bucci, Sergio Giannattasio, Loredana Moro
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Epithelial-to-mesenchymal transition (EMT) allows epithelial cancer cells to assume mesenchymal features, endowing them with enhanced motility and invasiveness, thus enabling cancer dissemination and metastatic spread. The induction of EMT is orchest
Externí odkaz:
https://doaj.org/article/482118d7c8f84de1bd6e1cb0be9bdeb0
Publikováno v:
Cellular Oncology, Vol 30, Iss 4, Pp 307-322 (2008)
Mitochondrial dysfunction resulting from mitochondrial DNA (mtDNA) mutations and/or depletion has been correlated with cancer progression and drug resistance. To investigate the role of mtDNA in prostate cancer progression, we used LNCaP and PC-3 pro
Externí odkaz:
https://doaj.org/article/5b0eda41d8aa4e1c944591ff22c9b080
Autor:
Ester Antelmi, Rosa A Cardone, Maria R Greco, Rosa Rubino, Francesca Di Sole, Nicola A Martino, Valeria Casavola, Marialuisa Carcangiu, Loredana Moro, Stephan J Reshkin
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75113 (2013)
Extracellular matrix (ECM) degradation is a critical process in tumor cell invasion and requires matrix degrading protrusions called invadopodia. The Na(+)/H(+) exchanger (NHE1) has recently been shown to be fundamental in the regulation of invadopod
Externí odkaz:
https://doaj.org/article/c46e7b35457241e68fc1e7d1944a891b
Autor:
Lucia R. Languino, Zhong Jiang, Chin-Lee Wu, Chung-Cheng Hsieh, Joanne E. Murphy-Ullrich, Loredana Moro, Hira Lal Goel
Supplementary Figure Legend from β1 Integrin Cytoplasmic Variants Differentially Regulate Expression of the Antiangiogenic Extracellular Matrix Protein Thrombospondin 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1467b96a1179fa2bfbdefea0effc0687
https://doi.org/10.1158/0008-5472.22377746
https://doi.org/10.1158/0008-5472.22377746
Autor:
Lucia R. Languino, Zhong Jiang, Chin-Lee Wu, Chung-Cheng Hsieh, Joanne E. Murphy-Ullrich, Loredana Moro, Hira Lal Goel
Supplementary Figure 1 from β1 Integrin Cytoplasmic Variants Differentially Regulate Expression of the Antiangiogenic Extracellular Matrix Protein Thrombospondin 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fb431ad36d37ca0c1aae0ae313773e
https://doi.org/10.1158/0008-5472.22377749.v1
https://doi.org/10.1158/0008-5472.22377749.v1