Single-cell RNA sequencing identifies a population of human liver-type ILC1s

Autor: Krämer, Benjamin, Nalin, Ansel P., Ma, Feiyang, Eickhoff, Sarah, Lutz, Philipp, Leonardelli, Sonia, Goeser, Felix, Finnemann, Claudia, Hack, Gudrun, Raabe, Jan, ToVinh, Michael, Ahmad, Sarah, Hoffmeister, Christoph, Kaiser, Kim M., Manekeller, Steffen, Branchi, Vittorio, Bald, Tobias, Hölzel, Michael, Hüneburg, Robert, Nischalke, Hans Dieter, Semaan, Alexander, Langhans, Bettina, Kaczmarek, Dominik J., Benner, Brooke, Lordo, Matthew R., Kowalski, Jesse, Gerhardt, Adam, Timm, Jörg, Toma, Marieta, Mohr, Raphael, Türler, Andreas, Charpentier, Arthur, van Bremen, Tobias, Feldmann, Georg, Sattler, Arne, Kotsch, Katja, Abdallah, Ali T., Strassburg, Christian P., Spengler, Ulrich, Carson, William E., III, Mundy-Bosse, Bethany L., Pellegrini, Matteo, O’Sullivan, Timothy E., Freud, Aharon G., Nattermann, Jacob

Publikováno v: In Cell Reports 31 January 2023 42(1)

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Type 3 Innate Lymphoid Cells Protect Leukemic Blasts from Natural Killer Cell Cytotoxicity in Acute Myeloid Leukemia

Autor: Lordo, Matthew R ^*, Dinh, Thanh T ^*, Shilo, Nikolas A ^*, Altynova, Ekaterina S ^*, Jeremy, Erin G. ^*, Varkey, Aditi ^*, Collins, Patrick L ^*, Freud, Aharon G, Mundy-Bosse, Bethany L

Publikováno v: In Blood 15 November 2022 140 Supplement 1:5494-5495

Identification and Targeting of the Developmental Blockade in Extranodal Natural Killer/T-cell Lymphoma.

Autor: Mundy-Bosse BL; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Weigel C; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Wu YZ; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Abdelbaky S; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Youssef Y; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio., Casas SB; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio., Polley N; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio., Ernst G; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Young KA; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., McConnell KK; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Nalin AP; Medical Scientist Training Program, The Ohio State University, Columbus, Ohio., Wu KG; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Broughton M; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Lordo MR; Medical Scientist Training Program, The Ohio State University, Columbus, Ohio., Altynova E; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Hegewisch-Solloa E; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York., Enriquez-Vera DY; Instituto Nacional de Enfermedades Neoplasticas, Lima, Peru., Dueñas D; Instituto Nacional de Enfermedades Neoplasticas, Lima, Peru., Barrionuevo C; Instituto Nacional de Enfermedades Neoplasticas, Lima, Peru., Yu SC; Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan., Saleem A; Department of Pathology, Stanford University School of Medicine, Stanford, California., Suarez CJ; Department of Pathology, Stanford University School of Medicine, Stanford, California., Briercheck EL; Department of Medicine, Division of Hematology and Medical Oncology, Fred Hutchinson Cancer Research Institute and the University of Washington, Seattle, Washington., Molina-Kirsch H; Laboratorio de Patologia, Guatemala City, Guatemala., Loughran TP; Division of Hematology, Department of Medicine, University of Virginia Cancer Center, Charlottesville, Virginia., Weichenhan D; Division of Epigenomics, The German Cancer Research Center (DKFZ), Heidelberg, Germany., Plass C; Division of Epigenomics, The German Cancer Research Center (DKFZ), Heidelberg, Germany., Reneau JC; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Mace EM; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York., Gamboa FV; Department of Medical Oncology, Liga Nacional Contra el Cáncer, Guatemala City, Guatemala., Weinstock DM; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Natkunam Y; Department of Pathology, Stanford University School of Medicine, Stanford, California., Caligiuri MA; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Los Angeles, California., Mishra A; Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania., Porcu P; Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania., Baiocchi RA; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Brammer JE; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio., Freud AG; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio.; Department of Pathology, The Ohio State University, Columbus, Ohio., Oakes CC; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio.; The Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio.; Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio.

Publikováno v: Blood cancer discovery [Blood Cancer Discov] 2022 Mar 01; Vol. 3 (2), pp. 154-169.