Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Loralee McMahon"'
Autor:
David G. Hicks, Brandon Buscaglia, Hideki Goda, Loralee McMahon, Takako Natori, Bradley Turner, Armen Soukiazian, Hisatake Okada, Yasushi Nakano
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Clinical assays for the assessment of the human epidermal growth factor receptor-2 (HER2) status in breast cancer include immunohistochemistry (IHC) and in situ hybridization (ISH), both of which have limitations. Recent studies h
Externí odkaz:
https://doaj.org/article/ec5b832d0cd84a998c791ad3185c8cd5
Autor:
Guang-Qian Xiao, Pamela Unger, Qi Yang, Yayoi Kinoshita, Kyra Singh, Loralee McMahon, Kent Nastiuk, Kai Sha, John Krolewski, David Burstein
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121318 (2015)
PLZF is a transcription repressor, which plays a critical role in development, spermatogenesis and oncogenesis. Down-regulation of PLZF has been found in various tumor cell lines. There has been virtually no tissue study on the expression of PLZF in
Externí odkaz:
https://doaj.org/article/31f6bac41e4648e9b5818f06acc69fba
Publikováno v:
American Journal of Clinical Pathology. 154:761-766
ObjectivesAutoimmune metaplastic atrophic gastritis (AMAG) is an underrecognized entity, especially in its early stage. This study assessed whether the use of gastrin immunohistochemistry would increase sensitivity for diagnosing early AMAG.MethodsTh
Autor:
Brooke R Koltz, Christa L. Whitney-Miller, David G. Hicks, Jill Henry, Loralee McMahon, Brandon Buscaglia, James Guo, Aaron R Huber
Publikováno v:
American Journal of Clinical Pathology. 151:461-468
OBJECTIVES Human epidermal growth factor receptor 2 (HER2) is expressed in some gastric and gastroesophageal junction adenocarcinomas. There were two goals: assess the impact of specimen type on HER2 status and evaluate HER2 concordance with multiple
Autor:
Brandon Buscaglia, Bradley M. Turner, Yasushi Nakano, Hideki Goda, David G. Hicks, Takako Natori, Armen Soukiazian, Loralee McMahon, Hisatake Okada
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
BMC Cancer
BMC Cancer
Background Clinical assays for the assessment of the human epidermal growth factor receptor-2 (HER2) status in breast cancer include immunohistochemistry (IHC) and in situ hybridization (ISH), both of which have limitations. Recent studies have sugge
Autor:
Jennifer J. Findeis-Hosey, Raul S. Gonzalez, Diana Agostini-Vulaj, Loralee McMahon, Christa L. Whitney-Miller
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 26:288-293
Insulin-like growth factor-II messenger RNA-binding protein-3 (IMP3), is an oncofetal protein whose aberrant expression has previously been detected in multiple malignant neoplasms. Pulmonary neuroendocrine carcinomas demonstrate increased expression
Autor:
Bradley M. Turner, T Natori, Siraj M. Ali, Hideki Goda, Jeff Sperinde, Kim Leitzel, Y Nakano, Monali Vasekar, Jill Henry, Hisatake Okada, Brandon Buscaglia, Marcus D’Aguiar, Loralee McMahon, Wei Huang, David G. Hicks, A. Lipton
Publikováno v:
Cancer Research. 79:P1-03
Background: In 2013, the ASCO/CAP consensus panel published updated guidelines for HER2 testing in breast cancer that modified the definition of HER2 amplification by in situ hybridization (ISH), creating five new prognostic categories (group 1: clas
Publikováno v:
American Journal of Clinical Pathology. 148:477-484
Objectives To determine whether histologic features could help identify gastric carcinomas with lymphoid stroma associated with microsatellite instability (MSI) (ie, "medullary carcinomas"), Epstein-Barr virus (EBV) infection (termed lymphoepitheliom
Autor:
Leila Russo, David G. Hicks, Loralee McMahon, Mary Falzon, Kirsten D. Hoff, Patrizia Dell'Orto, Yaron Y. Levy, Keith W. Miller, Giuseppe Viale
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology
Supplemental Digital Content is available in the text.
The analysis of estrogen receptor (ER) and progesterone receptor (PR) expression levels by immunohistochemistry is an important part of the initial evaluation of breast cancer and critically
The analysis of estrogen receptor (ER) and progesterone receptor (PR) expression levels by immunohistochemistry is an important part of the initial evaluation of breast cancer and critically
Publikováno v:
Human Pathology. 56:16-21
The Cancer Genome Atlas Research Network recently classified gastric adenocarcinoma into 4 molecular subtypes: Epstein-Barr virus-positive tumors, microsatellite-unstable tumors, tumors with chromosomal instability, and genomically stable tumors. We