Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Loraine L.Y. Chiu"'
Autor:
Cristóbal López-Jiménez, Loraine L.Y. Chiu, Stephen D. Waldman, Farshid Guilak, Thomas G. Koch
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 2, Pp 100263- (2022)
Objective: To evaluate the effect of Transient Receptor Potential Vanilloid 4 (TRPV4) cation channel modulation on mesenchymal stromal cell (MSC)-derived neocartilage. Methods: RT-PCR was performed to evaluate mRNA levels of chondrogenic, hypertrophi
Externí odkaz:
https://doaj.org/article/cad3083abb58407aa0f7b6cb6e187aec
Autor:
Cristóbal López-Jiménez, Sarah I.M. Lepage, Loraine L.Y. Chiu, Stephen D. Waldman, Matthew K. Vickaryous, Rita A. Kandel, Thomas G. Koch
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 2, Iss 1, Pp 100036- (2022)
Background: In vitro tissue engineering of osteochondral implants is an attractive solution to circumvent the limitations of these therapies by providing readily available grafts for patients. Objective: Generate and evaluate the mechanical propertie
Externí odkaz:
https://doaj.org/article/3b488b79510e4ef396b2475d72264f60
Autor:
Roberto Tarantino, Stephen C. Pang, Joanna F. Weber, Man Yat Tse, Stephen D. Waldman, Loraine L.Y. Chiu, Davide D. Bardana
Publikováno v:
Biotechnology and Bioengineering. 118:4119-4128
A major shortcoming in cartilage tissue engineering is the low biosynthetic response of chondrocytes. While different strategies have been investigated, a novel approach may be to control nutrient metabolism. Although known for their anaerobic metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96dc6c3efce7812a01e6110d6e591a6f
https://doi.org/10.1002/bit.27888
https://doi.org/10.1002/bit.27888
Autor:
Cristóbal López-Jiménez, Loraine L.Y. Chiu, Stephen D. Waldman, Farshid Guilak, Thomas G. Koch
Publikováno v:
Osteoarthritis and cartilage open. 4(2)
To evaluate the effect of Transient Receptor Potential Vanilloid 4 (TRPV4) cation channel modulation on mesenchymal stromal cell (MSC)-derived neocartilage.RT-PCR was performed to evaluate mRNA levels of chondrogenic, hypertrophic and candidate mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f6584344854a87c6c10b9af03393de
https://pubmed.ncbi.nlm.nih.gov/36475280
https://pubmed.ncbi.nlm.nih.gov/36475280
Autor:
Mitchell Lee, S. Sadanand, Loraine L.Y. Chiu, Dafna Sussman, Eunyoung Cho, Stephen D. Waldman, Doshina Naila
Publikováno v:
Polymers, Vol 13, Iss 1831, p 1831 (2021)
Polymers
Volume 13
Issue 11
Polymers
Volume 13
Issue 11
Silicone rubber's silicone-oxygen backbones give unique material properties which are applicable in various biomedical devices. Due to the diversity of potential silicone rubber compositions, the material properties can vary widely. This paper charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b70e50e97e07acda2a5f05296a32d07
https://www.mdpi.com/2073-4360/13/11/1831
https://www.mdpi.com/2073-4360/13/11/1831
Publikováno v:
Cartilage
Objective Although tissue engineering is a promising option for articular cartilage repair, it has been challenging to generate functional cartilaginous tissue. While the synthetic response of chondrocytes can be influenced by various means, most app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6333b21f58cf77b9fbc5fbc41ec8c332
https://doi.org/10.1177/1947603519841677
https://doi.org/10.1177/1947603519841677
Autor:
Loraine L.Y. Chiu, Stephen D. Waldman, Yat Tse, Davide D. Bardana, Joanna F. Weber, Stephen C. Pang, Roberto Tarantino
Despite the potential of tissue engineering approaches for cartilage repair, a major shortcoming is the low biosynthetic response of chondrocytes. While different strategies have been investigated to upregulate tissue formation, a novel approach may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0791eba5aeee2a8172a09e79e7783193
https://doi.org/10.22541/au.161140633.32132152/v1
https://doi.org/10.22541/au.161140633.32132152/v1
Autor:
Malvika Nagrath, Loraine L.Y. Chiu, Alireza Rahimnejad Yazdi, Saidur Rahman, Stephen D. Waldman, Mark R. Towler, Andrew Mendonca, Heyu Ni, Reid C. Gallant
Publikováno v:
Journal of biomaterials applications. 35(8)
This study evaluates the hemostatic properties of tantalum-containing mesoporous bioactive glasses (Ta-MBGs) through a suite of in-vitro methods: hemolysis percentage, zeta potential, blood coagulation assays (Activated Partial Thromboplastin Time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a2f3cb323cfd3aae502a57360ec25f
https://pubmed.ncbi.nlm.nih.gov/33135948
https://pubmed.ncbi.nlm.nih.gov/33135948
Publikováno v:
Annals of Biomedical Engineering. 47:243-256
Dynamic mechanical stimulation has been an effective method to improve the growth of tissue engineering cartilage constructs derived from immature cells. However, when more mature cell populations are used, results are often variable due to the diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0089e0d5b7e191296b17e31ee31bc6
https://doi.org/10.1007/s10439-018-02123-x
https://doi.org/10.1007/s10439-018-02123-x
Autor:
Romina Shafaghi, Stephen D. Waldman, Emil H. Schemitsch, Mark R. Towler, Paul Zalzal, Anthony W. Wren, Marcello Papini, Loraine L.Y. Chiu, Omar Rodriguez
Publikováno v:
Bone and Joint Institute
© 2020 Wiley Periodicals, LLC. Titanium-containing borate bioactive glass scaffolds (0, 5, 15, and 20 mol %, identified as BRT0, BRT1, BRT3, and BRT4) with a microstructure similar to that of human trabecular bone were prepared and evaluated in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4f147bafb43f5bba628ebd339d69f1
https://pubmed.ncbi.nlm.nih.gov/32441417
https://pubmed.ncbi.nlm.nih.gov/32441417