Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lora Eshkar-Sebban"'
Autor:
Nathalie Assayag-Asherie, Dror Sever, Marika Bogdani, Pamela Johnson, Talya Weiss, Ariel Ginzberg, Sharon Perles, Lola Weiss, Lora Eshkar Sebban, Eva A Turley, Elimelech Okon, Itamar Raz, David Naor
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143589 (2015)
CD44 is a multi-functional receptor with multiple of isoforms engaged in modulation of cell trafficking and transmission of apoptotic signals. We have previously shown that injection of anti-CD44 antibody into NOD mice induced resistance to type 1 di
Externí odkaz:
https://doaj.org/article/b6d332add7894c959a5a9f27c825fff1
Autor:
Eli Okon, Mary K. Cowman, Shulamit B. Wallach-Dayan, Jorge Alemany, David Naor, Darja Kanduc, Xiayun Huang, Lora Eshkar-Sebban, Keren Or Amar, Libat Bar Lev, Maayan Hemed-Shaked, Sharona Elgavish, Jordi Armengol, Michal Melamed, Shaul Beyth, Jin Ryoun Kim, Haim Ovadia, Eli Kedar, Shmuel Cohen, Edward Chau
Publikováno v:
Journal of Autoimmunity. 124:102713
Despite the existence of potent anti-inflammatory biological drugs e.g., anti-TNF and anti IL-6 receptor antibodies, for treating chronic inflammatory and autoimmune diseases, these are costly and not specific. Cheaper oral available drugs remain an
Autor:
David Naor, Lola Weiss, Itamar Raz, Talya Weiss, Dror Sever, Ariel Ginzberg, Sharon Perles, Elimelech Okon, Nathalie Assayag-Asherie, Pamela Y. Johnson, Lora Eshkar Sebban, Marika Bogdani, Eva A. Turley
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0143589 (2015)
PLoS ONE, Vol 10, Iss 12, p e0143589 (2015)
CD44 is a multi-functional receptor with multiple of isoforms engaged in modulation of cell trafficking and transmission of apoptotic signals. We have previously shown that injection of anti-CD44 antibody into NOD mice induced resistance to type 1 di
Autor:
Nir Rosenblum, Avichai Shimoni, Simon D. Lytton, Ronit Yerushalmi, Efrat Refaeli, Arnon Nagler, Anfisa Stanevsky, Lora Eshkar-Sebban, David Naor, Yechiel N. Gellman, Orly Shimony, Reuven Or
Publikováno v:
Journal of Clinical Immunology. 32:173-188
We show here that the anti-T lymphocyte immunoglobulin (ATG) can induce Treg cells following 24-h incubation in human peripheral blood mononuclear cells (PBMCs). The ATG-induced Treg cells express known cell surface markers (e.g., CD25, FoxP3) and su
Autor:
Yechiel N. Gellman, David Naor, George J. Kahaly, Simon D. Lytton, Nir Rosenblum, Efrat Refaeli, Sameer Kassem, Orly Shimony, Jacob Ilany, Lora Eshkar-Sebban
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 96:422-429
Graves' orbitopathy (GO) is characterized by orbital T cell infiltration and local release of proinflammatory cytokines. We aimed to evaluate the involvement of baseline regulatory T (Treg) cells and rabbit anti-T lymphocyte globulin (rATG)-induced T
Autor:
David Naor, Alan Rubinow, Suhail Aamar, Itshak Golan, Ori Elkayam, Shlomo Nedvetzki, Ira Golan, Lora Eshkar-Sebban, Dan Caspi, Howard Amital, David Levartovsky
Publikováno v:
Journal of Autoimmunity. 28:99-113
Selective targeting of cells engaged in pathological activities is a major challenge for medical research. We generated monoclonal antibodies (mAbs) that exclusively bind, at concentrations ranging from 2 to 100 microg/ml, to a modified CD44 variant
Autor:
Eva A. Turley, Dan Caspi, Itshak Golan, Tali Garin, Lora Eshkar Sebban, Shlomo Nedvetzki, Shimon Slavin, David Naor, Lola Weiss, Marita Walmsley, Avner Yayon, Nathalie Assayag-Asherie, Ira Golan, Itamar Raz, Dimitrios Karussis, Yehiel Zick
Publikováno v:
Annals of the New York Academy of Sciences. 1110
CD44 is a multistructural and multifunctional glycoprotein, the diversity of which is generated by alternative splicing. In this communication we review some aspects related to CD44 structure and function in experimental autoimmune inflammation, focu
Autor:
Ira Golan, Alan Rubinow, Yehiel Zick, David Naor, Denise Ronen, David Levartovsky, Suhail Aamar, Lora Eshkar Sebban, Itshak Golan, Howard Amital, Ori Elkayam, Dan Caspi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 179(2)
The synovial fluid (SF) cells of rheumatoid arthritis (RA) patients express a specific CD44 variant designated CD44vRA. Using a cellular model of this autoimmune disease, we show in this study that the mammalian lectin, galectin-8 (gal-8), is a novel