Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Lora E. Rikans"'
Autor:
Lora E. Rikans
Publikováno v:
Nutritional Aspects of Aging ISBN: 9781351075145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0eb006eb74c8189b9238da8b3c4af6b
https://doi.org/10.1201/9781351075145-1
https://doi.org/10.1201/9781351075145-1
Autor:
Tetsuo Yamano, Lora E. Rikans
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 14:110-117
The mechanism of cadmium-mediated acute hepatotoxicity has been the subject of numerous investigations and although some uncertainties persist, sufficient evidence has emerged to provide a reasonable account of the toxic process. Acute hepatotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3b53637317408345e43b331159aa67
https://doi.org/10.1002/(sici)1099-0461(2000)14:2<110::aid-jbt7>3.0.co
https://doi.org/10.1002/(sici)1099-0461(2000)14:2<110::aid-jbt7>3.0.co
Autor:
K.Roger Hornbrook, Lora E. Rikans
Publikováno v:
Environmental Toxicology and Pharmacology. 4:339-344
Limited information is available regarding age-associated events that lead to differences in vulnerability to chemicals that injure the liver. For some agents, such as allyl alcohol, alterations in metabolic activation, by liver biotransformation enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f113b75f1dea12384995c3403c0822c7
https://doi.org/10.1016/s1382-6689(97)10032-1
https://doi.org/10.1016/s1382-6689(97)10032-1
Publikováno v:
Mechanisms of Ageing and Development. 91:165-169
Ascorbic acid content decreased with age in livers of male rats but not in those of female rats. The influence of aging on the regeneration of ascorbic acid from dehydroascorbic acid was investigated as a possible cause of declining ascorbate concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79810f04573ec0ff3e74da3b447ec297
https://doi.org/10.1016/s0047-6374(96)01784-8
https://doi.org/10.1016/s0047-6374(96)01784-8
Publikováno v:
Toxicology Letters. 81:159-165
Allyl alcohol-induced LDH leakage from isolated rat hepatocytes was preceded by a decrease in rhodamine 123 retention, signifying a loss of mitochondrial membrane potential. Addition of dithiothreitol (DTT) prevented the drop in membrane potential an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00648912b03331d3cbd30e6edcd66be
https://doi.org/10.1016/0378-4274(95)03426-9
https://doi.org/10.1016/0378-4274(95)03426-9
Publikováno v:
Mechanisms of Ageing and Development. 76:89-99
Severity of liver damage 24 h after intraperitoneal administration of carbon tetrachloride (0.2 ml/kg) was evaluated in female Fischer 344 rats aged 5, 14 and 28 months, i.e. in young adulthood, middle age and old age. Carbon tetrachloride-induced he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c172662883a184cb22743406d2b2d81
https://doi.org/10.1016/0047-6374(94)91584-9
https://doi.org/10.1016/0047-6374(94)91584-9
Publikováno v:
Experimental and Molecular Pathology. 59:27-37
The ability of concurrent intraperitoneal injections of endotoxin (0.1 micrograms/kg) and galactosamine (700 mg/kg) to produce liver damage was determined in fasted C57Bl/6 mice of different ages: 2 months (young), 6 months (mature), and 24 months (a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9065597be4f0bd8df038fb573fdfb1
https://doi.org/10.1006/exmp.1993.1024
https://doi.org/10.1006/exmp.1993.1024
Publikováno v:
Drug Development Research. 26:461-465
The purpose of this study was to investigate the influence of aging on the diurnal varitaion in glutathione (GSH) content of mouse liver. Young (7 months) and old (27 months) C57BL mice were housed under standarized conditions with lighting from 0800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c066bffc1abe2ff9ab733c592496445
https://doi.org/10.1002/ddr.430260409
https://doi.org/10.1002/ddr.430260409
Publikováno v:
Gerontology. 36:185-192
Rates of ethanol metabolism by alcohol dehydrogenase, the microsomal ethanol oxidizing system (MEOS), and catalase were similar in liver preparations from young (4-5 months) and old (24-27 months) female Fischer 344 rats. On the other hand, rates of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbcf29a63896d62be8d785a91dc957f
https://doi.org/10.1159/000213198
https://doi.org/10.1159/000213198
Autor:
Lora E. Rikans
Publikováno v:
Experimental Gerontology. 29:593-595
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77af3fe65ae4eb381ace9810ea0994b6
https://doi.org/10.1016/0531-5565(94)90042-6
https://doi.org/10.1016/0531-5565(94)90042-6