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pro vyhledávání: '"Lora A. Shiflett"'
Autor:
Lora A. Shiflett, LeAnn M. Tiede-Lewis, Yixia Xie, Yongbo Lu, Eleanor C. Ray, Sarah L. Dallas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Bone formation, remodeling and repair are dynamic processes, involving cell migration, ECM assembly, osteocyte embedding, and bone resorption. Using live-cell imaging, we previously showed that osteoblast assembly of the ECM proteins fibronectin and
Externí odkaz:
https://doaj.org/article/e3593e815eee4f6291791fa2b2a0fafb
Autor:
Sarah L. Dallas, Michael J. Wacker, Leticia Brotto, Kun Wang, Lora A. Shiflett, Lynda F. Bonewald, Jian Huang, Marco Brotto
Publikováno v:
Cell Cycle
Osteoporosis and sarcopenia (osteosarcopenia (OS)) are twin-aging diseases. The biochemical crosstalk between muscle and bone seems to play a role in OS. We have previously shown that osteocytes produce soluble factors with beneficial effects on musc
Autor:
Yixia Xie, Yongbo Lu, Sarah L. Dallas, Eleanor C. Ray, LeAnn M. Tiede-Lewis, Lora A. Shiflett
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Bone formation, remodeling and repair are dynamic processes, involving cell migration, ECM assembly, osteocyte embedding, and bone resorption. Using live-cell imaging, we previously showed that osteoblast assembly of the ECM proteins fibronectin and
Autor:
Moses V. Chao, Angus C. Wilson, Lora A. Shiflett, Hui-Lan Hu, Tony T. Huang, Ian Mohr, Mariko Kobayashi
SUMMARYThe mTOR pathway integrates both extracellular and intracellular signals and serves as a central regulator of cell metabolism, growth, survival and stress responses. Neurotropic viruses, such as herpes simplex virus-1 (HSV-1), also rely on cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d41524881cdef0e70dafaa9a09355c0
Autor:
Angus C. Wilson, Moses V. Chao, Hui-Lan Hu, Ian Mohr, Mariko Kobayashi, Lora A. Shiflett, Tony T. Huang
Publikováno v:
Mol Cell
The mTOR pathway integrates both extracellular and intracellular signals and serves as a central regulator of cell metabolism, growth, survival, and stress responses. Neurotropic viruses, such as herpes simplex virus-1 (HSV-1), also rely on cellular
Publikováno v:
Current osteoporosis reportsPapers of particular interest, published recently, have been highlighted as: •• Of major Importance. 16(4)
a). PURPOSE: Transgenic Cre lines are a valuable tool for conditionally inactivating or activating genes to understand their function. Here we provide an overview of Cre transgenic models used for studying gene function in bone cells and discuss thei
Global Reprogramming of the Cellular Translational Landscape Facilitates Cytomegalovirus Replication
Autor:
Caleb McKinney, Lora A. Shiflett, Christopher Bianco, Stuart M. Brown, Ian Mohr, Jiri Zavadil
Publikováno v:
Cell Reports, Vol 6, Iss 1, Pp 9-17 (2014)
Cell Reports, Vol 6, Iss 6, p 1175 (2014)
Cell Reports, Vol 6, Iss 6, p 1175 (2014)
SummaryUnlike many viruses that suppress cellular protein synthesis, host mRNA translation and polyribosome formation are stimulated by human cytomegalovirus (HCMV). How HCMV impacts the translationally regulated cellular mRNA repertoire and its cont
Autor:
Lora A. Shiflett, G S Read
Publikováno v:
Journal of Virology. 87:94-109
During lytic infections, the herpes simplex virus (HSV) virion host shutoff (Vhs) endoribonuclease degrades many host and viral mRNAs. Within infected cells it cuts mRNAs at preferred sites, including some in regions of translation initiation. Vhs bi
Publikováno v:
Journal of Virology. 82:6600-6609
The herpes simplex virus (HSV) virion host shutoff (Vhs) protein is an endoribonuclease that accelerates decay of many host and viral mRNAs. Purified Vhs does not distinguish mRNAs from nonmessenger RNAs and cuts target RNAs at many sites, yet within
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781493904273
Methods in Molecular Biology ISBN: 9781493904273
We describe a primary neuronal culture system suitable for molecular characterization of herpes simplex virus type 1 (HSV-1) infection, latency, and reactivation. While several alternative models are available, including infections of live animal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09aa4412c2cc9138b5f5dafe80ffeb90
https://europepmc.org/articles/PMC9161729/
https://europepmc.org/articles/PMC9161729/