A genetic variant in NRP1 is associated with worse response to ranibizumab treatment in neovascular AMD

Autor: Lorés de Motta, L, van Asten, F, Muether, P, Smailhodzic, D, Chen, JC, Koenekoop, RK, Fauser, S, Hoyng, C, den Hollander, A, de Jong, E

Publikováno v: VI. International Symposium on AMD-Age-Related Macular Degeneration-Emerging Concepts-Exploring known and Identifying new Pathways; 20150911-20150912; Baden-Baden; DOC15amd41 /20151001/

Purpose: The highly variable response to anti-vascular endothelial growth factor (VEGF) drugs in neovascular age-related macular degeneration (nvAMD) patients is, in part, due to genetic predisposition. Several studies have implicated genetic variabi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf2c406dce727f541580c95abed2575

Genetic and environmental risk factors for extramacular drusen.

Autor: Altay L; Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany., Subiras X; Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany.; Cologne Image Reading Center, Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany., Lorés de Motta L; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands.; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands., Schick T; Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany.; Cologne Image Reading Center, Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany.; AugenZentrum Siegburg, MVZ ADTC Siegburg GmbH, Siegburg, Germany., Berghold A; Cologne Image Reading Center, Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany., Hoyng CB; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands., den Hollander AI; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands.; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, the Netherlands., Fauser S; Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany., Sadda SR; Doheny Eye Institute, UCLA, Los Angeles, CA., Liakopoulos S; Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany.; Cologne Image Reading Center, Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne, Germany.

Publikováno v: Molecular vision [Mol Vis] 2020 Oct 04; Vol. 26, pp. 661-669. Date of Electronic Publication: 2020 Oct 04 (Print Publication: 2020).