Higher Striatal Dopamine is Related With Lower Physical Performance Fatigability in Community-Dwelling Older Adults.

Autor: Rosano C; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Chahine LM; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Gay EL; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Coen PM; AdventHealth Research Institute, Orlando, Florida, USA., Bohnen NI; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA., Studenski SA; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., LoPresti B; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Rosso AL; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Huppert T; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Newman AB; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Royse SK; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Kritchevsky SB; Gerontology and Geriatric Medicine, Wake Forest University, Winston-Salem, North Carolina, USA., Glynn NW; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Publikováno v: The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2024 Nov 01; Vol. 79 (11).

Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model.

Autor: Leuzy A; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.; Critical Path for Alzheimer's Disease (CPAD) Consortium, Critical Path Institute, Tucson, Arizona, USA.; Enigma Biomedical Group, Knoxville, Tennessee, USA., Raket LL; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.; Eli Lilly and Company, Indianapolis, Indiana, USA., Villemagne VL; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Florey Department of Neuroscience, University of Melbourne, Parkville, Victoria, Australia.; Department of Molecular Imaging & Therapy, Austin Health, Heidelberg, Victoria, Australia., Klein G; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Tonietto M; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Olafson E; Clinical Imaging Group, Genentech, Inc., South San Francisco, California, USA., Baker S; Lawrence Berkeley National Laboratory, Berkeley, California, USA., Saad ZS; Janssen Research & Development, Merryfield Row San Diego, California, USA., Bullich S; Life Molecular Imaging GmbH, Berlin, Germany., Lopresti B; Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Bohorquez SS; Clinical Imaging Group, Genentech, Inc., South San Francisco, California, USA., Boada M; Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Av. de Monforte de Lemos, Madrid, Spain., Betthauser TJ; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.; Department of Medicine Division of Geriatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.; Department of Medical Physics, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA., Charil A; Eisai, Inc., Nutley, New Jersey, USA., Collins EC; Eli Lilly and Company, Indianapolis, Indiana, USA., Collins JA; Biogen, Cambridge, Massachusetts, USA., Cullen N; Critical Path for Alzheimer's Disease (CPAD) Consortium, Critical Path Institute, Tucson, Arizona, USA., Gunn RN; Invicro, Hammersmith Hospital, London, UK.; Brain Sciences, Imperial College London, Hammersmith Hospital, London, UK., Higuchi M; Department of Functional Brain Imaging, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Inage-ku, Chiba-shi, Chiba, Japan., Hostetler E; Merck & Co., Inc, West Point, Pennsylvania, USA., Hutchison RM; Biogen, Cambridge, Massachusetts, USA., Iaccarino L; Eli Lilly and Company, Indianapolis, Indiana, USA., Insel PS; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA., Irizarry MC; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA., Jack CR Jr; Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA., Jagust WJ; University of California Berkeley, Lawrence Berkeley National Laboratory, Berkeley, California, USA., Johnson KA; Harvard Medical School, Department of Radiology, Boston, Minnesota, USA.; Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, Minnesota, USA., Johnson SC; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.; Department of Medicine Division of Geriatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.; Department of Medical Physics, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA., Karten Y; Critical Path for Alzheimer's Disease (CPAD) Consortium, Critical Path Institute, Tucson, Arizona, USA., Marquié M; Department of Medicine Division of Geriatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.; Department of Medical Physics, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, USA., Mathotaarachchi S; Enigma Biomedical Group, Knoxville, Tennessee, USA., Mintun MA; Eli Lilly and Company, Indianapolis, Indiana, USA., Ossenkoppele R; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.; Amsterdam University Medical Center, Neuroscience Campus Amsterdam, Alzheimercenter, HZ Amsterdam, the Netherlands., Pappas I; Department of Psychology, Helen Wills Neuroscience Institute, University of California, Berkeley, California, USA.; Department of Neurology, VA Northern California Health Care System, Martinez, California, USA., Petersen RC; Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA., Rabinovici GD; Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, California, USA.; Department of Radiology & Biomedical Imaging, University of California, San Francisco, California, USA., Rosa-Neto P; Translational Neuroimaging Laboratory, Department of Neurology and Neurosurgery, Faculty of Medicine, The McGill University Research Centre for Studies in Aging, McGill University, Verdun, Quebec, Canada.; Montreal Neurological Institute, McGill University, Montréal, Québec, Canada., Schwarz CG; Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA., Smith R; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund, Sweden., Stephens AW; Life Molecular Imaging GmbH, Berlin, Germany., Whittington A; Invicro, Hammersmith Hospital, London, UK., Carrillo MC; Alzheimer's Association, Chicago, Illinois, USA., Pontecorvo MJ; Eli Lilly and Company, Indianapolis, Indiana, USA., Haeberlein SB; Enigma Biomedical Group, Knoxville, Tennessee, USA., Dunn B; Senior advisor to CPAD Consortium, Critical Path Institute, Tucson, Arizona, USA., Kolb HC; Enigma Biomedical Group, Knoxville, Tennessee, USA., Sivakumaran S; Critical Path for Alzheimer's Disease (CPAD) Consortium, Critical Path Institute, Tucson, Arizona, USA., Rowe CC; Florey Department of Neuroscience, University of Melbourne, Parkville, Victoria, Australia.; Department of Molecular Imaging & Therapy, Austin Health, Heidelberg, Victoria, Australia.; The Australian Dementia Network (ADNeT), The University of Melbourne, Parkville, Victoria, Australia., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Doré V; Department of Molecular Imaging & Therapy, Austin Health, Heidelberg, Victoria, Australia.; Health and Biosecurity Flagship, The Australian eHealth Research Centre, CSIRO, Parkville, Victoria, Australia.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Sep; Vol. 20 (9), pp. 5833-5848. Date of Electronic Publication: 2024 Jul 23.

Sex-dependent alterations in hippocampal connectivity are linked to cerebrovascular and amyloid pathologies in normal aging.

Autor: Schweitzer N; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Li J; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Thurston RC; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Lopresti B; Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Klunk WE; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Snitz B; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Tudorascu D; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Cohen A; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Kamboh MI; Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Halligan-Eddy E; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Iordanova B; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Villemagne VL; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Aizenstein H; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Wu M; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Feb; Vol. 20 (2), pp. 914-924. Date of Electronic Publication: 2023 Oct 11.

CenTauR: Toward a universal scale and masks for standardizing tau imaging studies.

Autor: Villemagne VL; Department of Psychiatry University of Pittsburgh Pittsburgh Pennsylvania USA.; Department of Molecular Imaging & Therapy Austin Health Melbourne Victoria Australia., Leuzy A; Clinical Memory Research Unit Department of Clinical Sciences Lund University Malmö Sweden., Bohorquez SS; Genentech Inc. South San Francisco California USA., Bullich S; Life Molecular Imaging GmbH Berlin Germany., Shimada H; Department of Functional Brain Imaging National Institutes for Quantum and Radiological Science and Technology Chiba Japan.; Brain Research Institute Niigata University Niigata Japan., Rowe CC; Department of Molecular Imaging & Therapy Austin Health Melbourne Victoria Australia.; Florey Department of Neurosciences & Mental Health The University of Melbourne Melbourne Parkville Australia.; The Australian Dementia Network (ADNeT) Melbourne Victoria Australia., Bourgeat P; Health and Biosecurity Flagship The Australian eHealth Research Centre CSIRO Brisbane Queensland Australia., Lopresti B; Department of Radiology University of Pittsburgh Pittsburgh Pennsylvania USA., Huang K; Department of Molecular Imaging & Therapy Austin Health Melbourne Victoria Australia., Krishnadas N; Department of Molecular Imaging & Therapy Austin Health Melbourne Victoria Australia.; Florey Institute of Neurosciences & Mental Health Parkville Victoria Australia., Fripp J; Health and Biosecurity Flagship The Australian eHealth Research Centre CSIRO Brisbane Queensland Australia., Takado Y; Department of Functional Brain Imaging National Institutes for Quantum and Radiological Science and Technology Chiba Japan., Gogola A; Department of Radiology University of Pittsburgh Pittsburgh Pennsylvania USA., Minhas D; Department of Radiology University of Pittsburgh Pittsburgh Pennsylvania USA., Weimer R; Genentech Inc. South San Francisco California USA., Higuchi M; Department of Functional Brain Imaging National Institutes for Quantum and Radiological Science and Technology Chiba Japan., Stephens A; Life Molecular Imaging GmbH Berlin Germany., Hansson O; Clinical Memory Research Unit Department of Clinical Sciences Lund University Malmö Sweden.; Memory Clinic Skåne University Hospital Malmö Sweden., Doré V; Department of Molecular Imaging & Therapy Austin Health Melbourne Victoria Australia.; Health and Biosecurity Flagship The Australian eHealth Research Centre CSIRO Heidelberg Victoria Australia.

Publikováno v: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2023 Jul 07; Vol. 15 (3), pp. e12454. Date of Electronic Publication: 2023 Jul 07 (Print Publication: 2023).

Imaging beta-amyloid (Aβ) burden in the brains of middle-aged individuals with alcohol-use disorders: a [ ¹¹ C]PIB PET study.

Autor: Flanigan MR; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA. flaniganm@upmc.edu., Royse SK; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA., Cenkner DP; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA., Kozinski KM; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA., Stoughton CJ; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA., Himes ML; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA., Minhas DS; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA., Lopresti B; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA., Butters MA; Department Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Narendran R; Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA.; Department Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

Publikováno v: Translational psychiatry [Transl Psychiatry] 2021 May 01; Vol. 11 (1), pp. 257. Date of Electronic Publication: 2021 May 01.