Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase

Autor: Erdmann, Nathan, Zhao, Jianxing, Lopez, Alicia L., Herek, Shelley, Curthoys, Norman, Hexum, Terry D., Tsukamoto, Takashi, Ferraris, Dana, Zheng, Jialin

Mononuclear phagocyte (macrophages and microglia) dysfunction plays a significant role in the pathogenesis of human immunodeficiency virus (HIV) associated dementia (HAD) through the production and release of soluble neurotoxic factors including glut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ccd26746440146d9e4dfb2391f8576be
https://europepmc.org/articles/PMC1976281/

Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: Linkage to HIV-1 associated dementia.

Autor: Jiangxing Zhao, Sumantra, Lopez, Alicia L., Erichsen, David, Herek, Shelley, Cotter, Robin L., Curthoys, Norman P., Jialin Zheng

Publikováno v: Journal of Neurochemistry; 1/1/2004, Vol. 88 Issue 1, p169-180, 12p

Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia.

Autor: Zhao J; Laboratory of Neurotoxicology at the Center for Neurovirology and Neurodegenerative Disorders Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198-5215, USA., Lopez AL, Erichsen D, Herek S, Cotter RL, Curthoys NP, Zheng J

Publikováno v: Journal of neurochemistry [J Neurochem] 2004 Jan; Vol. 88 (1), pp. 169-80.