Vascular Age as a Cardiovascular Risk Marker in Asymptomatic Patients with Type 2 Diabetes

Autor: Palma CCSSV, Lopes PM, Silva ELC, Bevilaqua MFM, Bomfim AS, Gomes MB

Publikováno v: Diabetes, Metabolic Syndrome and Obesity, Vol Volume 13, Pp 2505-2514 (2020)

Cátia Cristina Silva Sousa Vergara Palma,1 Pablo Moura Lopes,2 Eliete Leão Clemente Silva,1 Maria de Fátima da Matta Bevilaqua,1 Alfredo de Souza Bomfim,2 Marilia Brito Gomes1 1Department of Internal Medicine, Diabetes Unit, State University Hospi

Externí odkaz: https://doaj.org/article/e6f704fee2be4a0c8c287fceb23e7957

Insights of dietary electrolyte balance in broilers raised under natural heat stress conditions.

Autor: Moura FADS; Centro de Ciências Agrárias, Universidade Federal do Piauí - UFPI, Teresina, Brazil., Silva DRSE; Centro de Ciências Agrárias, Universidade Federal do Piauí - UFPI, Teresina, Brazil., Araújo RDS; Instituto de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso - UFMT, Pontal do Araguaia, Brazil., Ferreira GJBDC; Campus Professora Cinobelina Elvas, Universidade Federal do Piauí - UFPI, Bom Jesus, Brazil., Lopes PM; Centro de Ciências Agrárias, Universidade Federal do Piauí - UFPI, Teresina, Brazil., Silva SDC; Campus Professora Cinobelina Elvas, Universidade Federal do Piauí - UFPI, Bom Jesus, Brazil., Bezerra RM; Campus Professora Cinobelina Elvas, Universidade Federal do Piauí - UFPI, Bom Jesus, Brazil., Carvalho FLDA; Campus Professora Cinobelina Elvas, Universidade Federal do Piauí - UFPI, Bom Jesus, Brazil., Cardoso JDFS; Centro de Ciências Agrárias, Universidade Federal do Piauí - UFPI, Teresina, Brazil., Machado LP; Campus Realeza, Universidade Federal da Fronteira Sul - UFFS, Realeza, Parana, Brazil., Dourado LRB; Centro de Ciências Agrárias, Universidade Federal do Piauí - UFPI, Teresina, Brazil.

Publikováno v: British poultry science [Br Poult Sci] 2024 Oct 14, pp. 1-9. Date of Electronic Publication: 2024 Oct 14.

Arrhythmic Mitral Valve Prolapse Phenotype: An Unsupervised Machine Learning Analysis Using a Multicenter Cardiac MRI Registry.

Autor: Akyea RK; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Figliozzi S; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Lopes PM; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Bauer KB; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Moura-Ferreira S; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Tondi L; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Mushtaq S; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Censi S; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Pavon AG; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Bassi I; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Galian-Gay L; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Teske AJ; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Biondi F; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Filomena D; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Stylianidis V; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Torlasco C; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Muraru D; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Monney P; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Quattrocchi G; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Maestrini V; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Agati L; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Monti L; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Pedrotti P; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Vandenberk B; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Squeri A; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Lombardi M; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Ferreira AM; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Schwitter J; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Aquaro GD; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Pontone G; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Chiribiri A; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Rodríguez Palomares JF; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Yilmaz A; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Andreini D; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Florian AR; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Francone M; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Leiner T; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Abecasis J; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Badano LP; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Bogaert J; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Georgiopoulos G; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.)., Masci PG; From the Primary Care Stratified Medicine Research Group, Centre for Academic Primary Care, Lifespan and Population Health Unit, School of Medicine, University of Nottingham, Nottingham, England (R.K.A.); IRCCS Humanitas Research Hospital, Rozzano, Italy (S.F., L.M., M.F.); School of Biomedical Engineering and Imaging Sciences-Faculty of Life Sciences and Medicine, King's College London, Westminster Bridge Rd, London SE1 7EH, England (S.F., V.S., A.C., G.G., P.G.M.); Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Lisbon, Portugal (P.M.L., A.M.F., J.A.); Department of Cardiology, University Hospital Muenster, Muenster, Germany (K.B.B., A.Y., A.R.F.); Department of Cardiology, Hartcentrum, Jessa Hospital, Hasselt, Belgium (S.M.F.); Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (S.M.F.); Multimodality Cardiac Imaging Section, IRCSS Policlinico San Donato, San Donato Milanese, Italy (L.T., M.L.); Department of Radiology, Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy (L.T.); Department of Perioperative Cardiology and Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy (S.M., G.P.); GVM Care & Research, Maria Cecilia Hospital, Cotignola, Italy (S.C., A.S.); Center for Cardiac MR, Lausanne University Hospital, CHUV, Lausanne, Switzerland (A.G.P., P.M., J.S.); Cardiologia-4, Dipartimento Cardio-toraco-vascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy (I.B., G.Q., P.P.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (L.G.G., J.F.R.P.); Centro de Investigación Biomédica en Red, CIBERCV, Madrid, Spain (L.G.G., J.F.R.P.); Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (A.J.T., T.L.); Fondazione CNR/Regione Toscana G. Monasterio, Pisa, Italy (F.B., C.D.A.); Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (D.F., V.M., L.A.); Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy (C.T., D.M., L.P.B.); Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (D.M., L.P.B.); Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland (P.M., J.S.); Gasthuisberg University Hospital, Leuven, Belgium (B.V., J.B.); Department of Biomedical, Surgical and Dental Sciences (G.P.) and Department of Clinical Sciences and Community Health, Cardiovascular Section (D.A.), University of Milan, Milan, Italy; and Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece (G.G.).

Publikováno v: Radiology. Cardiothoracic imaging [Radiol Cardiothorac Imaging] 2024 Jun; Vol. 6 (3), pp. e230247.

The Influence of Lyophilization Pretreatment and Whey Content on Whey and Gelatin-Based Hydrogels.

Autor: Lopes PM; Physics and Chemistry Department, Technical University of Cluj-Napoca, 28 Memorandumului Street, 400114 Cluj-Napoca, Romania.; 'SAMUS' Special Vocational School, 17 Ialomiței Street, 400574 Cluj-Napoca, Romania., Fechete R; Physics and Chemistry Department, Technical University of Cluj-Napoca, 28 Memorandumului Street, 400114 Cluj-Napoca, Romania., Minteuan F; Physics and Chemistry Department, Technical University of Cluj-Napoca, 28 Memorandumului Street, 400114 Cluj-Napoca, Romania., Mare L; Physics and Chemistry Department, Technical University of Cluj-Napoca, 28 Memorandumului Street, 400114 Cluj-Napoca, Romania., Moldovan D; Physics and Chemistry Department, Technical University of Cluj-Napoca, 28 Memorandumului Street, 400114 Cluj-Napoca, Romania., Moldovan M; Polymeric Composite Laboratory, Institute of Chemistry 'Raluca Ripan', Babeș-Bolyai University, 30 Fântânele Street, 400294 Cluj-Napoca, Romania., Cuc S; Polymeric Composite Laboratory, Institute of Chemistry 'Raluca Ripan', Babeș-Bolyai University, 30 Fântânele Street, 400294 Cluj-Napoca, Romania., Saroși CL; Polymeric Composite Laboratory, Institute of Chemistry 'Raluca Ripan', Babeș-Bolyai University, 30 Fântânele Street, 400294 Cluj-Napoca, Romania., Popescu V; Physics and Chemistry Department, Technical University of Cluj-Napoca, 28 Memorandumului Street, 400114 Cluj-Napoca, Romania.

Publikováno v: Gels (Basel, Switzerland) [Gels] 2024 Mar 28; Vol. 10 (4). Date of Electronic Publication: 2024 Mar 28.

External validation of the unifying concept for the quantitative assessment of functional mitral regurgitation.

Autor: Lopes PM; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal. pedro_fagalopes@hotmail.com., Albuquerque F; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Freitas P; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Reis C; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Guerreiro S; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Abecasis J; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Trabulo M; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Ferreira AM; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Ribeiras R; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Mendes M; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal., Andrade MJ; Department of Cardiology, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Carnaxide, Lisbon, Portugal.

Publikováno v: The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2023 Nov; Vol. 39 (11), pp. 2139-2148. Date of Electronic Publication: 2023 Aug 02.