Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Looszova, A."'
Autor:
Eichenbaum, G., Zhou, J., De Smedt, A., De Jonghe, S., Looszova, A., Arien, T., Van Goethem, F., Vervoort, I., Shukla, U., Lammens, L.
Publikováno v:
In Journal of Pharmacological and Toxicological Methods November-December 2013 68(3):394-406
Autor:
Bianca Feyen, Adriana Looszova, Tim Erkens, Jill Witters, Liesbeth Van den Sande, Filip Verbraeken
Publikováno v:
Veterinary Clinical Pathology. 46:416-421
BACKGROUND A marked decrease in thrombocyte count was observed between subsequent measurements of the same EDTA blood sample in several minipigs, but little information was available explaining this finding. OBJECTIVES The objective was to evaluate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5471cbcf81aa8ec7a783b0127da49a22
https://doi.org/10.1111/vcp.12509
https://doi.org/10.1111/vcp.12509
Autor:
Sandy Thijssen, Sofie Starckx, Adriana Looszova, Geert Mannens, Ilham Smyej, Sandra De Jonghe, Tom Verhaeghe, Marie-Claude Rouan, Ann Lampo
Publikováno v:
Toxicologic pathology. 45(5)
Bedaquiline (BDQ) is an antibiotic to treat pulmonary multidrug-resistant tuberculosis (MDR-TB). Studies up to 39 weeks were conducted orally in dogs to assess the toxicity and pharmacokinetics of BDQ and its N-desmethyl metabolite (D-BDQ). Phospholi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925cefd774175f9c4f8da214b2717b26
https://pubmed.ncbi.nlm.nih.gov/28789609
https://pubmed.ncbi.nlm.nih.gov/28789609
Publikováno v:
In Parasitology International 2000 49(2):147-154
Autor:
Adriana Looszova, S. De Jonghe, I. Vervoort, Lieve Lammens, U. Shukla, A. De Smedt, F. Van Goethem, T. Arien, Gary Eichenbaum, J. Zhou
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:394-406
Introduction Evaluation of infusion site tolerability is required for the development of intravenous formulations of New Molecular Entities and is of particular importance for investigational drugs that have the potential to precipitate on contact wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d67be3dfc84cda08419f9dacff0ab27
https://doi.org/10.1016/j.vascn.2013.08.002
https://doi.org/10.1016/j.vascn.2013.08.002
Autor:
Adriana Looszova, Ann Lampo, Sofie Starckx, Nick Goeminne, Petra Vinken, Manisha Sonee, Loes Versmissen, Kristel Buyens, Erio Barale-Thomas
Publikováno v:
Toxicologic Pathology. 40:1049-1062
The kidney is one of the main targets of drug toxicity, and early detection of renal damage is critical in preclinical drug development. A model of cisplatin-induced nephrotoxicity in male Sprague Dawley rats treated for 1, 3, 5, 7, or 14 days at 1 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd190fd8bba126d473e98dc21f2c4eac
https://doi.org/10.1177/0192623312444765
https://doi.org/10.1177/0192623312444765
Autor:
Kathleen Van den Bulck, Siegrid Damsch, Gary Eichenbaum, Elaine Knight, Alfred Tonelli, L. Lammens, Bianca Feyen, Adriana Looszova, Kelley Michael F
Publikováno v:
Toxicologic Pathology. 39:337-347
In a three-week oral gavage toxicity study in rats, a high incidence of respiratory symptoms and high mortality was noted in compound-dosed rats only. Because of audible respiration, an effect in the upper respiratory tract was suspected and the nasa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdeb0670f86d8562e44e032636d30290
https://doi.org/10.1177/0192623310388430
https://doi.org/10.1177/0192623310388430
Autor:
Gary Eichenbaum, Alfred Tonelli, V. Hillsamer, Kelley Michael F, Siegrid Damsch, K. Van den Bulck, Anton Megens, Elaine Knight, John Vandenberghe, Adriana Looszova, Karen Roels, L. Lammens, Bianca Feyen
Publikováno v:
Journal of Applied Toxicology. 31:342-354
Unscheduled mortality preceded by adverse respiratory clinical signs in rats dosed by oral gavage may not only be caused by technical gavage error or systemic toxicity but may also be caused by gastro-esophageal reflux and subsequent aspiration of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2ff8971b43cae218cee5942d7eda914
https://doi.org/10.1002/jat.1592
https://doi.org/10.1002/jat.1592
Autor:
Lieven Baert, Marie-Paule Bouche, Eva Hoeben, Gerben Albert Eleutherius Van 'T Klooster, Frans van Velsen, Adriana Looszova, Herman Borghys
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:2042-2050
The next-generation human immunodeficiency virus type 1 (HIV-1) nonnucleoside reverse transcriptase inhibitor rilpivirine (TMC278) was administered in rats and dogs as single intramuscular (IM) or subcutaneous (SC) injections, formulated as a 200-nm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07f3562334572eae11faee2cc2bc1f3
https://doi.org/10.1128/aac.01529-09
https://doi.org/10.1128/aac.01529-09
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