Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

Autor: Bailey, JNC, Loomis, SJ, Kang, JH, Allingham, RR, Gharahkhani, P, Khor, CC, Burdon, KP, Aschard, H, Chasman, DI, Igo, RP, Hysi, PG, Glastonbury, CA, Ashley-Koch, A, Brilliant, M, Brown, AA, Budenz, DL, Buil, A, Cheng, CY, Choi, H, Christen, WG, Curhan, G, De Vivo, I, Fingert, JH, Foster, PJ, Fuchs, C, Gaasterland, D, Gaasterland, T, Hewitt, AW, Hu, F, Hunter, DJ, Khawaja, AP, Lee, RK, Li, Z, Lichter, PR, Mackey, DA, McGuffin, P, Mitchell, P, Moroi, SE, Perera, SA, Pepper, KW, Qi, Q, Realini, T, Richards, JE, Ridker, PM, Rimm, E, Ritch, R, Ritchie, M, Schuman, JS, Scott, WK, Singh, K, Sit, AJ, Song, YE, Tamimi, RM, Topouzis, F, Viswanathan, AC, Verma, SS, Vollrath, D, Wang, JJ, Weisschuh, N, Wissinger, B, Wollstein, G, Wong, TY, Yaspan, BL, Zack, DJ, Zhang, K, Weinreb, RN, Pericak-Vance, MA, Small, K, Hammond, CJ, Aung, T, Liu, Y, Vithana, EN, MacGregor, S, Craig, JE, Kraft, P, Howell, G, Hauser, MA, Pasquale, LR

Publikováno v: Bailey, JNC; Loomis, SJ; Kang, JH; Allingham, RR; Gharahkhani, P; Khor, CC; et al.(2016). Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma. Nature Genetics, 48(2), 189-194. doi: 10.1038/ng.3482. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1sh4p2w9

© 2016 Nature America, Inc. Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. To identify new susceptibility loci, we performed meta-analysis on genome-wide association study (GWAS) results from eight independent studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0dcfbd0062b24171ab7afeacfac4f9d0
http://www.escholarship.org/uc/item/1sh4p2w9

Characterizing Common and Rare Variations in Nontraditional Glycemic Biomarkers Using Multivariate Approaches on Multiancestry ARIC Study.

Autor: Ray D; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD., Loomis SJ; Biogen Inc., Cambridge, MA., Venkataraghavan S; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD., Zhang J; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD., Tin A; School of Medicine, University of Mississippi Medical Center, Jackson, MS., Yu B; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX., Chatterjee N; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD., Selvin E; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.; Welch Center for Prevention, Epidemiology, & Clinical Research, Johns Hopkins University, Baltimore, MD., Duggal P; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.

Publikováno v: Diabetes [Diabetes] 2024 Sep 01; Vol. 73 (9), pp. 1537-1550.

Genome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials.

Autor: Loomis SJ; Biogen, Cambridge, MA, USA. stephanie.loomis@biogen.com., Sadhu N; Biogen, Cambridge, MA, USA., Fisher E; Biogen, Cambridge, MA, USA., Gafson AR; Biogen, Cambridge, MA, USA., Huang Y; Biogen, Cambridge, MA, USA., Yang C; Biogen, Cambridge, MA, USA., Hughes EE; Biogen, Cambridge, MA, USA., Marshall E; Biogen, Cambridge, MA, USA., Herman A; Genentech, South San Francisco, CA, USA., John S; Biogen, Cambridge, MA, USA., Runz H; Biogen, Cambridge, MA, USA., Jia X; Genentech, South San Francisco, CA, USA., Bhangale T; Genentech, South San Francisco, CA, USA., Bronson PG; Biogen, Cambridge, MA, USA.

Publikováno v: Scientific reports [Sci Rep] 2023 Aug 31; Vol. 13 (1), pp. 14313. Date of Electronic Publication: 2023 Aug 31.

Genetic map of regional sulcal morphology in the human brain from UK biobank data.

Autor: Sun BB; Translational Biology, Research & Development, Biogen Inc., Cambridge, MA, US. bbsun92@outlook.com.; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. bbsun92@outlook.com., Loomis SJ; Translational Biology, Research & Development, Biogen Inc., Cambridge, MA, US., Pizzagalli F; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, Turin, Italy.; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Shatokhina N; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Painter JN; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Foley CN; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.; Optima Partners, Edinburgh, UK., Jensen ME; Clinical Sciences, Research & Development, Biogen Inc., Cambridge, MA, US., McLaren DG; Clinical Sciences, Research & Development, Biogen Inc., Cambridge, MA, US., Chintapalli SS; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, US., Zhu AH; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Dixon D; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Islam T; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Ba Gari I; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US., Runz H; Translational Biology, Research & Development, Biogen Inc., Cambridge, MA, US., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Thompson PM; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US. pthomp@usc.edu., Jahanshad N; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, US. njahansh@usc.edu., Whelan CD; Translational Biology, Research & Development, Biogen Inc., Cambridge, MA, US. christopherdwhelan@outlook.com.

Publikováno v: Nature communications [Nat Commun] 2022 Oct 14; Vol. 13 (1), pp. 6071. Date of Electronic Publication: 2022 Oct 14.

Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study.

Autor: Loomis SJ; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA., Köttgen A; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Institute of Genetic Epidemiology, Medical Center and Faculty of Medicine - University of Freiburg, Freiburg, Germany., Li M; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Division of Nephrology and Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA., Tin A; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA., Coresh J; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Welch Center for Prevention, Epidemiology, & Clinical Research, The Johns Hopkins University, Baltimore, MD, USA., Boerwinkle E; Department of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health at Houston, Houston, TX, USA., Gibbs R; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Muzny D; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Pankow J; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA., Selvin E; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.; Welch Center for Prevention, Epidemiology, & Clinical Research, The Johns Hopkins University, Baltimore, MD, USA., Duggal P; Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA. pduggal@jhu.edu.

Publikováno v: Scientific reports [Sci Rep] 2019 Apr 11; Vol. 9 (1), pp. 5941. Date of Electronic Publication: 2019 Apr 11.