Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Loo Chien Wang"'
Autor:
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/e0617b1d20174c67b17340e2ad076255
Autor:
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract Epitranscriptomic RNA modifications are crucial for the maintenance of glioma stem cells (GSCs), the most malignant cells in glioblastoma (GBM). 3-methylcytosine (m3C) is a new epitranscriptomic mark on RNAs and METTL8 represents an m3C writ
Externí odkaz:
https://doaj.org/article/1d37dfa6251d462ab7c00e54f1198368
Autor:
Yu Xing Teo, Kah Yin Lee, Corinna Jie Hui Goh, Loo Chien Wang, Radoslaw M. Sobota, Keng-Hwee Chiam, Chan Du, Andrew C. A. Wan
Publikováno v:
npj Science of Food, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Cell-adhesive factors mediate adhesion of cells to substrates via peptide motifs such as the Arg–Gly–Asp (RGD) sequence. With the onset of sustainability issues, there is a pressing need to find alternatives to animal-derived cell-adhesi
Externí odkaz:
https://doaj.org/article/8ee9be7ee6254bdfb90010f6d6f9b10f
Autor:
Ginny Xiaohe Li, Tianyun Zhao, Loo Chien Wang, Hyungwon Choi, Yan Ting Lim, Radoslaw M. Sobota
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Kinase inhibitors often exert on/off-target effects, and efficient data analysis is essential for assessing these effects on the proteome. We developed a workflow for rapidly performing such a proteomic assessment, termed as kinase inhibitor
Externí odkaz:
https://doaj.org/article/324e213606e84eb3bb6459358bbbee46
Autor:
Sharanjeet Atwal, Jantana Wongsantichon, Suparat Giengkam, Kittirat Saharat, Yanin Jaiyen Pittayasathornthun, Suthida Chuenklin, Loo Chien Wang, Taerin Chung, Hyun Huh, Sang-Hyuk Lee, Radoslaw M. Sobota, Jeanne Salje
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Orientia tsutsugamushi (Ot) the causing agent of scrub typhus exits infected cells using a unique mechanism that involves budding off the surface of infected cells. Here, Atwal et al. report that Ots that have budded from their host cells are in a di
Externí odkaz:
https://doaj.org/article/72fbb203e5de497e9b9d0560c9abc8fe
Autor:
Bozena Mika-Gospodorz, Suparat Giengkam, Alexander J. Westermann, Jantana Wongsantichon, Willow Kion-Crosby, Suthida Chuenklin, Loo Chien Wang, Piyanate Sunyakumthorn, Radoslaw M. Sobota, Selvakumar Subbian, Jörg Vogel, Lars Barquist, Jeanne Salje
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Studying emerging pathogens is often challenging due to the lack of information. Here the authors show that dual RNA-seq, profiling the host and pathogen transcriptome simultaneously, helps uncovering the biology of Orientia tsutsugamushi, a major ca
Externí odkaz:
https://doaj.org/article/46adddfa7d4548f68077abbc70f1fb90
Autor:
Shan Zhang, Boris Reljić, Chao Liang, Baptiste Kerouanton, Joel Celio Francisco, Jih Hou Peh, Camille Mary, Narendra Suhas Jagannathan, Volodimir Olexiouk, Claire Tang, Gio Fidelito, Srikanth Nama, Ruey-Kuang Cheng, Caroline Lei Wee, Loo Chien Wang, Paula Duek Roggli, Prabha Sampath, Lydie Lane, Enrico Petretto, Radoslaw M. Sobota, Suresh Jesuthasan, Lisa Tucker-Kellogg, Bruno Reversade, Gerben Menschaert, Lei Sun, David A. Stroud, Lena Ho
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Small open reading frame-encoded peptides (SEPs), shorter than 100 amino acids, are involved in many cell biological processes. Here the authors identify 16 nuclear-encoded mitochondrial SEPs, including BRAWNIN, an essential regulator of respiratory
Externí odkaz:
https://doaj.org/article/0910631e426f49c8a20e80729e44b71d
Autor:
Xiaosai Yao, Jing Han Hong, Amrita M. Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, James Qu, Xiu Yi Kwek, Jeffrey Chun Tatt Lim, Wen Fong Ooi, Joanna Koh, Zhenxun Wang, You-Fu Pan, Yan Shan Ong, Kiat-Yi Tan, Jian Yuan Goh, Sheng Rong Ng, Luca Pignata, Dachuan Huang, Alexander Lezhava, Su Ting Tay, Minghui Lee, Xun Hui Yeo, Wai Leong Tam, Sun Young Rha, Shang Li, Ernesto Guccione, Andrew Futreal, Jing Tan, Joe Poh Sheng Yeong, Wanjin Hong, Robert Yauch, Kenneth Tou-En Chang, Radoslaw M. Sobota, Patrick Tan, Bin Tean Teh
Publikováno v:
Nature Cell Biology. 25:765-777
Autor:
Mukul Prasad, Sashigala Ponnalagu, Qun Zeng, Khang Luu, Si Min Lang, Hiu Yi Wong, Man Si Cheng, Meihui Wu, Karthik Mallilankaraman, Radoslaw Mikolaj Sobota, Yan Ting Lim, Loo Chien Wang, Chuan Keng Goh, Kai Xun Joshua Tay, Kwok Seng Loh, Cheng-I. Wang, Wen-Hsien Lee, Boon Cher Goh, Chwee Ming Lim, Herbert Schwarz
Publikováno v:
Cancer Immunology, Immunotherapy. 71:2583-2596
Non-keratinizing nasopharyngeal carcinoma (NPC) is a malignancy with a poor prognosis for relapsing patients and those with metastatic disease. Here, we identify a novel disease mechanism of NPC which may be its Achilles' heel that makes it susceptib
Autor:
Xiaosai Yao, Jing Han Hong, Amrita Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, Robert Yauch, Kenneth Tou-En Chang, Radoslaw M. Sobota, Patrick Tan, Bin Tean Teh
Publikováno v:
Cancer Research. 83:1494-1494
PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and the inactivation of PBRM1 is the second most frequent mutational event in kidney tumorigenesis. However, the impact of PBRM1 loss on chromatin remodeling, espec