Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Loni Perrenoud"'
Autor:
Loni Perrenoud, Nicholas T. Kruse, Emily Andrews, Zhiying You, Michel Chonchol, Chaorong Wu, Patrick Ten Eyck, Diana Zepeda-Orozco, Diana Jalal
Publikováno v:
Kidney Medicine, Vol 2, Iss 2, Pp 155-161 (2020)
Rationale & Objective: Hyperuricemia is associated with chronic kidney disease (CKD) progression. We evaluated whether lowering serum uric acid levels improves levels of biomarkers of kidney damage. Study Design: Post hoc analysis of clinical trial p
Externí odkaz:
https://doaj.org/article/c305eeef60bb4abfa54db6bcee71ad66
Autor:
Diana Jalal, Brandon Renner, Jennifer Laskowski, Erik Stites, James Cooper, Karissa Valente, Zhiying You, Loni Perrenoud, Moglie Le Quintrec, Ismaeel Muhamed, Uwe Christians, Jelena Klawitter, Margaret A. Lindorfer, Ronald P. Taylor, V. Michael Holers, Joshua M. Thurman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 14 (2018)
Background Endothelial microparticles are associated with chronic kidney disease (CKD) and complement activation. We hypothesized that the complement pathway is activated in patients with CKD via endothelial microparticles and that complement activat
Externí odkaz:
https://doaj.org/article/ae86a962727a40ada0ea3f4ae28824e4
Autor:
Emily S Andrews, Loni Perrenoud, Kristen L Nowak, Zhiying You, Andreas Pasch, Michel Chonchol, Jessica Kendrick, Diana Jalal
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205831 (2018)
BACKGROUND:Chronic kidney disease (CKD)-mineral and bone disorder (MBD) is a systemic disorder that leads to vascular calcification and accelerated atherosclerosis. Uric acid has been shown to associate with vascular calcification and with carotid in
Externí odkaz:
https://doaj.org/article/a0b81b277a0141f5ab8443622266ab9c
Autor:
Antonio Jimeno, Rene Gonzalez, Dennis R. Roop, William Robinson, Jing H. Wang, Xiao-Jing Wang, Theresa Medina, Hilary Somerset, Aik-Choon Tan, Dexiang Gao, Randi Yeager, Bettina Miller, Karina Gomez, Cera Nieto, Phuong N. Le, Loni Perrenoud, Julie Reisinger, Tugs-Saikhan Chimed, Stephen B. Keysar, Nathaniel Alzofon, J. Jason Morton
Resistance to immunotherapy is a significant challenge, and the scarcity of human models hinders the identification of the underlying mechanisms. To address this limitation, we constructed an autologous humanized mouse (aHM) model with hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655a6f1c1b66b2ca94647218902d75a6
https://doi.org/10.1158/1541-7786.c.6545108.v1
https://doi.org/10.1158/1541-7786.c.6545108.v1
Autor:
Antonio Jimeno, Rene Gonzalez, Dennis R. Roop, William Robinson, Jing H. Wang, Xiao-Jing Wang, Theresa Medina, Hilary Somerset, Aik-Choon Tan, Dexiang Gao, Randi Yeager, Bettina Miller, Karina Gomez, Cera Nieto, Phuong N. Le, Loni Perrenoud, Julie Reisinger, Tugs-Saikhan Chimed, Stephen B. Keysar, Nathaniel Alzofon, J. Jason Morton
Table S1. Expanded HSPC engraftment into mouse cohorts Table S2. Human immune cell presence in HM tissues Table S3a. CUHM003 mutations present at diagnosis b. Additional CUHM003 mutations present at progression c. CUHM005 mutations present at diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3fbcf5bdeea96081d6cb3e0e4b08c
https://doi.org/10.1158/1541-7786.22526474.v1
https://doi.org/10.1158/1541-7786.22526474.v1
Publikováno v:
Journal of visualized experiments : JoVE. (190)
Calcium influx in response to T-cell receptor stimulation is a common measure of T-cell signaling. Several calcium indicator dyes have been developed to assess calcium signaling by band-pass flow cytometry. This protocol is designed to measure calciu
Autor:
Hilary Somerset, William A. Robinson, Bettina Miller, Julie Reisinger, Tugs-Saikhan Chimed, Antonio Jimeno, Phuong Le, John Morton, Rene Gonzalez, Cera Nieto, Randi Yeager, Loni Perrenoud, Xiao-Jing Wang, Stephen B. Keysar, Dennis R. Roop, Karina E. Gomez, Jing Wang, Dexiang Gao, Aik Choon Tan, Nathaniel Alzofon, Theresa Medina
Publikováno v:
Mol Cancer Res
Molecular cancer research : MCR, vol 19, iss 2
Molecular cancer research : MCR, vol 19, iss 2
Resistance to immunotherapy is a significant challenge, and the scarcity of human models hinders the identification of the underlying mechanisms. To address this limitation, we constructed an autologous humanized mouse (aHM) model with hematopoietic
Autor:
Lama Noureddine, Berenice Gitomer, Diana Jalal, Wei Wang, Michel Chonchol, Benjamin R. Griffin, Loni Perrenoud, Zhiying You
Publikováno v:
Am J Nephrol
Background: Cyst compression of renal tubules plays a role in the progression of autosomal dominant polycystic kidney disease (ADPKD) and may induce expression of kidney injury molecule-1 (KIM-1). Whether urinary KIM-1 indexed for creatinine (uKIM-1/
Autor:
Loni Perrenoud, Eric T. Clambey, Leslie J. Berg, Diana L. Bonilla, Julianne B. Riggs, Linda F. van Dyk, Eva M. Medina
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology
Frontiers in Microbiology
Investigating the dynamics of virus-host interactions in vivo remains an important challenge, often limited by the ability to directly identify virally-infected cells. Here, we combine detection of a beta-lactamase activated fluorescent substrate wit
Autor:
Chaorong Wu, Zhiying You, Emily Andrews, Loni Perrenoud, Diana Jalal, Diana Zepeda-Orozco, Nicholas T. Kruse, Patrick Ten Eyck, Michel Chonchol
Publikováno v:
Kidney Medicine
Kidney Medicine, Vol 2, Iss 2, Pp 155-161 (2020)
Kidney Medicine, Vol 2, Iss 2, Pp 155-161 (2020)
Rationale & Objective Hyperuricemia is associated with chronic kidney disease (CKD) progression. We evaluated whether lowering serum uric acid levels improves levels of biomarkers of kidney damage. Study Design Post hoc analysis of clinical trial par