Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Longze Sha"'
Autor:
Yan Yang, Shihong Xu, Yu Deng, Yaoyao Liu, Kui Zhang, Shiya Lv, Longze Sha, Qi Xu, Xinxia Cai, Jinping Luo
Publikováno v:
Nanotechnology and Precision Engineering, Vol 7, Iss 2, Pp 023001-023001-10 (2024)
To enable the detection and modulation of modularized neural networks in vitro, this study proposes a microfluidic microelectrode array chip for the cultivation, compartmentalization, and control of neural cells. The chip was designed based on the sp
Externí odkaz:
https://doaj.org/article/058d4e7481a4487789854d8b1a4bbc9a
Autor:
Longze Sha, Jing Li, Hui Shen, Qingyu Wang, Peixin Meng, Xiuneng Zhang, Yu Deng, Wanwan Zhu, Qi Xu
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112975- (2023)
Summary: In bacteria, archaea, protists, and plants, the hydrolysis of pyrophosphate (PPi) by inorganic pyrophosphatase (PPase) can, under stress conditions, substitute for ATP-driven proton flux to generate a proton gradient and induce luminal acidi
Externí odkaz:
https://doaj.org/article/abe5d0e4a20549d18a0fbd73f9592659
Autor:
Dan Lei, Chenhui Mao, Jie Li, Xinying Huang, Longze Sha, Caiyan Liu, Liling Dong, Qi Xu, Jing Gao
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
IntroductionAlzheimer's disease (AD) is one of the highly concerned degenerative disorders in recent decades. Though vast amount of researches has been done in various aspects, early-onset subtype, however, needs more investigation in diagnosis for i
Externí odkaz:
https://doaj.org/article/885b38ebc4de4e5c85a0790d3fd303a1
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Dysregulation of excitatory amino acid transporter 2 (EAAT2) contributes to the development of temporal lobe epilepsy (TLE). Several strategies for increasing total EAAT2 levels have been proposed. However, the mechanism underlying the oligomeric ass
Externí odkaz:
https://doaj.org/article/f09b3df47e9e4fecb6fbd133eee398ba
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Amyloid-β (Aβ) derived from amyloid precursor protein (APP) hydrolysis is acknowledged as the predominant hallmark of Alzheimer’s disease (AD) that especially correlates to genetics and daily activities. In 2019, meta-analysis of AD has discovere
Externí odkaz:
https://doaj.org/article/d9607a964a8148df95fac57d766f138b
Autor:
Liling Dong, Jie Li, Caiyan Liu, Chenhui Mao, Jie Wang, Dan Lei, Xinying Huang, Shanshan Chu, Bo Hou, Feng Feng, Longze Sha, Qi Xu, Jing Gao
Publikováno v:
Brain and Behavior, Vol 11, Iss 11, Pp n/a-n/a (2021)
Abstract Introduction To investigate the heterogeneous effect of Apolipoprotein E (ApoE) genotype on clinical phenotypes in early‐onset Alzheimer's disease (EOAD) and late‐onset Alzheimer's disease (LOAD), respectively. Methods 785 probable AD pa
Externí odkaz:
https://doaj.org/article/76fb68c2db6742f3a15dff6ad5473f97
Autor:
Shihong Xu, Yu Deng, Jinping Luo, Yaoyao Liu, Enhui He, Yan Yang, Kui Zhang, Longze Sha, Yuchun Dai, Tao Ming, Yilin Song, Luyi Jing, Chengyu Zhuang, Qi Xu, Xinxia Cai
Publikováno v:
Biosensors, Vol 12, Iss 7, p 546 (2022)
Both the cellular- and population-level properties of involved neurons are essential for unveiling the learning and memory functions of the brain. To give equal attention to these two aspects, neural sensors based on microelectrode arrays (MEAs) have
Externí odkaz:
https://doaj.org/article/711c1f00242246f78e8ad39ad4862b70
Autor:
Caiyan Liu, Liling Dong, Jie Wang, Jie Li, Xinying Huang, Dan Lei, Chenhui Mao, Shanshan Chu, Longze Sha, Qi Xu, Bin Peng, Liying Cui, Jing Gao
Publikováno v:
Journal of Medical Genetics; Jun2024, Vol. 61 Issue 6, p543-3, 9p
Autor:
Yan Yang, Yu Deng, Shihong Xu, Yaoyao Liu, Wei Liang, Kui Zhang, Shiya Lv, Longze Sha, Huabing Yin, Yirong Wu, Jinping Luo, Qi Xu, Xinxia Cai
Publikováno v:
ACS Applied Bio Materials.
Autor:
Liling, Dong, Caiyan, Liu, Longze, Sha, Chenhui, Mao, Jie, Li, Xinying, Huang, Jie, Wang, Shanshan, Chu, Bin, Peng, Liying, Cui, Qi, Xu, Jing, Gao
Publikováno v:
Journal of Alzheimer's Disease. 87:1549-1556
Background: The established causative mutations in the APP, PSEN1, and PSEN2 can explain less than 1%,Alzheimer’s disease (AD) patients. Of the identified variants, the PSEN2 mutations are even less common. Objective: With the genetic study from th