Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Longwei Liu"'
Autor:
Wei Lin, Abhishek Phatarphekar, Yanghao Zhong, Longwei Liu, Hyung-Bae Kwon, William H. Gerwick, Yingxiao Wang, Sohum Mehta, Jin Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Protein kinases are key signaling nodes that regulate fundamental biological and disease processes. Illuminating kinase signaling from multiple angles can provide deeper insights into disease mechanisms and improve therapeutic targeting. Whi
Externí odkaz:
https://doaj.org/article/49a78535a69f45c58c536552c2eedf29
Publikováno v:
Geo-spatial Information Science, Pp 1-23 (2024)
Street space is a crucial component of public space, serving as a site for a variety of human activities. However, prior studies have primarily focused on the traffic function of street space, neglecting other functional types, such as residential an
Externí odkaz:
https://doaj.org/article/7bacfa29034d4ff59cc851adda33b196
Autor:
Min Tang, Shan Jiang, Xiaoming Huang, Chunxia Ji, Yexin Gu, Ying Qi, Yi Xiang, Emmie Yao, Nancy Zhang, Emma Berman, Di Yu, Yunjia Qu, Longwei Liu, David Berry, Yu Yao
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-20 (2024)
Abstract Glioma, with its heterogeneous microenvironments and genetic subtypes, presents substantial challenges for treatment prediction and development. We integrated 3D bioprinting and multi-algorithm machine learning as a novel approach to enhance
Externí odkaz:
https://doaj.org/article/3e4bee0b7ab14039a078e569d6888c3c
Autor:
Min Tang, Yunjia Qu, Peixiang He, Emmie Yao, Tianze Guo, Di Yu, Nancy Zhang, Wisarut Kiratitanaporn, Yazhi Sun, Longwei Liu, Yingxiao Wang, Shaochen Chen
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101077- (2024)
Glioblastoma (GBM) presents a significant therapeutic challenge due to the limited efficacy of existing treatments. Chimeric antigen receptor (CAR) T-cell therapy offers promise, but its potential in solid tumors like GBM is undermined by the physica
Externí odkaz:
https://doaj.org/article/11d68e80b15e43d597f81d21b94df673
Autor:
Longwei Liu, Yunjia Qu, Leonardo Cheng, Chi Woo Yoon, Peixiang He, Abdula Monther, Tianze Guo, Sarah Chittle, Yingxiao Wang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 12, Pp n/a-n/a (2022)
Abstract Cell‐based immunotherapy, for example, chimeric antigen receptor T (CAR‐T) cell immunotherapy, has revolutionized cancer treatment, particularly for blood cancers. However, factors such as insufficient T cell tracking, tumour heterogenei
Externí odkaz:
https://doaj.org/article/a5920c142693400580994f2ef7e0798a
Autor:
Longwei Liu, Praopim Limsakul, Xianhui Meng, Yan Huang, Reed E. S. Harrison, Tse-Shun Huang, Yiwen Shi, Yiyan Yu, Krit Charupanit, Sheng Zhong, Shaoying Lu, Jin Zhang, Shu Chien, Jie Sun, Yingxiao Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Existing Förster Resonance Energy Transfer (FRET) biosensors are often limited in their sensitivity. Here the authors report FRET-seq which they use to identify Fyn and ZAP70 kinase biosensors with enhanced performance, and use them to image T-cell
Externí odkaz:
https://doaj.org/article/bb6ff210871349e99294dd89352b8506
Autor:
Yiqian Wu, Ziliang Huang, Reed Harrison, Longwei Liu, Linshan Zhu, Yinglin Situ, Yingxiao Wang
Publikováno v:
APL Bioengineering, Vol 6, Iss 1, Pp 011502-011502-14 (2022)
Despite its success in treating hematologic malignancies, chimeric antigen receptor (CAR) T cell therapy faces two major challenges which hinder its broader applications: the limited effectiveness against solid tumors and the nonspecific toxicities.
Externí odkaz:
https://doaj.org/article/facffa305d9348b1a17421738fe07b7e
Publikováno v:
Plants, Vol 11, Iss 15, p 1926 (2022)
Ammanniaauriculata is a troublesome broadleaf weed, widely distributed in the paddy fields of southern China. In this study, 10 biotypes of A. auriculata were sampled from Yangzhou City, China, where the paddy fields were seriously infested with A. a
Externí odkaz:
https://doaj.org/article/c37b31adae21454093cf11ae91d0ff81
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Extensive studies have shown that cells can sense and modulate the biomechanical properties of the ECM within their resident microenvironment. Thus, targeting the mechanotransduction signaling pathways provides a promising way for disease interventio
Externí odkaz:
https://doaj.org/article/ec820a157da041df84f4a328c712fa73
Publikováno v:
ACS Central Science. 9:593-596