Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Longsheng Lai"'
Autor:
Eric H.-L. Chen, Chun-Hsiung Wang, Yi-Ting Liao, Feng-Yueh Chan, Yui Kanaoka, Takayuki Uchihashi, Koichi Kato, Longsheng Lai, Yi-Wei Chang, Meng-Chiao Ho, Rita P.-Y. Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The abuse of antibiotics has led to the emergence of multidrug-resistant microbial pathogens, presenting a pressing challenge in global healthcare. Membrane-disrupting antimicrobial peptides (AMPs) combat so-called superbugs via mechanisms d
Externí odkaz:
https://doaj.org/article/77ddcb9b73dc4a1a9df003d2347f0c69
Autor:
Wenjie Chen, Yiping Chen, Wenjing Cheng, Peng Li, Junliang Shen, Tao Tong, Longsheng Lai, Simin Yan, Zichun Huang, Jiawei Li, Shuqiong Huang, Xianjun Meng
Publikováno v:
Biochemical and Biophysical Research Communications. 646:86-95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b899578ef74d4da27fe233fc5cc661a0
https://doi.org/10.1016/j.bbrc.2023.01.046
https://doi.org/10.1016/j.bbrc.2023.01.046
Autor:
Longsheng Lai, Yee-Wai Cheung, Matthew Martinez, Kathryn Kixmoeller, Leon Palao, Stefan Steimle, Meng-Chiao Ho, Ben E. Black, Erh-Min Lai, Yi-Wei Chang
Publikováno v:
Methods in Molecular Biology ISBN: 9781071630594
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdad32b246bcfbc1fd094444439dc201
https://doi.org/10.1007/978-1-0716-3060-0_18
https://doi.org/10.1007/978-1-0716-3060-0_18
Publikováno v:
Journal of Biological Chemistry. 283:9318-9327
Chemical modification to improve biopharmaceutical properties, especially oral absorption and bioavailability, is a common strategy employed by pharmaceutical chemists. The approach often employs a simple structural modification and utilizes ubiquito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b19f7ea6c8c174a4e4879be73a56ffc
https://doi.org/10.1074/jbc.m709530200
https://doi.org/10.1074/jbc.m709530200
Publikováno v:
Proteins: Structure, Function, and Genetics. 44:321-328
This report describes the application of a simple computational tool, AAPAIR.TAB, for the systematic analysis of the cysteine-rich EGF, Sushi, and Laminin motif/sequence families at the two-amino acid level. Automated dipeptide frequency/bias analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f295ff5ce799b5143763ad15595b2214
https://doi.org/10.1002/prot.1097
https://doi.org/10.1002/prot.1097
Publikováno v:
Molecular pharmaceutics. 7(6)
Human valacyclovirase (hVACVase) is a prodrug-activating enzyme for amino acid prodrugs including the antiviral drugs valacyclovir and valganciclovir. In hVACVase-catalyzed reactions, the leaving group of the substrate corresponds to the drug moiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f271df4ef0bc03c850e1bc2e8e0fa989
https://pubmed.ncbi.nlm.nih.gov/21028903
https://pubmed.ncbi.nlm.nih.gov/21028903
Autor:
Longsheng Lai1,2, Zhaohui Xu3,4 zhaohui@umich.edu, Jiahai Zhou3,4, Kyung-Dall Lee1,2, Amidon, Gordon L.1,2 glamidon@umich.edu
Publikováno v:
Journal of Biological Chemistry. 4/4/2008, Vol. 283 Issue 14, p9318-9327. 10p. 5 Diagrams, 2 Charts.