Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Longping V Tse"'
Autor:
Rita M Meganck, Deanna Zhu, Stephanie Dong, Lisa J Snoderly-Foster, Yago R Dalben, Devina Thiono, Laura J White, Arivianda M DeSilva, Ralph S Baric, Longping V Tse
Publikováno v:
eLife, Vol 12 (2023)
A hallmark of dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://doaj.org/article/052e2b8492e2439d954641c9e43adbfa
Autor:
Victoria J Madigan, Julianne A Yuziuk, Anna M Chiarella, Tyne O Tyson, Rita M Meganck, Zachary C Elmore, Longping V Tse, Nathaniel A Hathaway, Aravind Asokan
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007988 (2019)
Adeno-associated viruses (AAV) are Dependoparvoviruses that have shown promise as recombinant vectors for gene therapy. While infectious pathways of AAV are well studied, gaps remain in our understanding of host factors affecting vector genome expres
Externí odkaz:
https://doaj.org/article/fc7fbedd06ca440da188d4b61628143e
Autor:
Huatao Guo, Longping V Tse, Angela W Nieh, Elizabeth Czornyj, Steven Williams, Sabrina Oukil, Vincent B Liu, Jeff F Miller
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002414 (2011)
Diversity-generating retroelements (DGRs) are in vivo sequence diversification machines that are widely distributed in bacterial, phage, and plasmid genomes. They function to introduce vast amounts of targeted diversity into protein-encoding DNA sequ
Externí odkaz:
https://doaj.org/article/f06838c4f6d54e8d99df01a365f85838
Autor:
Rita M. Meganck, Caitlin E. Edwards, Michael L. Mallory, Rhianna E. Lee, Hong Dang, Alexis B. Bailey, Jason A. Wykoff, Samuel C. Gallant, Deanna R. Zhu, Boyd L. Yount, Takafumi Kato, Kendall M. Shaffer, Satoko Nakano, Anne Marie Cawley, Vishwaraj Sontake, Jeremy R. Wang, Robert S. Hagan, Melissa B. Miller, Purushothama Rao Tata, Scott H. Randell, Longping V. Tse, Camille Ehre, Kenichi Okuda, Richard C. Boucher, Ralph S. Baric
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114076- (2024)
Summary: The severe acute respiratory syndrome coronavirus 2 pandemic is characterized by the emergence of novel variants of concern (VOCs) that replace ancestral strains. Here, we dissect the complex selective pressures by evaluating variant fitness
Externí odkaz:
https://doaj.org/article/f8f7061e966c4c31ad0d17d536355449
Autor:
Ana C. Puhl, Ethan J. Fritch, Thomas R. Lane, Longping V. Tse, Boyd L. Yount, Carolina Q. Sacramento, Natalia Fintelman-Rodrigues, Tatyana Almeida Tavella, Fabio Trindade Maranhão Costa, Stuart Weston, James Logue, Matthew Frieman, Lakshmanane Premkumar, Kenneth H. Pearce, Brett L. Hurst, Carolina Horta Andrade, James A. Levi, Nicole J. Johnson, Samantha C. Kisthardt, Frank Scholle, Thiago Moreno L. Souza, Nathaniel John Moorman, Ralph S. Baric, Peter B. Madrid, Sean Ekins
Publikováno v:
ACS Omega, Vol 6, Iss 11, Pp 7454-7468 (2021)
Externí odkaz:
https://doaj.org/article/f5c5fda4ba7d411a9be4f5d7993c395f
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Emerging coronaviruses (CoV) are constant global public health threats to society. Multiple ongoing clinical trials for vaccines and antivirals against CoVs showcase the availability of medical interventions to both prevent and treat the future emerg
Externí odkaz:
https://doaj.org/article/fb10e439aeef47708bec3eaead6dddc7
Autor:
Rita M. Meganck, Deanna Zhu, Stephanie Dong, Lisa J. Snoderly-Foster, Yago R. Dalben, Devina Thiono, Laura J. White, Aravinda M. DeSilva, Ralph S. Baric, Longping V. Tse
Publikováno v:
bioRxiv
A hallmark of Dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ed5d83705e9b49ba9f8de7f86938f1
https://europepmc.org/articles/PMC10081285/
https://europepmc.org/articles/PMC10081285/
Autor:
Ellen Young, Boyd Yount, Petraleigh Pantoja, Sandra Henein, Rita M. Meganck, Jennifer McBride, Jennifer E. Munt, Thomas J. Baric, Deanna Zhu, Trevor Scobey, Stephanie Dong, Longping V. Tse, Melween I. Martinez, Armando G. Burgos, Rachel L. Graham, Laura White, Aravinda DeSilva, Carlos A. Sariol, Ralph S. Baric
Publikováno v:
Nature Communications. 14
The four dengue virus serotypes co-circulate globally and cause significant human disease. Dengue vaccine development is challenging because some virus-specific antibodies are protective, while others are implicated in enhanced viral replication and
Autor:
Longping V. Tse, Rita M. Meganck, Stephanie Dong, Lily E. Adams, Laura J. White, Michael L. Mallory, Ramesh Jadi, Aravinda M. de Silva, Ralph S. Baric
Publikováno v:
mBio. 13
Mature DENVs represent the dominant form in vivo and are the target for vaccine development. Here, we used multiple strategies, including protein engineering and natural and directed evolution to generate DENV1, -2, -3, and -4 variants that are highl
Autor:
Wan-ting He, Rami Musharrafieh, Ge Song, Katharina Dueker, Longping V. Tse, David R. Martinez, Alexandra Schäfer, Sean Callaghan, Peter Yong, Nathan Beutler, Jonathan L. Torres, Reid M. Volk, Panpan Zhou, Meng Yuan, Hejuni Liu, Fabio Anzanello, Tazio Capozzola, Mara Parren, Elijah Garcia, Stephen A. Rawlings, Davey M. Smith, Ian A. Wilson, Yana Safonova, Andrew B. Ward, Thomas F. Rogers, Ralph S. Baric, Lisa E. Gralinski, Dennis R. Burton, Raiees Andrabi
Publikováno v:
Nature immunology, vol 23, iss 6
Nat Immunol
bioRxiv
Nat Immunol
bioRxiv
SUMMARYThe emergence of current SARS-CoV-2 variants of concern (VOCs) and potential future spillovers of SARS-like coronaviruses into humans pose a major threat to human health and the global economy 1–7. Development of broadly effective coronaviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cb30cf9d2ef8c64fbdbe66913c4bd3
https://escholarship.org/uc/item/1c37m2gx
https://escholarship.org/uc/item/1c37m2gx