Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Longping V Tse"'
Autor:
Rita M Meganck, Deanna Zhu, Stephanie Dong, Lisa J Snoderly-Foster, Yago R Dalben, Devina Thiono, Laura J White, Arivianda M DeSilva, Ralph S Baric, Longping V Tse
Publikováno v:
eLife, Vol 12 (2023)
A hallmark of dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://doaj.org/article/052e2b8492e2439d954641c9e43adbfa
Autor:
Victoria J Madigan, Julianne A Yuziuk, Anna M Chiarella, Tyne O Tyson, Rita M Meganck, Zachary C Elmore, Longping V Tse, Nathaniel A Hathaway, Aravind Asokan
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007988 (2019)
Adeno-associated viruses (AAV) are Dependoparvoviruses that have shown promise as recombinant vectors for gene therapy. While infectious pathways of AAV are well studied, gaps remain in our understanding of host factors affecting vector genome expres
Externí odkaz:
https://doaj.org/article/fc7fbedd06ca440da188d4b61628143e
Autor:
Huatao Guo, Longping V Tse, Angela W Nieh, Elizabeth Czornyj, Steven Williams, Sabrina Oukil, Vincent B Liu, Jeff F Miller
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002414 (2011)
Diversity-generating retroelements (DGRs) are in vivo sequence diversification machines that are widely distributed in bacterial, phage, and plasmid genomes. They function to introduce vast amounts of targeted diversity into protein-encoding DNA sequ
Externí odkaz:
https://doaj.org/article/f06838c4f6d54e8d99df01a365f85838
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Emerging coronaviruses (CoV) are constant global public health threats to society. Multiple ongoing clinical trials for vaccines and antivirals against CoVs showcase the availability of medical interventions to both prevent and treat the future emerg
Externí odkaz:
https://doaj.org/article/fb10e439aeef47708bec3eaead6dddc7
Autor:
Rita M. Meganck, Deanna Zhu, Stephanie Dong, Lisa J. Snoderly-Foster, Yago R. Dalben, Devina Thiono, Laura J. White, Aravinda M. DeSilva, Ralph S. Baric, Longping V. Tse
Publikováno v:
bioRxiv
A hallmark of Dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ed5d83705e9b49ba9f8de7f86938f1
https://europepmc.org/articles/PMC10081285/
https://europepmc.org/articles/PMC10081285/
Autor:
Ellen Young, Boyd Yount, Petraleigh Pantoja, Sandra Henein, Rita M. Meganck, Jennifer McBride, Jennifer E. Munt, Thomas J. Baric, Deanna Zhu, Trevor Scobey, Stephanie Dong, Longping V. Tse, Melween I. Martinez, Armando G. Burgos, Rachel L. Graham, Laura White, Aravinda DeSilva, Carlos A. Sariol, Ralph S. Baric
Publikováno v:
Nature Communications. 14
The four dengue virus serotypes co-circulate globally and cause significant human disease. Dengue vaccine development is challenging because some virus-specific antibodies are protective, while others are implicated in enhanced viral replication and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::919cc5c043cb21730d1cfff55e3f2863
https://doi.org/10.1038/s41467-023-36702-x
https://doi.org/10.1038/s41467-023-36702-x
Autor:
Longping V. Tse, Rita M. Meganck, Stephanie Dong, Lily E. Adams, Laura J. White, Michael L. Mallory, Ramesh Jadi, Aravinda M. de Silva, Ralph S. Baric
Publikováno v:
mBio. 13
Mature DENVs represent the dominant form in vivo and are the target for vaccine development. Here, we used multiple strategies, including protein engineering and natural and directed evolution to generate DENV1, -2, -3, and -4 variants that are highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a4532c9ae65fcd891fd222da15c327
https://doi.org/10.1128/mbio.00386-22
https://doi.org/10.1128/mbio.00386-22
Autor:
Wan-ting He, Rami Musharrafieh, Ge Song, Katharina Dueker, Longping V. Tse, David R. Martinez, Alexandra Schäfer, Sean Callaghan, Peter Yong, Nathan Beutler, Jonathan L. Torres, Reid M. Volk, Panpan Zhou, Meng Yuan, Hejuni Liu, Fabio Anzanello, Tazio Capozzola, Mara Parren, Elijah Garcia, Stephen A. Rawlings, Davey M. Smith, Ian A. Wilson, Yana Safonova, Andrew B. Ward, Thomas F. Rogers, Ralph S. Baric, Lisa E. Gralinski, Dennis R. Burton, Raiees Andrabi
Publikováno v:
Nature immunology, vol 23, iss 6
Nat Immunol
bioRxiv
Nat Immunol
bioRxiv
SUMMARYThe emergence of current SARS-CoV-2 variants of concern (VOCs) and potential future spillovers of SARS-like coronaviruses into humans pose a major threat to human health and the global economy 1–7. Development of broadly effective coronaviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cb30cf9d2ef8c64fbdbe66913c4bd3
https://escholarship.org/uc/item/1c37m2gx
https://escholarship.org/uc/item/1c37m2gx
Autor:
Fabio T. M. Costa, Tatyana Almeida Tavella, Matthew B. Frieman, Nathaniel J. Moorman, Nicole J Johnson, Longping V. Tse, Kenneth H. Pearce, Carolina Horta Andrade, James A Levi, Ana C. Puhl, Ralph S. Baric, Carolina Q. Sacramento, Ethan J. Fritch, Natalia Fintelman-Rodrigues, Thomas J. Lane, Stuart Weston, Lakshmanane Premkumar, Peter B. Madrid, Brett L. Hurst, Sean Ekins, Thiago Moreno L. Souza, Boyd Yount, Samantha C Kisthardt, James Logue, Frank Scholle
Publikováno v:
ACS Omega, Vol 6, Iss 11, Pp 7454-7468 (2021)
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Omega
bioRxiv
article-version (status) pre
article-version (number) 1
ACS Omega
SARS-CoV-2 is a newly identified virus that has resulted in over 1.3 M deaths globally and over 59 M cases globally to date. Small molecule inhibitors that reverse disease severity have proven difficult to discover. One of the key approaches that has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe677ce706f0043425330437c4ba00d
https://doi.org/10.1021/acsomega.0c05996
https://doi.org/10.1021/acsomega.0c05996
Autor:
Longping V. Tse, Rita M. Meganck, Kenza C. Araba, Boyd L. Yount, Kendall M. Shaffer, Yixuan J. Hou, Jennifer E. Munt, Lily E. Adams, Jason A. Wykoff, Jeremy M. Morowitz, Stephanie Dong, Scott T. Magness, William F. Marzluff, Liara M. Gonzalez, Camille Ehre, Ralph S. Baric
Zoonotic transmission of coronaviruses poses an ongoing threat to human populations. Endemic outbreaks of swine acute diarrhea syndrome coronavirus (SADS-CoV) have caused severe economic losses in the pig industry and have the potential to cause huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e5a38ed6dfae5f3769e765ba9d167d