Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Longlong Jin"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 80:129115
A series of novel 2-fluoro ketolide antibiotics with 11,12-quinoylalkyl side chains derived from telithromycin and cethromycin were designed and synthesized. The corresponding targets 2a-o were tested for their in vitro activities against a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1293451a78d33fef08a9644f3ed4e949
https://doi.org/10.1016/j.bmcl.2022.129115
https://doi.org/10.1016/j.bmcl.2022.129115
Publikováno v:
Tetrahedron Letters. 59:1208-1211
A facile procedure was developed to synthesize novel N-glycoside josamycin derivatives by coupling 4′-amino-desmycarosyl josamycin derivatives with l- mycarose. A novel N-glycoside josamycin derivative 10a and a key intermediate 9a were designed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3559fb3d4a691e4816227f4d342bedd0
https://doi.org/10.1016/j.tetlet.2018.02.027
https://doi.org/10.1016/j.tetlet.2018.02.027
Publikováno v:
Journal of Asian Natural Products Research. 19:358-387
Some novel josamycin derivatives bearing an arylalkyl-type side chain were designed and synthesized. By HWE or Wittig reaction, 16-aldehyde group of josamycin analogs were converted into unsaturated carbonyl compounds. They were evaluated for their i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b8d6a3cfcb46f914439b80e0e49118
https://doi.org/10.1080/10286020.2016.1194834
https://doi.org/10.1080/10286020.2016.1194834
Publikováno v:
Tetrahedron. 72:4091-4102
A series of novel OSW-1 analogues were synthesized by coupling disaccharides (2-O-4-methoxylbenzoyl-β- d -xylopyranosyl-(1→3)-2-O-acetyl-α- l -arabinopyranosyl) or (2-O-4-(E)-cinnamoyl-β- d -xylopyranosyl-(1→3)-2-O-acetyl-α- l -arabinopyranos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3074d9b17b4e4cf7daff4703a17f3f2d
https://doi.org/10.1016/j.tet.2016.05.049
https://doi.org/10.1016/j.tet.2016.05.049
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(14)
A series of quinoylalkyl side chains was designed and synthesized, followed by introduction into ketolides by coupling with building block 6 or 32. The corresponding targets 7a-n, 33b, and 33e were tested for their in vitro activities against a serie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e62b9b393a76b9f69708618ad2a61ad
https://pubmed.ncbi.nlm.nih.gov/29937059
https://pubmed.ncbi.nlm.nih.gov/29937059
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:480-484
A series of novel 9-O-acetyl-4′-substituted 16-membered macrolides derived from josamycin has been designed and synthesized by cleavage of the mycarose of josamycin and subsequent modification of the 4′-hydroxyl group. These derivatives were eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582ae637835440ead6aa32166130a03f
https://doi.org/10.1016/j.bmcl.2013.12.029
https://doi.org/10.1016/j.bmcl.2013.12.029
Autor:
Suping Cai, Liyu Huang, Jia Zou, Longlong Jing, Buzhong Zhai, Gongjun Ji, Karen M von Deneen, Junchan Ren, Aifeng Ren, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115573 (2015)
We used resting-state functional magnetic resonance imaging (fMRI) to investigate changes in the thalamus functional connectivity in early and late stages of amnestic mild cognitive impairment. Data of 25 late stages of amnestic mild cognitive impair
Externí odkaz:
https://doaj.org/article/907ea3cc3f6a4b38bc957897a585c02e