Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Longlong Gong"'
Autor:
Bo Cheng, Caichen Li, Jianfu Li, Longlong Gong, Peng Liang, Ying Chen, Shuting Zhan, Shan Xiong, Ran Zhong, Hengrui Liang, Yi Feng, Runchen Wang, Haixuan Wang, Hongbo Zheng, Jun Liu, Chengzhi Zhou, Wenlong Shao, Yuan Qiu, Jiancong Sun, Zhanhong Xie, Zhu Liang, Chenglin Yang, Xiuyu Cai, Chunxia Su, Wei Wang, Jianxing He, Wenhua Liang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Immune checkpoint inhibitors targeting the programmed cell death-1 (PD-1) protein significantly improve survival in patients with advanced non-small-cell lung cancer (NSCLC), but its impact on early-stage ground-glass opacity (GGO) lesions r
Externí odkaz:
https://doaj.org/article/4d3035096197434f92f7d17580465bb5
Autor:
Wenguang Pang, Longlong Gong, Wangpan Shi, Hongbo Zheng, Min Ye, Jiarong Chen, Ronggang Li, Xin Zhang, Dong Ren, Zheng Wang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Next generation sequencing (NGS) is typically used to reveal tumor gene variation feature for targeted therapy of various types of human cancers, including non-small cell lung cancer (NSCLC). Here, we report the role and potential applicable
Externí odkaz:
https://doaj.org/article/540032ce309749eab0772bfd6fc43da7
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Small cell carcinoma of the esophagus (SCCE) is a rare and highly malignant type of esophageal cancer with no standard treatment, facing challenges of resistance to conventional therapies. This study presents the cases of one extensive-stage and two
Externí odkaz:
https://doaj.org/article/8df837b925fd4c01b3aa8bb775156311
Autor:
Tianshu Hao, Jianglong Yu, Zhida Wu, Jie Jiang, Longlong Gong, Bingjun Wang, Hanze Guo, Huabin Zhao, Bin Lu, Simone Engelender, He He, Zhiyin Song
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Mitochondria are the key organelles for sensing oxygen, which is consumed by oxidative phosphorylation to generate ATP. Lysosomes contain hydrolytic enzymes that degrade misfolded proteins and damaged organelles to maintain cellular homeosta
Externí odkaz:
https://doaj.org/article/21df65c007b74e62808b5795885d6a13
Autor:
Yongjun Zhu, Weixin Wu, Liangliang Qiao, Jingfen Ji, Lunxi Duan, Longlong Gong, Dandan Ren, Feifei Li, Lihui Wei, Ke Pan
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Next-generation sequencing (NGS) is maturely applied for gene fusion detection. Although tumor fusion burden (TFB) has been identified as an immune marker for cancer, the relationship between these fusions and the immunogenicity a
Externí odkaz:
https://doaj.org/article/536dee1b96ca4be39b877788aeed64b6
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 852-861 (2023)
Abstract Background Recent studies suggest that tumor fusion burden (TFB) is a hallmark of immune infiltration in prostate cancer, the correlation of TFB with immune microenvironment, and genomic patterns in head and neck squamous cell carcinomas (HN
Externí odkaz:
https://doaj.org/article/03083f7e294d4197ab449f2fe3c6f5f2
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundRearrangements of the anaplastic lymphoma kinase (ALK) gene comprise a small subset of non-small cell lung cancer (NSCLC). Patients with NSCLC harboring ALK fusion proteins are sensitive to ALK tyrosine kinase inhibitors (TKIs). Various fus
Externí odkaz:
https://doaj.org/article/e8bc787eadb742488a1ceec980b5c1fa
Autor:
Liuning Li, Guojie Lu, Yang Liu, Longlong Gong, Xue Zheng, Hongbo Zheng, Weiguang Gu, Lin Yang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundMany clinical studies have shown that patients with non-small cell lung carcinoma (NSCLC) can benefit from immune checkpoint inhibitor (ICI) therapy; however, PD-L1 and tumor mutation burden (TMB), which are recommended by the NCCN guidelin
Externí odkaz:
https://doaj.org/article/7e55c005a2d94fabbe50ae7e3db9c0e6
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-13 (2019)
Abstract In many solid tumor types, tumor-associated macrophages (TAMs) are important components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly associated with poor survival in solid tumor patients. In this review, we de
Externí odkaz:
https://doaj.org/article/65f4734c9b214d01a4c92fd37177ee04
Publikováno v:
Polymers, Vol 10, Iss 4, p 364 (2018)
Piezoelectric poly(vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)) nanofibers fabricated by electrospinning have drawn increasing levels of attention in the fields of flexible sensors and nanogenerators. However, the directional dependence of pi
Externí odkaz:
https://doaj.org/article/c98ef20979ac4629bc96a93896d72c67