Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Longlong, Jin"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 80:129115
A series of novel 2-fluoro ketolide antibiotics with 11,12-quinoylalkyl side chains derived from telithromycin and cethromycin were designed and synthesized. The corresponding targets 2a-o were tested for their in vitro activities against a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1293451a78d33fef08a9644f3ed4e949
https://doi.org/10.1016/j.bmcl.2022.129115
https://doi.org/10.1016/j.bmcl.2022.129115
Publikováno v:
Tetrahedron Letters. 59:1208-1211
A facile procedure was developed to synthesize novel N-glycoside josamycin derivatives by coupling 4′-amino-desmycarosyl josamycin derivatives with l- mycarose. A novel N-glycoside josamycin derivative 10a and a key intermediate 9a were designed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3559fb3d4a691e4816227f4d342bedd0
https://doi.org/10.1016/j.tetlet.2018.02.027
https://doi.org/10.1016/j.tetlet.2018.02.027
Publikováno v:
Journal of Asian Natural Products Research. 19:358-387
Some novel josamycin derivatives bearing an arylalkyl-type side chain were designed and synthesized. By HWE or Wittig reaction, 16-aldehyde group of josamycin analogs were converted into unsaturated carbonyl compounds. They were evaluated for their i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b8d6a3cfcb46f914439b80e0e49118
https://doi.org/10.1080/10286020.2016.1194834
https://doi.org/10.1080/10286020.2016.1194834
Publikováno v:
Tetrahedron. 72:4091-4102
A series of novel OSW-1 analogues were synthesized by coupling disaccharides (2-O-4-methoxylbenzoyl-β- d -xylopyranosyl-(1→3)-2-O-acetyl-α- l -arabinopyranosyl) or (2-O-4-(E)-cinnamoyl-β- d -xylopyranosyl-(1→3)-2-O-acetyl-α- l -arabinopyranos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3074d9b17b4e4cf7daff4703a17f3f2d
https://doi.org/10.1016/j.tet.2016.05.049
https://doi.org/10.1016/j.tet.2016.05.049
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(14)
A series of quinoylalkyl side chains was designed and synthesized, followed by introduction into ketolides by coupling with building block 6 or 32. The corresponding targets 7a-n, 33b, and 33e were tested for their in vitro activities against a serie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e62b9b393a76b9f69708618ad2a61ad
https://pubmed.ncbi.nlm.nih.gov/29937059
https://pubmed.ncbi.nlm.nih.gov/29937059
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:480-484
A series of novel 9-O-acetyl-4′-substituted 16-membered macrolides derived from josamycin has been designed and synthesized by cleavage of the mycarose of josamycin and subsequent modification of the 4′-hydroxyl group. These derivatives were eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582ae637835440ead6aa32166130a03f
https://doi.org/10.1016/j.bmcl.2013.12.029
https://doi.org/10.1016/j.bmcl.2013.12.029