Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Longjian Niu"'
Autor:
Jia-Yong Zhong, Longjian Niu, Zhuo-Bin Lin, Xin Bai, Ying Chen, Feng Luo, Chunhui Hou, Chuan-Le Xiao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Here the authors establish a high throughput Pore-C (HiPore-C) method increasing the sequencing output of multi-way chromatin contacts and reveal single-allele topology diversity and cell type-specificity of 3D genome folding.
Externí odkaz:
https://doaj.org/article/fbc2c3b1c4364542a408df7a4501c1b7
Autor:
Zhaoying Shi, Jinsheng Xu, Longjian Niu, Wei Shen, Shuting Yan, Yongjun Tan, Xuebo Quan, Edwin Cheung, Kai Huang, Yonglong Chen, Li Li, Chunhui Hou
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112151- (2023)
Summary: Transposable elements (TEs) are abundant in metazoan genomes and have multifaceted effects on host fitness. However, the mechanisms underlying the functions of TEs are still not fully understood. Here, we combine Hi-C, ATAC-seq, and ChIP-seq
Externí odkaz:
https://doaj.org/article/c5ea80c57a604a68966ea98014a386d6
Autor:
Jialei Sun, Na He, Longjian Niu, Yingzhang Huang, Wei Shen, Yuedong Zhang, Li Li, Chunhui Hou
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 17, Iss 2, Pp 140-153 (2019)
Enhancers activate transcription in a distance-, orientation-, and position-independent manner, which makes them difficult to be identified. Self-transcribing active regulatory region sequencing (STARR-seq) measures the enhancer activity of millions
Externí odkaz:
https://doaj.org/article/926118e613f44921b4a461dbcb2a5d77
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Sacha Inchi (Plukenetia volubilis L.), which belongs to the Euphorbiaceae, has been considered a new potential oil crop because of its high content of polyunsaturated fatty acids in its seed oil. The seed oil especially contains h
Externí odkaz:
https://doaj.org/article/91e81bda8a60422eb2578240b45e637b
Autor:
Longjian Niu, Yan-Bin Tao, Mao-Sheng Chen, Qiantang Fu, Chaoqiong Li, Yuling Dong, Xiulan Wang, Huiying He, Zeng-Fu Xu
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 6, Pp 12513-12530 (2015)
Real-time quantitative PCR (RT-qPCR) is a reliable and widely used method for gene expression analysis. The accuracy of the determination of a target gene expression level by RT-qPCR demands the use of appropriate reference genes to normalize the mRN
Externí odkaz:
https://doaj.org/article/16c744e1175b41c98dc1e85f4a753861
Autor:
Jing Wan, Yingzhang Huang, Jiashuo Li, Chunhui Hou, Yonglong Chen, Na He, Jialei Sun, Edwin Cheung, Piaopiao Zheng, Wenjing Wang, Zhaoying Shi, Yongjun Tan, Yuedong Zhang, Li Li, Chao Fang, Wei Shen, Longjian Niu
Publikováno v:
Nature Genetics
Animal interphase chromosomes are organized into topologically associating domains (TADs). How TADs are formed is not fully understood. Here, we combined high-throughput chromosome conformation capture and gene silencing to obtain insights into TAD d
Autor:
Chuan-Le Xiao, Jiayong Zhong, Longjian Niu, Zhuobin Lin, Xin Bai, Ying Chen, Feng Luo, Chunhui Hou
Canonical three-dimensional (3D) genome structures represent the ensemble average of pairwise chromatin interactions but not the single-allele topologies in populations of cells. Recently developed Pore-C can capture multiway chromatin contacts that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::185fa60266cf5669cb52fea2b1ac9416
https://doi.org/10.21203/rs.3.rs-1761017/v1
https://doi.org/10.21203/rs.3.rs-1761017/v1
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2484
High-throughput chromosome conformation capture (Hi-C) enables the global quantification of chromatin interaction frequency in eukaryotic nuclei. This method is based on in situ Hi-C, in which chromatin is cross-linked with formaldehyde, then digeste
Publikováno v:
Plant Gametogenesis ISBN: 9781071622520
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5b6c61dd92004a7db39faa61accf189
https://doi.org/10.1007/978-1-0716-2253-7_5
https://doi.org/10.1007/978-1-0716-2253-7_5
STARR-seq assesses millions of fragments in parallel measuring enhancer activity quantitatively. Here we show that STARR-seq is critically flawed with a systematic error in the cells of Arabidopsis thaliana (A. thaliana). Large amount of self-transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2146059960a1abb3e7cf14acb7c9235
https://doi.org/10.1101/2020.10.20.346908
https://doi.org/10.1101/2020.10.20.346908