Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Longhuo Wu"'
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Cholesterol (CHO) is an essential component of the body. However, high CHO levels in the body can damage bone mass and promote osteoporosis. CHO accumulation can cause osteoblast apoptosis, which has a negative effect on bone form
Externí odkaz:
https://doaj.org/article/556b5d2df53444e9b662809256fe3a4c
Autor:
Zeyu Wang, Weimei Shi, Longhuo Wu, Yaosheng Xiao, Miaofei Wang, Sainan Zhang, Zhixi Chen, Guoqiang Yin, Xunlu Xie, Shengrong Bi, Shiwei Liu, Weihao Kong, Jianguo Zhou
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116501- (2024)
Osteoarthritis (OA) is a chronic joint disease, characterized by degenerative destruction of articular cartilage. Chondrocytes, the unique cell type in cartilage, mediate the metabolism of extracellular matrix (ECM), which is mainly constituted by ag
Externí odkaz:
https://doaj.org/article/aea2b1449819477887cedae4c6910c61
Autor:
Qun Ren, Zhaowen Liu, Longhuo Wu, Guoqiang Yin, Xunlu Xie, Weihao Kong, Jianguo Zhou, Shiwei Liu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115938- (2023)
Inflammation, a mechanism of the human body, has been implicated in many diseases. Inflammatory responses include the release of inflammatory mediators by activating various signaling pathways. CCAAT/enhancer binding protein β (C/EBPβ), a transcrip
Externí odkaz:
https://doaj.org/article/7c351d55444e4cc7968306edb6f75552
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/79314f77cf834738a5b4b881ef16c7b9
Autor:
Jishang Huang, Yongjun Ye, Yaosheng Xiao, Qun Ren, Qingluo Zhou, Mingliang Zhong, Linhui Jiao, Longhuo Wu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113829- (2022)
Long-term exposure to glucocorticoid (GC) contributes to the development of osteoporosis (OP), which is correlated with the risk of fracture. Pathologically, GC-induced bone loss is associated with osteoblast apoptosis. Geniposide (GEN), a natural oc
Externí odkaz:
https://doaj.org/article/56ac9ecfd76b4a1489be824183306b6b
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113296- (2022)
Acteoside (AC), a phenylpropanoid glycoside isolated from many dicotyledonous plants, has been demonstrated various pharmacological activities, including anti-oxidation, anti-inflammation, anti-cancer, neuroprotection, cardiovascular protection, anti
Externí odkaz:
https://doaj.org/article/958a5e4da53b48a9805a9593b2e3048f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f819696f930248e9b0a89638d387db6f
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Kaempferol has been reported to exhibit beneficial effect on the osteogenic differentiation in mesenchymal stem cells (MSC) and osteoblasts. In our previous study, dexamethasone (DEX) demonstrated inhibitory effect on MC3T3-E1 cells differentiation.
Externí odkaz:
https://doaj.org/article/e69e730666b74aa58ed47b3f0126bca7
Autor:
Yizhou Zheng, Yaosheng Xiao, Di Zhang, Shanshan Zhang, Jing Ouyang, Linfu Li, Weimei Shi, Rui Zhang, Hai Liu, Qi Jin, Zhixi Chen, Daohua Xu, Longhuo Wu
Publikováno v:
Cells, Vol 11, Iss 23, p 3838 (2022)
The authors wish to make the following changes to their paper [...]
Externí odkaz:
https://doaj.org/article/62b9121eb09f48548d42d2f11b827396
Autor:
Jing Ouyang, Yaosheng Xiao, Qun Ren, Jishang Huang, Qingluo Zhou, Shanshan Zhang, Linfu Li, Weimei Shi, Zhixi Chen, Longhuo Wu
Publikováno v:
Cells, Vol 11, Iss 18, p 2882 (2022)
7-Ketocholesterol (7KC) is one of the oxysterols produced by the auto-oxidation of cholesterol during the dysregulation of cholesterol metabolism which has been implicated in the pathological development of osteoporosis (OP). Oxiapoptophagy involving
Externí odkaz:
https://doaj.org/article/bf60c1fddcb746bf9aba06a9c30c3f55